Human nicotinamide N-methyltransferase pharmacogenetics: Gene sequence analysis and promoter characterization

Pharmacogenetics

Volumn 9, Issue 3, 1999, Pages 307-316

  Yan, Lan ^a   Otterness, Diane M ^a   Weinshilboum, Richard M ^a  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

Author keywords

Genetic polymorphisms; Methylation; Methyltransferase; Nicotinamide N methyltransferase; Pharmacogenetics

Indexed keywords

NICOTINAMIDE METHYLTRANSFERASE;

ARTICLE; DNA FLANKING REGION; DNA METHYLATION; DNA SEQUENCE; ENZYME ACTIVITY; EXON; GENE DELETION; GENE INSERTION; GENE SEQUENCE; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; INTRON; LIVER; LIVER BIOPSY; NORTHERN BLOTTING; PHARMACOGENETICS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS; WESTERN BLOTTING;

EID: 0032789634     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199906000-00005     Document Type: Article

References (33)

1. Aksoy S, Szumlanski CL, Weinshilboum RM. Human liver nicotinamide N-methyltransferase: cDNA cloning, expression and biochemical characterization. J Biol Chem 1994; 265:14835-14840.
2. Aksoy S, Brandriff BF, Ward V, Little PFR, Weinshilboum RM. Human nicotinamide N-methyltransferase gene: molecular cloning, structural characterization, and chromosomal localization. Genomics 1995; 29:555-561.
3. Alston TA, Abeles RH. Substrate specificity of nicotinamide methyltransferase isolated from porcine liver. Arch Biochem Biophys 1988; 260:601-608.
4. Ansher SS, Jakoby WB. Amine N-methyltransferases from rabbit liver. J Biol Chem 1986; 261:3996-4001.
5. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72:248-254.
6. Bucher P. Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences. J Mol Biol 1990; 212:563-578.
7. Chadwick RB, Conrad MP, McGinnis MD, Johnston-Dow L, Spurgeon SL, Kronick MN. Heterozygote and mutation detection by direct automated fluorescent DNA sequencing using a mutant Taq DNA polymerase. Biotechniques 1996; 20:676-683.
8. Cuomo R, Dattilo M, Pumpo R, Capuano G, Boselli L, Budillon G. Nicotinamide methylation in patients with cirrhosis. J Hepatol 1994; 20:138-142.
9. David CL, Szumlanski CL, DeVry CG, Park-Hah JO, Clarke S, Weinshilboum RM, Aswad DW. Human erythrocyte protein L-isoaspartyl methyltransferase: heritability of basal activity and genetic polymorphism for thermal stability. Arch Biochem Biophys 1997; 346:277-286.
10. Devereux J, Haeberli P, Smithies O. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res 1984; 12:387-395.
11. 14C]pyridine. Xenobiotica 1980; 10:151-157.
12. Editorial. SNP attack on complex traits. Nature Genet 1998; 20:217-218.
13. Graham FL, van der Eb AJ. A new technique for the assay of infectivity of human adenovirus. J Virol 1973; 52:456-467.
14. Green S, Buttrum S, Molloy H, Steventon G, Struman S, Waring R, et al. N-Methylation of pyridines in Parkinson's disease. Lancet 1991; 338:120-121.
15. Haley TJ. Review of the toxicology of paraquat (1, 1'-dimethyl-4, 4'-bipyridinium chloride). Clin Toxicol 1979; 14:1-46.
16. Lachman HM, Papolos DF, Saito T, Yu Y-M, Szumlanski CL, Weinshilboum RM. Human catechol O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 1996; 6:243-250.
17. Langston JW. MPTP and Parkinson's disease. Trends Neurosci 1985; 8:79-83.
18. Lundberg KS, Shoemaker DA, Adams MWW, Short JM, Sorge JA, Mathur EJ. High-fidelity amplification using a thermostable DNA polymerase isolated from Pyrococcus furiosus. Gene 1991; 108:1-6.
19. Lyon ES. Jakoby WB. Arylamine N-methyltransferase. J Biol Chem 1982; 257:7531-7535.
20. Nickerson DA, Taylor SL, Weiss KM, Clark AG, Hutchinson RG, Stengard J, et al. DNA sequence diversity in a 9.7 kb region of the human lipoprotein lipase gene. Nature Genet 1998; 19:233-240.
21. Otterness DM, Her C, Aksoy S, Kimura S, Wieben ED, Weinshilboum RM. Human dehydroepiandrosterone sulfotransferase gene: molecular cloning and structural characterization. DNA Cell Biol 1995; 14:331-341.
22. Parker BA, Stark GR. Regulation of simian virus 40 transcription: sensitive analysis of the RNA species present early in infections by virus or viral DNA. J Virol 1979; 31:360-369.
23. Preuss CV, Wood TC, Szumlanski CL, Raftogianis RB, Otterness DM, Girard B, et al. Human histamine N-methyltransferase pharmacogenetics: common genetic polymorphisms that alter activity. Mol Pharmacol 1998; 53:708-717.
24. Price RA, Keith RA, Spielman RS, Weinshilboum RM. Major gene polymorphism for human erythrocyte (RBC) thiol methyltransferase (TMT). Genet Epidemiol 1989; 6:651-662.
25. Price RA, Scott MC, Weinshilboum RM. Genetic segregation analysis of red blood cell (RBC) histamine N-methyltransferase (HNMT) activity. Genet Epidemiol 1993; 10:123-131.
26. Rini J, Szumlanski C, Guerciolini R, Weinshilboum RM. Human liver nicotinamide N-methyltransferase: ion-pairing radiochemical assay, biochemical properties and individual variation. Clin Chim Acta 1989; 186:359-374.
27. Singer TP, Castagnoi Jr N, Ramsay RR, Trevor AJ. Biochemical events in the development of Parkinsonism induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine. J Neurochem 1987; 49:1-8.
28. Szumlanski C, Otterness D, Her C, Lee D, Brandriff B, Kelsell D, et al. Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterization of a common polymorphism. DNA Cell Biol 1996; 15:17-30.
29. Weinshilboum RM, Raymond FA. Inheritance of low erythrocyte catechol-O-methyltransferase activity in man. Am J Hum Genet 1977; 29:125-135.
30. Weinshilboum RM, Sladek SL. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet 1980; 32:651-662.
31. Weinshilboum RM, Otterness DM, Szumlanski CL. Methylation pharmacogenetics: catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase. Annu Rev Pharmacol Toxicol 1999; 39:19-52.
32. Yan L, Otterness DM, Craddock TL, Weinshilboum RM. Mouse liver nicotinamide N-methyltransferase: cDNA cloning, expression and nucleotide sequence polymorphisms. Biochem Pharmacol 1997; 54:1139-1149.
33. Yan L, Otterness DM, Kozak CA, Weinshilboum RM. Mouse nicotinamide N-methyltransferase gene: molecular cloning, structural characterization and chromosomal localization. DNA Cell Biol 1998; 17:659-667.