Effects of kappa opioid agonists on the discriminative stimulus effects of cocaine in rhesus monkeys

Experimental and Clinical Psychopharmacology

Volumn 7, Issue 4, 1999, Pages 307-317

  Negus, S Stevens ^a   Mello, Nancy K ^a  

^a MCLEAN HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; COCAINE; ETHYLKETAZOCINE; ETICLOPRIDE; KAPPA OPIATE RECEPTOR AGONIST; NALOXONE;

ANIMAL EXPERIMENT; ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; DISCRIMINATION LEARNING; DISCRIMINATIVE STIMULUS; DOPAMINERGIC SYSTEM; DOSE RESPONSE; DRUG DISCRIMINATION; NONHUMAN; RHESUS MONKEY;

EID: 0032763070     PISSN: 10641297     EISSN: None     Source Type: Journal    
DOI: 10.1037/1064-1297.7.4.307     Document Type: Article

References (56)

1. Broadbent, J., Gaspard, T. M., & Dworkin, S. I. (1995). Assessment of the discriminative stimulus effects of cocaine in the rat: Lack of interaction with opioids. Pharmacology, Biochemistry and Behavior, 51, 379-385.
2. Butelman, E. R., Negus, S. S., Ai, Y., de Costa, B. R., & Woods, J. H. (1993). Kappa opioid antagonist effects of systemically administered nor-binaltorphimine (nor-BNI) in a thermal antinociception assay in rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics, 257, 1269-1276.
3. Callahan, P. M., & Cunningham, K. A. (1995). Modulation of the discriminative stimulus properties of cocaine by 5-HT1B and 5-HT2C receptors. Journal of Pharmacology and Experimental Therapeutics, 274, 1414-1424.
4. Colpaert, F. C., Niemegeers, C. J. E., & Janssen, P. A. J. (1979). Discriminative stimulus properties of cocaine: Neuropharmacological characteristics as derived from stimulus generalization experiments. Pharmacology Biochemistry and Behavior, 10, 535-546.
5. Crawford, C. A., McDougall, S. A., Bolanos, C. A., Hall, S., & Berger, S. P. (1995). The effects of the kappa agonist U-50,488 on cocaine-induced conditioned and unconditioned behaviors and Fos immunoreactivity. Psychopharmacology, 120, 392-399.
6. Cui, Y., Lee, T., & Wang, L. C. (1994). Species differences in the modulatory effects of kappa agonists on 5-HT release from ground squirrel and rat hippocampus. Neuroscience Letters, 175, 126-128.
7. Devine, D. P., Leone, P., Pocock, D., & Wise, R. A. (1993). Differential involvement of ventral tegmental mu, delta and kappa opioid receptors in modulation of basal mesolimbic dopamine release: In vivo microdialysis studies. Journal of Pharmacology and Experimental Therapeutics, 266, 1236-1246.
8. DiChiara, G., & Imperato, A. (1988). Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats. Journal of Pharmacology and Experimental Therapeutics, 244, 1067-1080.
9. Donzanti, B. A., Althaus, J. S., Payson, M. M., & VonVoigtlander, P. F. (1992). Kappa agonist-induced reduction in dopamine release: Site of action and tolerance. Research Communications in Chemical Pathology and Pharmacology, 78, 193-210.
10. Emmerson, P. J., Liu, M-R., Woods, J. H., & Medzihradsky, F. (1994). Binding affinity and selectivity of opioids at mu, celta and kappa receptors in monkey brain membranes. Journal of Pharmacology and Experimental Therapeutics, 271, 1630-1637.
11. Foltin, R. W., & Fischman, M. W. (1992). The cardiovascular and subjective effects of intravenous cocaine and morphine combinations in humans. Journal of Pharmacology and Experimental Therapeutics, 261, 623-632.
12. Glick, S. D., Maisonneuve, I. M., Raucci, J., & Archer, S. (1995). Kappa opioid inhibition of morphine and cocaine self-administration in rats. Brain Research, 681, 147-152.
13. Heidbreder, C. A., Babovic-Vuksanovic, D., Shoaib, M., & Shippenberg, T. (1995). Development of behavioral sensitization to cocaine: Influence of kappa opioid receptor agonists. Journal of Pharmacology and Experimental Therapeutics, 275, 150-163.
14. Johanson, C. E. (1978). Effects of intravenous cocaine, diethylpropion, d-amphetamine and perphenazine on responding maintained by food delivery and shock avoidance in rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics, 204, 118-129.
15. Johanson, C. E., & Fischman, M. W. (1989). The pharmacology of cocaine related to its abuse. Pharmacological Reviews, 41, 3-52.
16. Kleven, M. S., Anthony, E. W., & Woolverton, W. L. (1990). Pharmacological characterization of the discriminative stimulus effects of cocaine in rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics, 254, 312-317.
17. Kleven, M. S., & Woolverton, W. L. (1990). Effects of continuous infusions of SCH 23390 on cocaine- or food-maintained behavior in rhesus monkeys. Behavioral Pharmacology, 1, 365-373.
18. Koe, B. K. (1976). Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain. Journal of Pharmacology and Experimental Therapeutics, 199, 649-661.
19. Koob, G. F., & Bloom, F. E. (1988). Cellular and molecular mechanisms of drug dependence. Science, 24, 715-723.
20. Kuhar, M. J., Ritz, M. C., & Boja, J. W. (1991). The dopamine hypothesis of the reinforcing properties of cocaine. Trends in Neurosciences, 14, 299-302.
21. Kuzmin, A. V., Semenova, S., Gerrits, M. A. F. M., Zvartau, E. E., & Van Ree, R. J. M. (1997). Kappa-opioid receptor agonist U50,488H modulates cocaine and morphine self-administration in drug-naive rats and mice. European Journal of Pharmacology, 321, 265-271.
22. Line, S. W., Markowitz, H., Morgan, K. N., & Strong, S. (1989). Evaluation of attempts to enrich the environment of single-caged non-human primates. In J. W. Driscoll (Ed.), Animal care and use in behavioral research: Regulations, issues, and applications (pp. 103-117). Beltsville, MD: National Agricultural Library.
23. Maisonneuve, I. M., Archer, S., & Glick, S. D. (1994). U50,488 a K opioid receptor agonist, attenuates cocaine-induced increases in extracellular dopamine in the nucleus accumbens of rats. Neuroscience Letters, 181, 57-60.
24. Mansour, A., Fox, C. A., Burke, S., Meng, F., Thompson, R. C., Akil, H., & Watson, S. J. (1994). Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: An in situ hybridization study. Journal of Comparative Neurology, 350, 412-438.
25. Mansour, A., Khachaturian, H., Lewis, M. E., Akil, H., & Watson, S. J. (1987). Autoradiographic differentiation of mu, delta and kappa opioid receptors in rat forebrain and midbrain. Journal of Neuroscience, 7, 2445-2464.
26. Mansour, A., Khachaturian, H., Lewis, M. E., Akil, H., & Watson, S. J. (1988). Anatomy of CNS opioid receptors. Trends in Neurosciences, 11, 308-314.
27. Mello, N. K., & Negus, S. S. (1996). Preclinical evaluation of pharmacotherapies for treatment of cocaine and opiate abuse using drug self-administration procedures. Neuropsychopharmacology, 14, 375-424.
28. Mello, N. K., & Negus, S. S. (1998). Effects of kappa opioid agonists on cocaine- and food-maintained responding by rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics, 286, 812-824.
29. Mello, N. K., Negus, S. S., Lukas, S. E., Mendelson, J. H., Sholar, J. W., & Drieze, J. (1995). A primate model of polydrug abuse: Cocaine and heroin combinations. Journal of Pharmacology and Experimental Therapeutics, 274, 1325-1337.
30. Mendelson, J. H., & Mello, N. K. (1996). Drug therapy: Management of cocaine abuse and dependence. New England Journal of Medicine, 334, 965-972.
31. National Institute on Drug Abuse. (1998). Epidemiologic trends in drug abuse: Vol. I. Highlights and executive summary (NIH Publication No. 98-4300, p. 79). Washington, DC: U.S. Department of Health and Human Services.
32. Negus, S. S., Burke, T. F., Medzilhradsky, F., & Woods, J. H. (1993). Effects of opioid agonists selective for mu, kappa and delta opioid receptors on schedule-controlled responding in rhesus monkeys: Antagonism by quadazocine. Journal of Pharmacology and Experimental Therapeutics, 267, 896-903.
33. Negus, S. S., Gatch, M. B., & Mello, N. K. (1998). Effects of mu opioid agonists alone and in combination with cocaine and d-amphetamine in rhesus monkeys trained to discriminate cocaine. Neuropsychopharmacology, 18, 325-338.
34. Negus, S. S., Mello, N. K., Lamas, X., & Mendelson, J. H. (1996). Acute and chronic effects of flupenthixol on the discriminative stimulus and reinforcing effects of cocaine in rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics, 278, 879-890.
35. Negus, S. S., Mello, N. K., Portoghese, P. S., & Lin, C-E. (1997). Effects of kappa opioids on cocaine self-administration by rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics, 282, 44-55.
36. Pakarinen, E. D., Woods, J. H., & Moerschbaecher, J. M. (1995). Repeated acquisition of behavioral chains in squirrel monkeys: Comparisons of a mu, kappa and delta opioid agonist. Journal of Pharmacology and Experimental Therapeutics, 272, 552-559.
37. Pfeiffer, A., Branti, V., Herz, A., & Emrich, H. M. (1986). Psychotomimesis mediated by k opiate receptors. Science, 233, 774-776.
38. Powell, K. R., & Holtzman, S. G. (in press). Modulation of the discriminative stimulus effects of d-amphetamine by mu and kappa opioids in squirrel monkeys. Pharmacology, Biochemistry and Behavior.
39. Reece, P. A., Sedman, A. J., Rose, S., Wright, D. S., Dawkins, R., & Rajagopalanm, R. (1994). Diuretic effects, pharmacokinetics, and safety of a new centrally acting kappa-opioid agonist (CI-977) in humans. Journal of Clinical Pharmacology, 34, 1126-1132.
40. Reith, M. E. A. (1988). Cocaine receptors on monoamine transporters and sodium channels. In D. A. K. Clouet and R. Brown (Eds.), Mechanisms of cocaine abuse and toxicity (NIDA Research Monograph No. 88, pp. 23-43). Rockville, MD: National Institute on Drug Abuse.
41. Rimoy, G. H., Bhaskar, N. K., Wright, D. M., & Rubin, P. C. (1991). Mechanism of diuretic action of spiradoline (U-62066E) - A kappa opioid receptor agonist in the human. Journal of Clinical Pharmacology, 32, 611-615.
42. Ritz, M. C., Lamb, R. J., Goldberg, S. R., & Kuhar, M. J. (1987). Cocaine receptors in dopamine transporters are related to self-administration of cocaine. Science, 237, 1219-1223.
43. Shippenberg, T. S., LeFevour, A., & Heidbreder, C. H. (1996). κ-opioid receptor agonists prevent sensitization to the conditioned rewarding effects of cocaine. Journal of Pharmacology and Experimental Therapeutics, 276, 545-554.
44. Spanagel, R., Herz, A., & Shippenberg, T. S. (1992). Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Procedures of the National Academy of Science, 89, 2046-2050.
45. Spealman, R. D. (1995). Noradrenergic involvement in the discriminative stimulus effects of cocaine in squirrel monkeys. Journal of Pharmacology and Experimental Therapeutics, 275, 53-62.
46. Spealman, R. D., & Bergman, J. (1992). Modulation of the discriminative stimulus effects of cocaine by mu and kappa opioids. Journal of Pharmacology and Experimental Therapeutics, 261, 607-615.
47. Spealman, R. D., & Bergman, J. (1994). Opioid modulation of the discriminative stimulus effects of cocaine: Comparison of μ, κ and ∂ agonists in squirrel monkeys discriminating low doses of cocaine. Behavioral Pharmacology, 5, 21-31.
48. Spealman, R. D., Bergman, J., Madras, B. K., & Melia, K. F. (1991). Discriminative-stimulus effects of cocaine in squirrel monkeys: Involvement of dopamine receptor subtypes. Journal of Pharmacology and Experimental Therapeutics, 258, 945-953.
49. Spealman, R. D., Madras, B. K., & Bergman, J. (1989). Effects of cocaine and related drugs in nonhuman primates: II. Stimulant effects on schedule-controlled behavior. Journal of Pharmacology and Experimental Therapeutics, 251, 142-149.
50. Steiner, H., & Gerfen, C. R. (1995). Dynorphin opioid inhibition of cocaine-induced, D1 dopamine receptor-mediated immediateearly gene expression in the striatum. Journal of Comparative Neurology, 353, 200-212.
51. Suzuki, T., Mori, T., Tsuji, M., Maeda, J., Kishimoto, Y., Misawa, M., & Nagase, H. (1997). Differential effects of mu-, delta- and kappa-opioid receptor agonists on the discriminative stimulus properties of cocaine in rats. European Journal of Pharmacology, 324, 21-29.
52. Suzuki, T., Shiozaki, Y., Masukawa, Y., Misawa, M., & Nagase, H. (1992). The role of mu- and kappa-opioid receptors in cocaine-induced conditioned place preference. Japanese Journal of Pharmacology, 58, 435-442.
53. Ukai, M., Mizutani, M., & Kameyama, T. (1994). Opioid peptides selective for receptor types modulate cocaine-induced behavioral responses in mice. Yakubutsu Seishin Kodo, 14, 153-159.
54. Werling, L. L., Brown, S. R., & Cox, B. M. (1987). Opioid receptors regulation of the release of norepinephrine in brain. Neuropharmacology, 26, 987-996.
55. Woolfolk, D. R., & Holtzman, S. G. (1997). μ-, δ- and ι-opioid receptor agonists do not alter the discriminative stimulus effects of cocaine or d-amphetamine in rats. Drug and Alcohol Dependence, 48, 209-220.
56. Woolverton, W. L., & Johnson, K. M. (1992). Neurobiology of cocaine abuse. Trends in Pharmacological Science, 13, 193-200.