Molecular structure and functional role of vascular tight junctions

Trends in Cardiovascular Medicine

Volumn 9, Issue 6, 1999, Pages 147-152

  Bazzoni, Gianfranco ^a   Estrada, Ofelia Maria Martínez ^a   Dejana, Elisabetta ^a,b  

^a Laboratory of Molecular Biology   (Italy)

^b Univ Studi D   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOGENESIS; CELL MEMBRANE PERMEABILITY; CELL POLARITY; CYTOCHEMISTRY; ENDOTHELIUM; EPITHELIUM CELL; HEART MUSCLE CELL; HUMAN; IN VITRO STUDY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; REVIEW; TIGHT JUNCTION;

CARDIOVASCULAR PHYSIOLOGY; CELL ADHESION; CELL MEMBRANE PERMEABILITY; ENDOTHELIUM; HOMEOSTASIS; HUMANS; MEMBRANE PROTEINS; SIGNAL TRANSDUCTION; TIGHT JUNCTIONS; URINARY TRACT PHYSIOLOGY;

EID: 0032764006     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1050-1738(99)00022-5     Document Type: Review

References (52)

1. Anderson J.M., Van Itallie C.M. Tight junctions and the molecular basis for regulation of paracellular permeability. Am J Pathol. 269:1995;G465-G475.
2. Angst B.D., Khan L.U., Severs N.J.et al. Dissociated spatial patterning of gap junctions and cell adhesion junctions during postnatal differentiation of ventricular myocardium. Circ Res. 80:1997;88-94.
3. Balda M.S., Anderson J.M. Two classes of tight junctions are revealed by ZO-1 isoforms. Am J Physiol. 264:1993;C918-C924.
4. Balda M.S., Gonzalez-Mariscal L., Matter K., Cerijido M., Anderson J.M. Assembly of the tight junction. the role of diacylglycerol J Cell Biol. 123:1993;293-302.
5. Behrens J., Birchmeier W., Goodman S.L., Imhof B.A. Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1. mechanistic aspects and identification of the antigen as a component related to uvomorulin J Cell Biol. 101:1985;1307-1315.
6. Blum M.S., Toninelli E., Anderson J.M.et al. Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines. Am J Physiol. 273:1997;H286-H294.
7. Carmeliet P., Lampugnani M.G., Moons L.et al. Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis. Cell. 98:1999;147-157.
8. Chen Y., Merzdorf C., Paul D.L., Goodenough D.A. COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos. J Cell Biol. 138:1997;891-899.
9. Citi S., Sabanay H., Jakes R., Geiger B., Kendrick-Jones J. Cingulin, a new peripheral component of tight junctions. Nature. 333:1988;272-276.
10. Corada M., Mariotti M., Thurston G.et al. VE-cadherin is an important determinant of microvascular permeability in vivo. Proc Natl Acad Sci U S A. 96:1999;9815-9820.
11. Denker B.M., Nigam S.K. Molecular structure and assembly of the tight junction. Am J Physiol. 274:1998;F1-F9.
12. Denker B.M., Saha C., Khawaja S., Nigam S.K. Involvement of a heterotrimeric G protein alpha subunit in tight junction biogenesis. J Biol Chem. 271:1996;25,750-25,753.
13. Fanning A.S., Jameson B.J., Jesaitis L.A., Anderson J.M. The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J Biol Chem. 273:1998;29,745-29,753.
14. Farquhar M.G., Palade G.E. Junctional complexes in various epithelia. J Cell Biol. 17:1963;375-412.
15. Furuse M., Hirase T., Itoh M.et al. Occludin. a novel integral membrane protein localizing at tight junctions J Cell Biol. 123:1993;1777-1788.
16. Furuse M., Itoh M., Hirase T.et al. Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junction. J Cell Biol. 127:1994;1617-1626.
17. Furuse M., Fujita K., Hiiragi T., Fujimoto K., Tsukita S. Claudin-1 and -2. novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin J Cell Biol. 141:1998;1539-1550. a.
18. Furuse M., Sasaki H., Fujimoto K., Tsukita S. A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol. 143:1998;391-401. b.
19. Giepmans B.N., Moolenaar W.H. The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein. Curr Biol. 8:1998;931-934.
20. Gumbiner B., Lowenkopf T., Apatira D. Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1. Proc Natl Acad Sci U S A. 88:1991;3460-3464.
21. Haskins J., Gu L., Wittchen E.S., Hibbard J., Stevenson B.R. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J Cell Biol. 141:1998;199-208.
22. Howarth A.G., Hughes M.R., Stevenson B.R. Detection of the tight junction-associated protein ZO-1 in astrocytes and other nonepithelial cell types. Am J Pathol. 262:1992;C461-C469.
23. Itoh M., Yonemura S., Nagafuchi A., Tsukita S. A 220-kD undercoat-constitutive protein. its specific localization at cadherin-based cell-cell adhesion sites J Cell Biol. 115:1991;1449-1462.
24. Itoh M., Nagafuchi A., Yonemura S., Kitani-Yasuda T., Tsukita S., Tsukita S. The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells. cDNA cloning and immunoelectron microscopy J Cell Biol. 121:1993;491-502.
25. Itoh M., Nagafuchi A., Moroi S., Tsukita S. Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments. J Cell Biol. 138:1997;181-192.
26. Itoh M., Morita K., Tsukita S. Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and alpha catenin. J Biol Chem. 274:1999;5981-5986.
27. Jesaitis L.A., Goodenough D.A. Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein. J Cell Biol. 124:1994;949-961.
28. Jou T.S., Schneeberger E.E., Nelson W.J. Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases. J Cell Biol. 142:1998;101-115.
29. Kawachi H., Kurihara H., Topham P.S.et al. Slit diaphragm-reactive nephritogenic MAb 5-1-6 alters expression of ZO-1 in rat podocytes. Am J Physiol. 273:1997;F984-F993.
30. Keon B.H., Schafer S.S., Kuhn C., Grund C., Franke W.W. Symplekin, a novel type of tight junction plaque protein. J Cell Biol. 134:1996;1003-1018.
31. Kurihara H., Anderson J.M., Farquhar M.G. Diversity among tight junctions in rat kidney. glomerular slit diaphragms and endothelial junctions express only one isoform of the tight junction protein ZO-1 Proc Natl Acad Sci U S A. 89:1992;7075-7079.
32. Lampugnani M.G., Dejana E. Interendothelial junctions. structure, signalling and functional roles Curr Opin Cell Biol. 9:1997;674-682.
33. Madara J.L. Regulation of the movement of solutes across tight junctions. Annu Rev Physiol. 60:1998;143-159.
34. Martin-Padura I., Lostaglio S., Schneemann M.et al. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol. 142:1998;117-127.
35. Matter K., Balda M.S. Biogenesis of tight junctions. the C-terminal domain of occludin mediates basolateral targeting J Cell Sci. 111:1998;511-519.
36. Mitic L.L., Anderson J.M. Molecular architecture of tight junctions. Annu Rev Physiol. 60:1998;121-142.
37. Ohsugi M., Larue L., Schwarz H., Kemler R. Cell-junctional and cytoskeletal organization in mouse blastocysts lacking E-cadherin. Dev Biol. 185:1997;261-271.
38. Rajasekaran A.K., Hojo M., Huima T., Rodriguez-Boulan E. Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctions. J Cell Biol. 132:1996;451-463.
39. Saitou M., Fujimoto K., Doi Y.et al. Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J Cell Biol. 141:1998;397-408.
40. Sakakibara A., Furuse M., Saitou M., Ando-Akatsuka Y., Tsukita S. Possible involvement of phosphorylation of occludin in tight junction formation. J Cell Biol. 137:1997;1393-1401.
41. Schnabel E., Anderson J.M., Farquhar M.G. The tight junction protein ZO-1 is concentrated along slit diaphragms of the glomerular epithelium. J Cell Biol. 111:1990;1255-1263.
42. Staddon J.M., Herrenknecht K., Smales C., Rubin L.L. Evidence that tyrosine phosphorylation may increase tight junction permeability. J Cell Sci. 108:1995;609-619.
43. Stevenson B.R., Keon B.H. The tight junction. morphology to molecules Annu Rev Cell Dev Biol. 14:1998;89-109.
44. Stevenson B.R., Siliciano J.D., Mooseker M.S., Goodenough D.A. Identification of ZO-1. a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia J Cell Biol. 103:1986;755-766.
45. Toyofuku T., Yabuki M., Otsu K., Kuzuya T., Hori M., Tada M. Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes. J Biol Chem. 273:1998;12,725-12,731.
46. Van Itallie C.M., Anderson J.M. Occludin confers adhesiveness when expressed in fibroblasts. J Cell Sci. 110:1997;1113-1121.
47. Weber E., Berta G., Tousson A.et al. Expression and polarized targeting of a rab3 isoform in epithelial cells. J Cell Biol. 125:1994;583-594.
48. Wong V., Gumbiner B.M. A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier. J Cell Biol. 136:1997;399-409.
49. Woods D.F., Hough C., Peel D., Callaini G., Bryant P.J. Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia. J Cell Biol. 134:1996;1469-1482.
50. Yamamoto T., Harada N., Kano K.et al. The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells. J Cell Biol. 139:1997;785-795.
51. Zahraoui A., Joberty G., Arpin M.et al. A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells. J Cell Biol. 124:1994;101-115.
52. Zhong Y., Saitoh T., Minase T., Sawada N., Enomoto K., Mori M. Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2. J Cell Biol. 120:1993;477-483.