Computational modeling of the rate limiting step in low molecular weight protein tyrosine phosphatase

FEBS Letters

Volumn 456, Issue 2, 1999, Pages 301-305

  Kolmodin, Karin ^a   Åqvist, Johan ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Catalysis; Empirical valence bond method; Free energy perturbation; Molecular dynamic; Protein tyrosine phosphatase; Reaction free energy profile

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE;

ARTICLE; CATALYSIS; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; ENERGY TRANSFER; EQUILIBRIUM CONSTANT; HUMAN; HYDROLYSIS; PRIORITY JOURNAL;

ANIMALS; CATALYTIC DOMAIN; CATTLE; COMPUTER SIMULATION; HYDROLYSIS; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR WEIGHT; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN-TYROSINE-PHOSPHATASE; THERMODYNAMICS;

EID: 0032781425     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)00974-6     Document Type: Article

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