Establishment of anti-Epstein-Barr virus (EBV) cellular immunity by adoptive transfer of virus-specific cytotoxic T lymphocytes from an HLA-matched sibling to a patient with severe chronic active EBV infection

Clinical and Experimental Immunology

Volumn 103, Issue 2, 1996, Pages 192-198

  Kuzushima, K ^a   Yamamoto, M ^a   Kimura, H ^a   Ando, Y ^a   Kudo, T ^a   Tsuge, I ^a   Morishima, T ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adoptive transfer; Chronic active EBV infection; Cytotoxic T lymphocyte; Epstein Barr virus

Indexed keywords

HLA ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ADOPTIVE TRANSFER; ARTICLE; CASE REPORT; CELLULAR IMMUNITY; CYTOTOXIC T LYMPHOCYTE; HERPES VIRUS INFECTION; HUMAN; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; SIBLING; STREPTOCOCCUS PNEUMONIAE;

CHILD; CHRONIC DISEASE; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 4, HUMAN; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HUMANS; IMMUNITY, CELLULAR; IMMUNOTHERAPY, ADOPTIVE; LYMPHOCYTE TRANSFUSION; MALE; T-LYMPHOCYTES, CYTOTOXIC; TUMOR VIRUS INFECTIONS;

EID: 0030069315     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1996.d01-619.x     Document Type: Article

References (38)

1. Klein G. Viral latency and transformation: the strategy of Epstein-Barr virus. Cell 1989; 58:5-8.
2. Kleiff E, Liebowitz D. Epstein-Barr virus and its replication. In: Fields BN, ed. Virology. New York: Raven Press, 1990: 1889-920.
3. Weiss LM, Movahed LA, Warnke RA, Sklar J. Detection of Epstein-Barr viral genomes in Reed-Sternberg cells of Hodgkin's disease. N Engl J Med 1989; 320:502-6.
4. Epstein MA, Achong BG, Barr YM. Virus particles in cultured lymphoblasts from Burkitt's lymphoma. Lancet 1964; i:702-3.
5. Okano M, Mizuno F, Osato T. Wiskott-Aldrich syndrome and Epstein-Barr virus-induced lymphoproliferation. Lancet 1984; ii:933-4.
6. Saemundsen AK, Berkel AI, Henle W et al. Epstein-Barr virus carrying lymphoma in a patient with ataxiatelangiectasia. B Med J 1981; 282:425-7.
7. Purtilo DT, Cassel CK, Yang JPS, Harper P. X-linked recessive progressive combined variable immunodeficiency (Duncan's disease). Lancet 1975; i:935-40.
8. Shapiro RS, McClain K, Frizzeran G et al. Epstein-Barr virus associated B cell lymphoproliferative disorders following bone marrow transplantation. Blood 1988; 71:1234-43.
9. Zutter MM, Martin PJ, Sale GE et al. Epstein Barr virus lymphoproliferation after bone marrow transplantation. Blood 1988; 72:520-9.
10. Gratama JW, Zutter MM, Minaovits J et al. Expression of Epstein Barr virus-encoded growth-transformation-associated proteins in lymphoproliferations of bone marrow transplant recipients. Int J Cancer 1991; 47:188-92.
11. Schooley RT, Carey RW, Miller G et al. Chronic Epstein-Barr virus infection associated with fever and interstitial pneumonitis. Clinical and serolgic features and response to antiviral chemotherapy. Ann Intern Med 1986;104:636-43.
12. Okano M, Matsumoto S, Osato T et al. Severe chronic active Epstein-Barr virus infection syndrome. Clin Microbiol Rev 1991; 4:129-35.
13. Kikuta H, Taguchi K, Tomizawa K et al. Epstein-Barr virus genome-positive T lymphocytes in a boy with chronic active EBV infection associated with Kawasaki-like disease. Nature (London) 1988; 333:455-7.
14. Tobi M, Ravid Z, Feldman-Weiss V et al. Prolonged atypical illness associated with serological evidence of persistent Epstein-Barr virus infection. Lancet 1982; i:61-64.
15. Rickinson AB. Chronic, symptomatic Epstein-Barr virus infection. Immunol Today 1986; 7:13-14.
16. Ishihara S, Kawa-Ha, Okada S et al. Clinical and epidemiological characteristics of chronic active EB virus infection in Japan. J Jpn Pediatr Soc 1991; 90:80-90.
17. Okano M, Thiele GM, Davis JR et al. Adenovirus type-2 in a patient with lethal hemorrhagic colonie ulcers and chronic active Epstein-Barr virus infection. Ann Intern Med 1988; 108:693-9.
18. Jones JF, Shurin S, Abramowsky C et al. T-cell lymphomas containing Epstein-Barr viral DNA in patients with chronic Epstein Barr virus infections. N Engl J Med 1988; 318:733-41.
19. Kawa-Ha K, Franco E, Doi S et al. Successful treatment of chronic active Epstein Barr virus infection with recombinant interleukin-2. Lancet 1987; i:154.
20. Ishida Y, Yokota Y, Tauchi H et al. Ganciclovir for chronic active Epstein Barr virus infection. Lancet 1993; 341:560-1.
21. Moss DJ, Rickinson AB, Pope JH. Long term T-cell-mediated immunity to Epstein-Barr virus in man. I. Complete regression of virus-induced transformation in cultures of seropositive donor leukocytes. Int J Cancer 1987; 22:662-8.
22. Sugamura K, Hinuma Y. In vitro induction of cytotoxic T lymphocytes specific for Epstein-Barr virus transformed cells: kinetics of autologous restimulation. J Immunol 1980; 124:1045-9.
23. Kimura H, Tsuge I, Imai S et al. Intact antigen presentation for Epstein-Barr virus (EBV)-specific CTL by a lymphoblastoid cell line established from a patient with severe chronic active EBV infection. Med Microbiol Immunol, 1995; 184:63-68.
24. Kuis W, Roord JJ, Zeger BJM et al. Heterogeneity of immune defects in three children with a chronic active Epstein-Barr virus infection. J Clin Immunol 1985; 5:377-85.
25. Tosato G, Straus S, Henle W, Pike SE, Blaese RM. Characteristic T cell dysfunction in patients with chronic active Epstein-Barr virus infection (chronic infectious mononucleosis). J Immunol 1985; 134:3082-8.
26. Finlay J, Luft B, Yousem S et al. Chronic infectious mononucleosis syndrome, pancytopenia and polyclonal B-lymphoproliferation terminating in acute lymphoblastic leukemia. Am J Pediatr Hematol Oncol 1986; 8:18.
27. Wakiguchi H, Fujieda M, Matsumoto K et al. Defective killer cell activity in patients with chronic active Epstein-Barr virus infection. Acta Med Okayama 1988; 42:137-42.
28. Papadopoulos EB, Ladanyi M, Emanuel D et al. Infusions of donor leukocytes to treat Epstein-Barr virus-associated lymphoproliferative disorders after allogeneic bone marrow transplantation. N Engl J Med 1994; 330:1185-91.
29. Rooney CM, Smith CA, Ng CYC et al. Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation. Lancet 1995; 345:9-13.
30. Boyle TJ, Berend KR, DiMaio JM et al. Adoptive transfer of cytotoxic T lymphocytes for the treatment of transplant-associated lymphoma. Surgery 1993; 114:218-26.
31. Henke A, Mohr C, Sprenger II et al. Coxsackievirus B3-induced production of tumor necrosis factor-α, IL-1β, and IL-6 in human monocytes. J Immunol 1992; 148:2270-7.
32. Shibata M, Terashima M, Kimura H et al. Quantitation of cytomegalovirus DNA in lung tissue of bone marrow transplant recipients. Human Pathol 1992; 23:911-5.
33. Ando Y, Kimura H, Miwata H et al. Quantitative analysis of herpes simplex vius DNA in cerebrospinal fluid of children with herpes simplex encephalitis. J Med Virol 1993; 41:170-3.
34. Yamamoto M, Kimura H, Hironaka T et al. Detection and quantification of virus DNA in plasma of patients with Epstein-Barr virus-associated disease. J Clin Microbiol 1995; 33:1765-8.
35. Williams LL, Rooney CM, Conley ME et al. Correction of Duncan's syndrome by allogeneic bone marrow transplantation. Lancet 1993; 342:587-8.
36. Filipovith AH, Blazar BR, Ramsey NKC et al. Allogeneic bone marrow transplantation for X-linked lymphoproliferative syndrome. Transplantation 1986; 42:222-4.
37. Vooft PJ, Fibbe WE, Marijt WAF et al. Rejection of bone-marrow graft by recipient-derived cytotoxic T lymphocytes against minor histocompatibility antigens. Lancet 1990; 335:131-4.
38. Cournoyer D, Caskey CT. Gene therapy of the immune system. Annu Rev Immunol 1993; 11:297-329.