Puva (8-methoxy-psoralen plus ultraviolet A) induces the formation of 8- hydroxy-2'-deoxyguanosine and DNA fragmentation in calf thymus DNA and human epidermoid carcinoma cells

Free Radical Biology and Medicine

Volumn 27, Issue 1-2, 1999, Pages 127-133

  Liu, Zhisong ^a   Lu, Yuhun ^a   Lebwohl, Mark ^a   Wei, Huachen ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

8 MOP; 8 OHdG; Antioxidants; DNA fragmentation; Free radicals; PUVA; ROS; UVA

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ACETYLCYSTEINE; CATALASE; DNA FRAGMENT; GENISTEIN; MANNITOL; PSORALEN; REACTIVE OXYGEN METABOLITE; SODIUM AZIDE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL CULTURE; CHEMICAL REACTION; DNA DAMAGE; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PUVA; SKIN DISEASE; SPECTROFLUOROMETRY; SQUAMOUS CELL CARCINOMA; ULTRAVIOLET B RADIATION;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CATTLE; DEOXYGUANOSINE; DNA; DNA DAMAGE; DNA FRAGMENTATION; HUMANS; METHOXSALEN; REACTIVE OXYGEN SPECIES; THYMUS GLAND; TUMOR CELLS, CULTURED; ULTRAVIOLET RAYS;

ANIMALIA;

EID: 0032782636     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(99)00058-1     Document Type: Article

References (36)

1. Parrish J.A., Fitzpatrick T.B., Tanenbaum L., Pathak M.A. Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light. N. Engl. J. Med. 291:1974;1207-1211.
2. Pathak M.A., Kramer D.M. Photosensitization of skin in vivo by furocoumarins (psoralens). Biochem. Biophys. Acta. 195:1969;197-206.
3. Johnston B.H., Johnson M.A., Moore C.B., Hearst J.E. Psoralen-DNA photoreaction controlled production of mono- and diadducts with nanosecond ultraviolet laser pulses . Science. 197:1977;906-908.
4. Cadet J., Voituriez L., Nardin R., Viari A., Vigny P. A new class of psoralen photoadducts to DNA components isolation and characterization of 8-MOP adducts to the osidic moiety of 2'-deoxyadenosine . J. Photochem. Photobiol. 2:1988;321-329.
5. Stern R.S., Lange R. Non-melanoma skin cancer occurring in patients treated with PUVA five to ten years after first treatment. J. Invest. Dermatol. 91:1988;120-124.
6. Forman A.B., Roenigk H.H. Jr, Caro W.A., Magid M.L. Long-term follow-up of skin cancer in the PUVA-48 cooperative study. Arch. Dermatol. 125:1989;515-519.
7. Stern R.S., Nichols K.T., Vakeva L.H. Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA). N. Engl. J. Med. 336:1997;1041-1045.
8. Tessman J.W., Isaacs S.T., Hearst J.E. Photochemistry of the furan-side 8-methoxypsoralen-thymidine monoadduct inside the DNA helix. Conversion to diadduct and to pyrone-side monoadduct. Biochemistry. 24:1985;1669-1676.
9. Nataraj A.J., Black H.S., Ananthaswamy H.N. Signature p53 mutation at DNA cross-linking sites in 8-methoxypsoralen and ultraviolet A (PUVA)-induced murine skin cancers. Proc. Natl. Acad. Sci. USA. 93:1996;7961-7965.
10. Nataraj A.J., Wolf P., Cerroni L., Ananthaswamy H.N. p53 mutation in squamous cell carcinomas from psoriasis patients treated with psoralen +UVA (PUVA). J. Invest Dermatol. 109:1997;238-243.
11. Wang X.M., McNiff J.M., Klump V., Asgari M., Gasparro F.P. An unexpected spectrum of p53 mutations from squamous cell carcinomas in patients treated with PUVA. Photochem. Photobiol. 66:1997;294-299.
12. Foote C.S. Definition of type I and type II photosensitized oxidation. Photochem. Photobiol. 54:1990;659.
13. Lee P.C.C., Rodgers M.A. Laser flash photokinetic studies of rose bengal sensitized photodynamic interactions of nucleotides and DNA. Photochem. Photobiol. 45:1987;79-86.
14. Pathak M.A., Joshi P.C. Production of active oxygen species by psoralen and ultraviolet-radiation (320-400 nm). Biochim. Biophys. Acta. 798:1984;115-126.
15. Frenkel K. Carcinogen-mediated oxidant formation and oxidative DNA damage. Pharmacol. Ther. 53:1992;127-166.
16. Floyd R.A. The role of 8-hydroxydeoxyguanosine in carcinogenesis. Carcinogenesis. 11:1990;1447-1450.
17. Ames B.N., Gold L.S. Endogenous mutagens and the cause of aging and cancer. Mutat. Res. 250:1991;3-16.
18. Kasai H., Nishimura S., Kurokawa Y., Hayashi Y. Oral administration of the renal carcinogen, potassium bromate, specifically produces 8-hydroxydeoxyguanosine in rat target organ DNA. Carcinogenesis. 8:1987;1959-1961.
19. Wei H., Frenkel K. In vivo formation of oxidized DNA bases in tumor promoter-treated mouse skin. Cancer Res. 51:1991;4443-4449.
20. Wei H., Frenkel K. Relationship of oxidative events and DNA oxidation in SENCAR mice to in vivo promoting activity of phorbol ester-type tumor promoters. Carcinogenesi. 14:1993;1195-1201.
21. Ichinose T., Yajima Y., Nagashima M., Takenoshita S., Nagamachi Y., Sagai M. Lung carcinogenesis and formation of 8-hydroxy-deoxyguanosine in mice by diesel exhaust particles. Carcinogenesis. 18:1997;185-192.
22. Olinski R., Zastawny T., Budzbon J., Skokowski J., Zegarski W., Dizdaroglu M. DNA base modification in chromatin of human cancerous tissues. FEBS Lett. 309:1991;193-198.
23. Malins D.C., Haimanot R. Major alterations in the nucleotide structure of DNA in cancer of the female breast. Cancer Res. 51:1991;5430-5432.
24. Shibutani S., Takeshita M., Grollman A.P. Insertion of specific bases during DNA synthesis past the oxidation damaged DNA base 8-oxodG. Nature. 349:1991;431-434.
25. Cheng K.C., Cahill D.S., Kasai H., Nishimura S., Loeb L.A. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G→T and A→C substitutions. J. Biol. Chem. 267:1992;166-172.
26. Wei H., Cai Q., Rahn R. Inhibition of UV light- and Fenton reaction-induced oxidative DNA damage by the soybean isoflavone genistein. Carcinogenesis. 17:1996;73-77.
27. Wei H., Cai Q., Rahn R., Zhang X. Singlet oxygen involvement in ultraviolet (254 nm) radiation-induced formation of 8-hydroxy-deoxyguanosine in DNA. Free Radic. Biol. Med. 23:1997;148-154.
28. Zhang X., Rosenstein B.S., Wang Y., Lebwohl M., Mitchel D.M., Wei H. Induction of 8-oxo-7,8-dihydro-2'-deoxyguanosine by ultraviolet radiation in calf thymus DNA and HeLa cells. Photochem. Photobiol. 65:1997;119-124.
29. Zhang X., Rosenstein B., Wang Y., Lebwohl M., Wei H. Identification of possible reactive oxygen species involved in ultraviolet radiation-induced oxidative DNA damage. Free Radic. Biol. Med. 23:1997;980-985.
30. Wei H., Cai Q., Rahn R., Zhang X., Wang Y., Lebwohl M. DNA structural integrity and base composition affect ultraviolet light-induced oxidative DNA damage. Biochemistry. 37:1998;6485-6490.
31. Liu Z., Lu Y., Rosenstein B., Lebwohl M., Wei H. Benzo(a)pyrene enhances the formation of 8-hydroxyguanosine by ultraviolet radiation in calf thymus DNA and human epidermoid carcinoma cells. Biochemistry. 37:1998;10307-10312.
32. Jarvis D., Turner A.J., Povirk L.F., Traylor R.S., Grant S. Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C. Cancer Res. 54:1994;1707-1714.
33. Saed G., Fivenson D.P., Naidu Y., Nickoloff B.J. Mycosis fungoides exhibits a Th-1 type cell mediated cytokine profile whereas Sezary syndrome expresses a Th-2 type profile. J. Invest. Dermatol. 103:1994;29-33.
34. Enomoto D.N.H., Schellekens P.T.A., Yong S., ten Berge I.J.M., Mekkes J.R., Bos J.D. Extracorporeal photochemotherapy (photopheresis) induces apoptosis in Lymphocytes a possible mechanism of action of PUVA therapy . Photochem. Photobiol. 65:(1):1997;177-188.
35. Gasparro F.P., Liao B., Foley P.J., Wang X.M., McNiff J.M. Psoralen photochemotherapy, clinical efficacy, and photomutagenicity the role of molecular epidemiology in minimizing risks . Environ. Mol. Mutag. 31:1998;105-112.
36. Greenblatt M.S., Bennett W.P., Hollstein M., Harris C.C. Mutations in p53 tumor suppressor gene clues to cancer etiology and molecular pathogenesis . Cancer Res. 54:1994;4855-4878.