Selective amino acid substitutions of a subdominant Epstein-Barr virus LMP2-derived epitope increase HLA/peptide complex stability and immunogenicity: Implications for immunotherapy of Epstein-Barr virus-associated malignancies

European Journal of Immunology

Volumn 29, Issue 8, 1999, Pages 2579-2589

  Micheletti, Fabiola ^a   Guerrini, Remo ^a   Formentin, Annarita ^a   Canella, Alessandro ^a   Marastoni, Mauro ^a   Bazzaro, Martina ^a   Tomatis, Roberto ^a   Traniello, Serena ^a   Gavioli, Riccardo ^a,b  

^a UNIVERSITY OF FERRARA   (Italy)

^b Dipto di Biochim e Biol Molec   (Italy)

Author keywords

Cytotoxic T lymphocyte; Epitope; Epstein Barr virus; HLA class I

Indexed keywords

HLA A ANTIGEN; MEMBRANE PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CELLULAR IMMUNITY; CONTROLLED STUDY; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; IMMUNOGENICITY; IMMUNOTHERAPY; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGENS, VIRAL; CELL LINE; EPITOPES; EPSTEIN-BARR VIRUS INFECTIONS; HERPESVIRUS 4, HUMAN; HLA-A ANTIGENS; HUMANS; IMMUNOLOGIC MEMORY; IMMUNOTHERAPY; T-LYMPHOCYTES, CYTOTOXIC; VIRAL MATRIX PROTEINS;

EID: 0032788204     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199908)29:08<2579::AID-IMMU2579>3.0.CO;2-E     Document Type: Article

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