-
1
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
1. Slamon DJ, Godolphin W, Jones LA, Holt JA, Wong SG, Keith DE, Levin WJ, Stuart SG, Udove J, Ullrich A, Press MF: Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244:707-713, 1989
-
(1989)
Science
, vol.244
, pp. 707-713
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
Press, M.F.11
-
2
-
-
0026512772
-
Abberant expression of the c-erbB-2/neu protooncogene in ovarian cancer
-
2. Hung M-C, Zhang X, Yan D-H, Zhang H-Z, He G-P, Zhang T-Q, Shi D-R: Abberant expression of the c-erbB-2/neu protooncogene in ovarian cancer. Cancer Lett 61:95-103, 1992
-
(1992)
Cancer Lett
, vol.61
, pp. 95-103
-
-
Hung, M.-C.1
Zhang, X.2
Yan, D.-H.3
Zhang, H.-Z.4
He, G.-P.5
Zhang, T.-Q.6
Shi, D.-R.7
-
3
-
-
0027548648
-
Amplification and overexpression of the erbB-2 gene in human tumors: Its involvement in tumor development, significance as a prognostic factor, and potential as a target for cancer therapy
-
3. Hynes NE: Amplification and overexpression of the erbB-2 gene in human tumors: Its involvement in tumor development, significance as a prognostic factor, and potential as a target for cancer therapy. Cancer Biol 4:19-26, 1993
-
(1993)
Cancer Biol
, vol.4
, pp. 19-26
-
-
Hynes, N.E.1
-
4
-
-
0022102126
-
Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies
-
4. Drebin JA, Link VC, Stern DF, Weinberg RA, Greene MI: Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies. Cell 41:695-706, 1985
-
(1985)
Cell
, vol.41
, pp. 695-706
-
-
Drebin, J.A.1
Link, V.C.2
Stern, D.F.3
Weinberg, R.A.4
Greene, M.I.5
-
5
-
-
0028200221
-
Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells
-
5. Pietras RJ, Fendly BM, Chazin VR, Pegram MD, Howell SB, Slamon DJ: Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells. Oncogene 9:1829-1838, 1994
-
(1994)
Oncogene
, vol.9
, pp. 1829-1838
-
-
Pietras, R.J.1
Fendly, B.M.2
Chazin, V.R.3
Pegram, M.D.4
Howell, S.B.5
Slamon, D.J.6
-
6
-
-
0025752933
-
Selection of of monoclonal antibodies which induce internalization and phosphorylation of p185HER2 and growth inhibition of cells with HER2/neu gene amplification
-
6. Tagliabue E, Centis F, Campiglio M, Mastroianni A, Martignone S, Pellegrini R, Casalini P, Lanzi C, Menard S, Conalghi MI: Selection of of monoclonal antibodies which induce internalization and phosphorylation of p185HER2 and growth inhibition of cells with HER2/neu gene amplification. Int J Cancer 47:933-937, 1991
-
(1991)
Int J Cancer
, vol.47
, pp. 933-937
-
-
Tagliabue, E.1
Centis, F.2
Campiglio, M.3
Mastroianni, A.4
Martignone, S.5
Pellegrini, R.6
Casalini, P.7
Lanzi, C.8
Menard, S.9
Conalghi, M.I.10
-
7
-
-
0026685034
-
Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies
-
7. Kasprzyk PG, Song SU, Fiore PPD, King CR: Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies. Cancer Res 52:2771-2776, 1992
-
(1992)
Cancer Res
, vol.52
, pp. 2771-2776
-
-
Kasprzyk, P.G.1
Song, S.U.2
Fiore, P.P.D.3
King, C.R.4
-
8
-
-
0026755810
-
Recombinant anti-erbB2 immunotoxins containing pseudonoma exotoxin
-
8. Batra JK, Kasprzyk PG, Bird RE, Pastan I, King CR: Recombinant anti-erbB2 immunotoxins containing pseudonoma exotoxin. Proc Natl Acad Sci USA 89:5867-5871, 1992
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5867-5871
-
-
Batra, J.K.1
Kasprzyk, P.G.2
Bird, R.E.3
Pastan, I.4
King, C.R.5
-
9
-
-
0028238218
-
Reduction of erbB2 gene product in mamma carcinoma cell lines by erbB2 mRNA-specific and tyrosine kinase consensus phosphorothiate antisense oligonucleotides
-
9. Bertram J, Killian M, Brysch W, Schlingensiepen K-H, Kneba M: Reduction of erbB2 gene product in mamma carcinoma cell lines by erbB2 mRNA-specific and tyrosine kinase consensus phosphorothiate antisense oligonucleotides. Biochem Biophys Res Commun 200:661-667, 1994
-
(1994)
Biochem Biophys Res Commun
, vol.200
, pp. 661-667
-
-
Bertram, J.1
Killian, M.2
Brysch, W.3
Schlingensiepen, K.-H.4
Kneba, M.5
-
10
-
-
0028458317
-
Inhibition of p185c-erbB-2 proto-oncogene expression by antisense oligodeoxynucleotide down-regulates p185-associated tyrosine kinase activity and strongly inhibits mammary tumor-cell proliferation
-
10. Brysch W, Magal E, Louis J-C, Kunst M, Klinger I, Schlingensiepen R, Schlingensiepen K-H: Inhibition of p185c-erbB-2 proto-oncogene expression by antisense oligodeoxynucleotide down-regulates p185-associated tyrosine kinase activity and strongly inhibits mammary tumor-cell proliferation. Cancer Gene Ther 1:99-105, 1994
-
(1994)
Cancer Gene Ther
, vol.1
, pp. 99-105
-
-
Brysch, W.1
Magal, E.2
Louis, J.-C.3
Kunst, M.4
Klinger, I.5
Schlingensiepen, R.6
Schlingensiepen, K.-H.7
-
11
-
-
0028500163
-
Intracellular single-chain antibody directed against erbB2 down-regulates cell surface erb2 and exhibits a selective anti-proliferative effect in erbB2 overexpressing cancer cell lines
-
11. Deshane J, Loechel F, Conry RM, Siegal GP, King CR, Curiel DT: Intracellular single-chain antibody directed against erbB2 down-regulates cell surface erb2 and exhibits a selective anti-proliferative effect in erbB2 overexpressing cancer cell lines. Gene Ther 1:332-337, 1994
-
(1994)
Gene Ther
, vol.1
, pp. 332-337
-
-
Deshane, J.1
Loechel, F.2
Conry, R.M.3
Siegal, G.P.4
King, C.R.5
Curiel, D.T.6
-
12
-
-
0030101361
-
Intracellular antibody directed against erbB2 mediates tumor cell eradication by inducing apoptosis
-
12. Deshane J, Grim J, Loechel S, Siegal GP, Alvarez RD, King CR, Curiel DT: Intracellular antibody directed against erbB2 mediates tumor cell eradication by inducing apoptosis. Cancer Gene Ther 3:89-98, 1996
-
(1996)
Cancer Gene Ther
, vol.3
, pp. 89-98
-
-
Deshane, J.1
Grim, J.2
Loechel, S.3
Siegal, G.P.4
Alvarez, R.D.5
King, C.R.6
Curiel, D.T.7
-
13
-
-
0028823836
-
Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody
-
13. Deshane J, Cabrera G, Grim JE, Siegal GP, Pike J, Alvarez RD, Curiel DT: Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody. Gynecol Oncol 59:8-14, 1995
-
(1995)
Gynecol Oncol
, vol.59
, pp. 8-14
-
-
Deshane, J.1
Cabrera, G.2
Grim, J.E.3
Siegal, G.P.4
Pike, J.5
Alvarez, R.D.6
Curiel, D.T.7
-
14
-
-
0028839655
-
Targeted tumor killing via an intracellular antibody against erbB-2
-
14. Deshane J, Siegal GP, Alvarez RD, Wang M-H, Feng M, Cabrera G, Liu T, Kay M, Curiel DT: Targeted tumor killing via an intracellular antibody against erbB-2. J Clin Invest 96:2980-2989, 1995
-
(1995)
J Clin Invest
, vol.96
, pp. 2980-2989
-
-
Deshane, J.1
Siegal, G.P.2
Alvarez, R.D.3
Wang, M.-H.4
Feng, M.5
Cabrera, G.6
Liu, T.7
Kay, M.8
Curiel, D.T.9
-
15
-
-
85030290157
-
ErbB-2 knockout employing an intracellular single chain antibody (sFv) accomplishes specific toxicity in erbB-2 expressing lung cancer cells
-
in press
-
15. Grim J, Deshane J, Feng M, Lieber A, Kay M, Curiel DT: ErbB-2 knockout employing an intracellular single chain antibody (sFv) accomplishes specific toxicity in erbB-2 expressing lung cancer cells. Am J Respir Cell Mol Biol (in press)
-
Am J Respir Cell Mol Biol
-
-
Grim, J.1
Deshane, J.2
Feng, M.3
Lieber, A.4
Kay, M.5
Curiel, D.T.6
-
16
-
-
0028797820
-
In situ hybridization with digoxigenin-labeled RNA probes: Facts and artifacts
-
16. Panoskaltsis-Mortari A, Bucy RP: In situ hybridization with digoxigenin-labeled RNA probes: Facts and artifacts. Biotechniques 18:300-307, 19957
-
(1995)
Biotechniques
, vol.18
, pp. 300-307
-
-
Panoskaltsis-Mortari, A.1
Bucy, R.P.2
-
18
-
-
0029317897
-
Recombinant adenovirus-mediated gene transfer to genitourinary epithelium in vitro and in vivo
-
18. Bass C, Cabrera G, Elgavish A, Robert B, Siegal GP, Anderson SC, Maneval DC, Curiel DT: Recombinant adenovirus-mediated gene transfer to genitourinary epithelium in vitro and in vivo. Cancer Gene Ther 2:97-104, 1995
-
(1995)
Cancer Gene Ther
, vol.2
, pp. 97-104
-
-
Bass, C.1
Cabrera, G.2
Elgavish, A.3
Robert, B.4
Siegal, G.P.5
Anderson, S.C.6
Maneval, D.C.7
Curiel, D.T.8
-
19
-
-
85030281538
-
Adenoviral-mediated delivery of herpes simplex virus thymidine kinase results in tumor reduction and prolonged survival in a SCID mouse model of human ovarian carcinoma
-
in press
-
19. Rosenfeld ME, Wang M-H, Siegal GP, Alvarez RD, Mikheeva G, Krasnykh V, Curiel DT: Adenoviral-mediated delivery of herpes simplex virus thymidine kinase results in tumor reduction and prolonged survival in a SCID mouse model of human ovarian carcinoma. J Mol Med (in press)
-
J Mol Med
-
-
Rosenfeld, M.E.1
Wang, M.-H.2
Siegal, G.P.3
Alvarez, R.D.4
Mikheeva, G.5
Krasnykh, V.6
Curiel, D.T.7
-
20
-
-
0028340984
-
Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma
-
20. Smythe WR, Kaiser LR, Hwang HC, Amin KM, Pilewski JM, Eck SJ, Wilson JM, Abelda SM: Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma. Ann Thorac Surg 57:1395-1401, 1994
-
(1994)
Ann Thorac Surg
, vol.57
, pp. 1395-1401
-
-
Smythe, W.R.1
Kaiser, L.R.2
Hwang, H.C.3
Amin, K.M.4
Pilewski, J.M.5
Eck, S.J.6
Wilson, J.M.7
Abelda, S.M.8
-
21
-
-
0028075655
-
Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component
-
21. Vile RG, Nelson JA, Castleden S, Chong H, Hart IR: Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component. Cancer Res 54:6228-6234, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 6228-6234
-
-
Vile, R.G.1
Nelson, J.A.2
Castleden, S.3
Chong, H.4
Hart, I.R.5
-
22
-
-
0028579733
-
Oncogenes and the strategy of growth factors
-
22. Baserga R: Oncogenes and the strategy of growth factors. Cell 79:927-930, 1994
-
(1994)
Cell
, vol.79
, pp. 927-930
-
-
Baserga, R.1
-
23
-
-
0029340302
-
Gene therapy using adeno virus carrying the herpes simplex-thymidine kinase gene to treat in vivo models of human malignant mesothelioma and lung cancer
-
23. Hwang HC, Smythe WR, Elshami AA, Kucharczuk JC, Amin KM, Williams JP, Litzky LA, Kaiser LR, Abelda SM: Gene therapy using adeno virus carrying the herpes simplex-thymidine kinase gene to treat in vivo models of human malignant mesothelioma and lung cancer. Am J Respir Cell Mol Biol 13:7-16, 1995
-
(1995)
Am J Respir Cell Mol Biol
, vol.13
, pp. 7-16
-
-
Hwang, H.C.1
Smythe, W.R.2
Elshami, A.A.3
Kucharczuk, J.C.4
Amin, K.M.5
Williams, J.P.6
Litzky, L.A.7
Kaiser, L.R.8
Abelda, S.M.9
-
24
-
-
0028124788
-
Expression of a thyroid hormone-responsive recombinant gene introduced into adult mice livers by replication-defective adenovirus can be regulated by endogenous thyroid hormone receptor
-
24. Hayashi Y, DePaoli AM, Burant CF, Refetoff S: Expression of a thyroid hormone-responsive recombinant gene introduced into adult mice livers by replication-defective adenovirus can be regulated by endogenous thyroid hormone receptor. J Biol Chem 269:23872-23875, 1993
-
(1993)
J Biol Chem
, vol.269
, pp. 23872-23875
-
-
Hayashi, Y.1
Depaoli, A.M.2
Burant, C.F.3
Refetoff, S.4
-
25
-
-
0028260891
-
Adenovirus-mediated transfer of human lipase complementary DNA to the gallbladder
-
25. Maeda H, Danel C, Crystal RG: Adenovirus-mediated transfer of human lipase complementary DNA to the gallbladder. Gastroenterology 106:1638-1644, 1994
-
(1994)
Gastroenterology
, vol.106
, pp. 1638-1644
-
-
Maeda, H.1
Danel, C.2
Crystal, R.G.3
-
26
-
-
0026782439
-
Wide-spread long-term gene transfer to mouse skeletal muscles and heart
-
26. Stratford-Perricaudet LD, Makeh I, Perricaudet M, Briand P: Wide-spread long-term gene transfer to mouse skeletal muscles and heart. J Clin Invest 90:626-630, 1992
-
(1992)
J Clin Invest
, vol.90
, pp. 626-630
-
-
Stratford-Perricaudet, L.D.1
Makeh, I.2
Perricaudet, M.3
Briand, P.4
-
27
-
-
0028168775
-
Direct in vivo gene transfer and expression in malignant cells using adenovirus vectors
-
27. Brody SL, Jaffe A, Han SK, Wersto RP, Crystal RG: Direct in vivo gene transfer and expression in malignant cells using adenovirus vectors. Hum Gene Ther 5:437-447, 1994
-
(1994)
Hum Gene Ther
, vol.5
, pp. 437-447
-
-
Brody, S.L.1
Jaffe, A.2
Han, S.K.3
Wersto, R.P.4
Crystal, R.G.5
-
28
-
-
0030054785
-
Adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase in an ascites model of human breast cancer
-
28. Yee D, McGuire SE, Brunner N, Kozelsky TW, Allred DC, Chen S-H, Woo SLC: Adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase in an ascites model of human breast cancer. Hum Gene Ther 7:1251-1257, 1996
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1251-1257
-
-
Yee, D.1
McGuire, S.E.2
Brunner, N.3
Kozelsky, T.W.4
Allred, D.C.5
Chen, S.-H.6
Woo, S.L.C.7
-
29
-
-
0028116059
-
Gene therapy for carcinoembryonic antigen-producing human lung cancer cells by cell type-specific expression of herpes simplex virus thymidine kinase gene
-
29. Osaki T, Tanio Y, Tachibana I, Hosoe S, Kumagai T, Kawase I, Oikawa S, Kishimoto T: Gene therapy for carcinoembryonic antigen-producing human lung cancer cells by cell type-specific expression of herpes simplex virus thymidine kinase gene. Cancer Res 54:5258-5261, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 5258-5261
-
-
Osaki, T.1
Tanio, Y.2
Tachibana, I.3
Hosoe, S.4
Kumagai, T.5
Kawase, I.6
Oikawa, S.7
Kishimoto, T.8
-
30
-
-
0028045168
-
Strategy for achieving selective killing of carcinomas
-
30. Garver RI, Goldsmith KT, Rodu B, Hu P-C, Sorscher EJ: Strategy for achieving selective killing of carcinomas. Gene Ther 1:46-50, 1994
-
(1994)
Gene Ther
, vol.1
, pp. 46-50
-
-
Garver, R.I.1
Goldsmith, K.T.2
Rodu, B.3
Hu, P.-C.4
Sorscher, E.J.5
-
31
-
-
0028148134
-
Directed enzyme pro-drug gene therapy for pancreatic cancer in vivo
-
31. DiMaio JM, Clary BM, Via DF, Coveney E, Pappas TN, Lyerly HK: Directed enzyme pro-drug gene therapy for pancreatic cancer in vivo. Surgery 116:205-213, 1994
-
(1994)
Surgery
, vol.116
, pp. 205-213
-
-
Dimaio, J.M.1
Clary, B.M.2
Via, D.F.3
Coveney, E.4
Pappas, T.N.5
Lyerly, H.K.6
-
32
-
-
0028127077
-
Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene and confer sensitivity of human breast cancer cells to gancyclovir
-
32. Manome Y, Abe M, Hagen MF, Fine HA, Kufe DW: Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene and confer sensitivity of human breast cancer cells to gancyclovir. Cancer Res 54:5408-5413, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 5408-5413
-
-
Manome, Y.1
Abe, M.2
Hagen, M.F.3
Fine, H.A.4
Kufe, D.W.5
-
33
-
-
0029018605
-
Gene therapy for hepatoma cells using a retrovirus vector carrying herpes simplex virus thymidine kinase gene under the control of human α-fetoprotein gene promoter
-
33. Ido A, Nakata K, Kato Y, Nakao K, Murata K, Fujita M, Ishii N, Tamaoki T, Shiku H, Nagataki S: Gene therapy for hepatoma cells using a retrovirus vector carrying herpes simplex virus thymidine kinase gene under the control of human α-fetoprotein gene promoter. Cancer Res 55:3105-3109, 1995
-
(1995)
Cancer Res
, vol.55
, pp. 3105-3109
-
-
Ido, A.1
Nakata, K.2
Kato, Y.3
Nakao, K.4
Murata, K.5
Fujita, M.6
Ishii, N.7
Tamaoki, T.8
Shiku, H.9
Nagataki, S.10
-
34
-
-
0027495704
-
The adenovirus-mediated delivery of a reporter gene permits the assessment of androgen receptor function in genital skin fibroblast cultures
-
34. McPhaul MJ, Deslypere J-P, Allman DR, Gerard RD: The adenovirus-mediated delivery of a reporter gene permits the assessment of androgen receptor function in genital skin fibroblast cultures. J Biol Chem 269:26063-26066, 1993
-
(1993)
J Biol Chem
, vol.269
, pp. 26063-26066
-
-
McPhaul, M.J.1
Deslypere, J.-P.2
Allman, D.R.3
Gerard, R.D.4
-
35
-
-
0029013217
-
Inflammation-induced recombinant protein expression in vivo using promoters from acute-phase protein genes
-
35. Varley AW, Coulthard MG, Meidell RS, Gerard RD: Inflammation-induced recombinant protein expression in vivo using promoters from acute-phase protein genes. Proc Natl Acad Sci USA 92:5346-5350, 1995
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5346-5350
-
-
Varley, A.W.1
Coulthard, M.G.2
Meidell, R.S.3
Gerard, R.D.4
-
36
-
-
0028808656
-
Adenovirus-mediated gene therapy of hepatocellular carcinoma using cancer-specific gene expression
-
36. Kaneko S, Hallenbeck P, Kotani T, Nakabayashi H, McGarrity G, Tamaoki T, Anderson WF, Chiang YL: Adenovirus-mediated gene therapy of hepatocellular carcinoma using cancer-specific gene expression. Cancer Res 55:5283-5287, 1995
-
(1995)
Cancer Res
, vol.55
, pp. 5283-5287
-
-
Kaneko, S.1
Hallenbeck, P.2
Kotani, T.3
Nakabayashi, H.4
McGarrity, G.5
Tamaoki, T.6
Anderson, W.F.7
Chiang, Y.L.8
-
37
-
-
0029927495
-
Adenovirus-mediated prodrug gene therapy for carcinoembryonic antigen-producing human gastric carcinoma cells in vitro
-
37. Tanaka T, Kanai F, Okabe S, Yoshida Y, Wakimoto H, Hamada H, Shiratori Y, Lan K-H, Ishitobi M, Omata M: Adenovirus-mediated prodrug gene therapy for carcinoembryonic antigen-producing human gastric carcinoma cells in vitro. Cancer Res 56:1341-1345, 1996
-
(1996)
Cancer Res
, vol.56
, pp. 1341-1345
-
-
Tanaka, T.1
Kanai, F.2
Okabe, S.3
Yoshida, Y.4
Wakimoto, H.5
Hamada, H.6
Shiratori, Y.7
Lan, K.-H.8
Ishitobi, M.9
Omata, M.10
-
38
-
-
0011208794
-
Development of an adenoviral vector system which confers gene expression which is specific for neoplastic cells
-
38. Chung I, Crystal RG, Deisseroth AB: Development of an adenoviral vector system which confers gene expression which is specific for neoplastic cells. Proc Am Assoc Cancer Res 37:347, 1996
-
(1996)
Proc Am Assoc Cancer Res
, vol.37
, pp. 347
-
-
Chung, I.1
Crystal, R.G.2
Deisseroth, A.B.3
|