Visual dysfunction in patients receiving vigabatrin: Clinical and electrophysiologic findings

Neurology

Volumn 53, Issue 9, 1999, Pages 2082-2087

  Miller, N R ^a,c   Johnson, M A ^b   Paul, S R ^a   Girkin, C A ^a   Perry, J D ^a   Endres, M ^a   Krauss, G L ^d  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d NONE

Author keywords

Electroretinogram; Perimetry; Seizures; Vigabatrin; Visual fields; Aminobutyric acid

Indexed keywords

4 AMINOBUTYRIC ACID; CARBAMAZEPINE; LAMOTRIGINE; PHENYTOIN; PRIMIDONE; VALPROIC ACID; VIGABATRIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COLOR VISION; CONTROLLED STUDY; ELECTRORETINOGRAM; EPILEPSY; FEMALE; HUMAN; MALE; PERIMETRY; PRIORITY JOURNAL; VISUAL ACUITY; VISUAL DISORDER; VISUAL FIELD;

EID: 0032763649     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.53.9.2082     Document Type: Article

References (21)

1. Ben-Menschem E. Vigabatrin. Epilepsia 1995;36(suppl 2): S95-S104.
2. French JA, Mosier M, Walker S, Sommerville K, Sussman N. A double-blind placebo-controlled study of vigabatrin three g/day in patients with uncontrolled complex partial seizures: Vigabatrin Protocol 024 Investigative Consort. Neurology 1996;46:54-61.
3. Marson AG, Kadir ZA, Hutton JL, Chadwick DW. The new antiepileptic drugs: a systemic review of their efficacy and tolerability. Epilepsia 1997;38:859-880.
4. Petroff OA, Rothman DL, Behar KL, Collins TL, Mattson RH. Human brain GABA levels rise rapidly after initiation of vigabatrin therapy. Neurology 1996;47:1567-1571.
5. Ben-Menachem E, French J. Vigabatrin. In: Engel, J, Pedley TA eds. Epilepsy: a comprehensive textbook. Philadelphia: Lippincott-Raven, 1998:1609-1618.
6. Fisher RS, Kerrigan JF. Vigabatrin: toxicity. In: Levy RH, Mattson RH, Meldrum BS, eds. Antiepileptic drugs. 4th ed. New York: Raven Press, 1995:931-939.
7. Elke T, Talbot JF, Lawden MC. Severe persistent visual field constriction associated with vigabatrin. BMJ 1997;314:180-181.
8. Wilson EA, Brodie MJ. Severe persistent visual field constriction associated with vigabatrin. BMJ 1997;314:1693.
9. Wong IC, Mawer GE, Sander JW. Severe persistent visual field constriction associated with vigabatrin. BMJ 1997;314: 1693-1694.
10. Blackwell N, Hayllar J, Kelly G. Severe persistent visual field constriction associated with vigabatrin. BMJ 1997;314:1694.
11. Harding GF. Severe persistent visual field constriction associated with vigabatrin. BMJ 1997;314:1694.
12. Kramer G, Scollo-Lavizzari G, Jallon P, et al. Vigabatrin-associated bilateral concentric visual field defects in four patients. Epilepsia 1997;38(suppl 8):179.
13. Krauss GL, Johnson MA, Miller NR. Vigabatrin-associated retinal cone system dysfunction: electroretinogram and ophthalmologic findings. Neurology 1998;50:614-618.
14. Zackon DH, Guberman A, Racette L, et al. Vigabatrin and visual loss. Presented at the North American Neuro-Ophthalmology Society Meeting, Orlando, FL, March 22-26, 1998.
15. Lawden MC, Eke T, Degg C, et al. Visual field constriction associated with vigabatrin treatment. Neuro-Ophthalmology 1998;20:17.
16. Kalvianen R, Nousiainen I, Mantyjarvi M, et al. Initial vigabatrin monotherapy is associated with increased risk of visual field constriction: a comparative follow-up study with patients on initial carbamazepine monotherapy and healthy controls. Epilepsia 1998;39(suppl 6):72.
17. Ruether K, Pung T, Kellner U, et al. Electrophysiologic evaluation of a patient with peripheral visual field constriction associated with vigabatrin. Arch Ophthalmol 1998;116:817-819.
18. Diabetic Retinopathy Study. Manual of operations. Baltimore: Diabetic Retinopathy Study Coordinating Center, 1972.
19. Pourcho RG. Uptake of [H3]glycine and [HS]GABA by amacrine cells in the cat retina. Brain Res 1980;198:33-46.
20. Euler T, Wässle H. Different contribution of GABA(A) and GABA(C) receptors to rod and cone bipolar cells in the rat retinal slice. Invest Ophthalmol Vis Sci 1997;38:S1141.
21. C receptor antagonists have opposite effects on the b-wave of ERG in rat retina. Invest Ophthalmol Vis Sci 1998;39:S980.