New approaches to rational drug design

Pharmacology and Therapeutics

Volumn 84, Issue 3, 1999, Pages 327-332

  Farber, Gregory K ^a  

^a 108 Althouse Laboratory   (United States)

Author keywords

Co solvents; MIF, migration inhibitory factor; Nonaqueous solvents; Organic solvents; Protein crystallography; SAR, structure activity relationship; Structural genomics

Indexed keywords

CHYMOTRYPSIN; DIHYDROFOLATE REDUCTASE; DIHYDROFOLIC ACID; ISOMERASE; MACROPHAGE MIGRATION INHIBITION FACTOR; METHOTREXATE; SUBTILISIN;

BINDING SITE; CRYSTAL STRUCTURE; DRUG DESIGN; GENE STRUCTURE; HUMAN; IN VITRO STUDY; METHODOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; REVIEW; SEQUENCE ANALYSIS; TECHNIQUE; THERMODYNAMICS;

BINDING SITES; DRUG DESIGN; PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032763627     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(99)00039-X     Document Type: Review

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