Use of Herpesvirus saimiri-immortalized macaque CD4+ T cell clones as stimulators and targets for assessment of CTL responses in macaque/AIDS models

Journal of Immunological Methods

Volumn 230, Issue 1-2, 1999, Pages 47-58

  Kumar, Anil ^a   Stipp, Heather L ^a   Sheffer, Darlene ^a   Narayan, Opendra ^a  

^a Univ K   (United States)

Author keywords

CD4+ T cells; CTL; Herpesvirus saimiri; Macaque

Indexed keywords

CD4 ANTIGEN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; HERPES VIRUS SAIMIRI; LYMPHOCYTE ACTIVATION; MACACA; NONHUMAN; PRIORITY JOURNAL;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANIMALS; ANTIGENS, CD; ANTIGENS, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; CELL TRANSFORMATION, VIRAL; CHIMERA; CLONE CELLS; CYTOTOXICITY TESTS, IMMUNOLOGIC; DISEASE MODELS, ANIMAL; HERPESVIRUS 2, SAIMIRIINE; HIV; HIV ANTIGENS; HUMANS; INTERLEUKIN-2; MACACA NEMESTRINA; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; T-LYMPHOCYTES, CYTOTOXIC;

ANIMALIA; HERPES; HERPESVIRIDAE; HUMAN IMMUNODEFICIENCY VIRUS; MACACA NEMESTRINA; PRIMATES; SAIMIRI; SAIMIRIINE HERPESVIRUS 2; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS; SIMIAN-HUMAN IMMUNODEFICIENCY VIRUS; SUS SCROFA;

EID: 0032760197     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(99)00123-4     Document Type: Article

References (22)

1. Bauer M., Lucchiari-Hartz M., Fickenscher H., Eichmann K., McKeating J., Meyerhans A. Herpesvirus saimiri-transformed human CD4+ T-cell lines: an efficient target cell system for the analysis of human immunodeficiency virus-specific cytotoxic CD8+ T-lymphocyte activity. J. Virol. 72:1998;1627.
2. Biesinger B., Muller-Fleckenstein I., Simmer B., Lang G., Wittmann S., Platzer E., Desrosiers R.C., Fleckenstein B. Stable growth transformation of human T lymphocytes by Herpesvirus saimiri. Proc. Natl. Acad. Sci. U. S. A. 89:1992;3116.
3. Broker B.M., Tsygankov A.Y., Muller-Fleckenstein I., Guse A.H., Chitaev N.A., Biesinger B., Fleckenstein B., Emmrich F. Immortalization of human T cell clones by Herpesvirus saimiri. Signal transduction analysis reveals functional CD3, CD4, and IL-2 receptors. J. Immunol. 151:1993;1184.
4. Dorrell L., Dong T., Ogg G.S., Lister S., McAdam S., Rostron T., Conlon C., McMichael A.J., Rowland-Jones S.L. Distinct recognition of non-clade B human immunodeficiency virus type 1 epitopes by cytotoxic T lymphocytes generated from donors infected in Africa. J. Virol. 73:1999;1708.
5. Dyer W.B., Ogg G.S., Demoitie M.A., Jin X., Geczy A.F., Rowland-Jones S.L., McMichael A.J., Nixon D.F., Sullivan J.S. Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1. J. Virol. 73:1999;436.
6. Joag S.V., Anderson M.G., Clements J.E., McEntee M.F., Sharma D.P., Adams R.J., Narayan O. Antigenic variation of molecularly cloned SIVmac239 during persistent infection in a rhesus macaque. Virology. 195:1993;406.
7. Joag S.V., Li Z., Foresman L., Stephens E.B., Zhao L.J., Adany I., Pinson D.M., McClure H.M., Narayan O. Chimeric simian/human immunodeficiency virus that causes progressive loss of CD4+ T cells and AIDS in pig-tailed macaques. J. Virol. 70:1996;3189.
8. Joag S.V., Liu Z.Q., Stephens E.B., Smith M.S., Kumar A., Li Z., Wang C., Sheffer D., Jia F., Foresman L., Adany I., Lifson J., McClure H.M., Narayan O. Oral immunization of macaques with attenuated vaccine virus induces protection against vaginally transmitted AIDS. J. Virol. 72:1998;9069.
9. Johnson R.P., Glickman R.L., Yang J.Q., Kaur A., Dion J.T., Mulligan M.J., Desrosiers R.C. Induction of vigorous cytotoxic T-lymphocyte responses by live attenuated simian immunodeficiency virus. J. Virol. 71:1997;7711.
10. McMichael A.J., O'Callaghan C.A. A new look at T cells. J. Exp. Med. 187:1998;1367.
11. Meinl E., Fickenscher H., Hoch R.M., Malefyt R.D., de Waal M., Hart B.A., Wekerle H., Hohlfeld R., Fleckenstein B. Growth transformation of antigen-specific T cell lines from rhesus monkeys by Herpesvirus saimiri. Virology. 229:1997;175.
12. Nick S., Fickenscher H., Biesinger B., Born G., Jahn G., Fleckenstein B. Herpesvirus saimiri transformed human T cell lines: a permissive system for human immunodeficiency viruses. Virology. 194:1993;875.
13. Ogg G.S., Jin X., Bonhoeffer S., Dunbar P.R., Nowak M.A., Monard S., Segal J.P., Cao Y., Rowland-Jones S.L., Cerundolo V., Hurley A., Markowitz M., Ho D.D., Nixon D.F., McMichael A.J. Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA. Science. 279:1998;2103.
14. Ogg G.S., Jin X., Bonhoeffer S., Moss P., Nowak M.A., Monard S., Segal J.P., Cao Y., Rowland-Jones S.L., Hurley A., Markowitz M., Ho D.D., McMichael A.J., Nixon D.F. Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy. J. Virol. 73:1999;797.
15. Pantaleo G., Demarest J.F., Soudeyns H., Graziosi C., Denis F., Adelsberger J.W., Borrow P., Saag M.S., Shaw G.M., Sekaly R.P. Major expansion of CD8+ T cells with a predominant V beta usage during the primary immune response to HIV. Nature. 370:1994;463.
16. Reimann K.A., Li J.T., Voss G., Lekutis C., Tenner-Racz K., Racz P., Lin W., Montefiori D.C., Lee-Parritz D.E., Lu Y., Collman R.G., Sodroski J., Letvin N.L. An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeys. J. Virol. 70:1996;3198.
17. Reimann K.A., Li J.T., Veazey R., Halloran M., Park I.W., Karlsson G.B., Sodroski J., Letvin N.L. A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys. J. Virol. 70:1996;6922.
18. Rowland-Jones S.L., Dong T., Fowke K.R., Kimani J., Krausa P., Newell H., Blanchard T., Ariyoshi K., Oyugi J., Ngugi E., Bwayo J., MacDonald K.S., McMichael A.J., Plummer F.A. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest. 102:1998;1758.
19. Saha K., Ware R., Yellin M.J., Chess L., Lowy I. Herpesvirus saimiri-transformed human CD4+ T cells can provide polyclonal B cell help via the CD40 ligand as well as the TNF-alpha pathway and through release of lymphokines. J. Immunol. 157:1996;3876.
20. Shankar P., Fabry J., Lieberman J. A simple method to selectively expand HIV-1 specific cytotoxic T lymphocytes in vitro. Immunol. Invest. 24:1995;489.
21. Thorley-Lawson D.A., Miyashita E.M., Khan G. Epstein-Barr virus and the B cell: that's all it takes. Trends Microbiol. 4:1996;204.
22. Willey R.L., Smith D.H., Lasky L.A., Theodore T.S., Earl P.L., Moss B., Capon D.J., Martin M.A. In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity. J. Virol. 62:1988;139.