메뉴 건너뛰기




Volumn 68, Issue 2, 1999, Pages 276-282

Gene targeting for gene therapy: Prospects

Author keywords

Chimeric RNA DNA oligonucleotides; Gene therapy; Homologous (targeting) recombination; Mismatch correction systems; RecA Rad51 Rec2 like proteins

Indexed keywords

DNA; DOUBLE STRANDED DNA; HETERODUPLEX; OLIGONUCLEOTIDE; RECA PROTEIN; RECOMBINASE; SINGLE STRANDED DNA;

EID: 0032750967     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1006/mgme.1999.2910     Document Type: Article
Times cited : (20)

References (57)
  • 1
    • 0021131380 scopus 로고
    • Prospects for human gene therapy
    • Anderson W F. Prospects for human gene therapy. Science. 226:1984;401-409.
    • (1984) Science , vol.226 , pp. 401-409
    • Anderson, W.F.1
  • 2
    • 0030928619 scopus 로고    scopus 로고
    • Gene therapy: Promises, problems and prospects
    • Verma I M, Somia N. Gene therapy: promises, problems and prospects. Nature. 389:1997;239-242.
    • (1997) Nature , vol.389 , pp. 239-242
    • Verma, I.M.1    Somia, N.2
  • 4
    • 0031157684 scopus 로고    scopus 로고
    • Gene therapy for cancer
    • June
    • Blaese R M. Gene therapy for cancer. Sci Am. June:1997;91-95.
    • (1997) Sci Am , pp. 91-95
    • Blaese, R.M.1
  • 5
    • 0024328536 scopus 로고
    • Altering the genome by homologous recombination
    • Capecchi M R. Altering the genome by homologous recombination. Science. 244:1989;1288-1292.
    • (1989) Science , vol.244 , pp. 1288-1292
    • Capecchi, M.R.1
  • 6
    • 0030803659 scopus 로고    scopus 로고
    • Strand-specific mismatch repair in mammalian cells
    • Modrich P. Strand-specific mismatch repair in mammalian cells. J Biol Chem. 272:1997;24727-24730.
    • (1997) J Biol Chem , vol.272 , pp. 24727-24730
    • Modrich, P.1
  • 7
    • 0029918243 scopus 로고    scopus 로고
    • Genomic targeting and genetic conversion in cancer therapy
    • Kmiec E B. Genomic targeting and genetic conversion in cancer therapy. Semin Oncol. 23:1996;188-193.
    • (1996) Semin Oncol , vol.23 , pp. 188-193
    • Kmiec, E.B.1
  • 8
    • 0026560826 scopus 로고
    • Targeted homologous recombination in mammalian cells
    • Waldman A S. Targeted homologous recombination in mammalian cells. Crit Rev Oncol/Hematol. 12:1992;49-64.
    • (1992) Crit Rev Oncol/Hematol , vol.12 , pp. 49-64
    • Waldman, A.S.1
  • 9
    • 0345510967 scopus 로고
    • Directed modifications of genes by homologous recombination in mammalian cells
    • F. Grosveld, & G. Kollias. London: Academic Press
    • Doi S, Campbell C, Kucherlapati R. Directed modifications of genes by homologous recombination in mammalian cells. Grosveld F, Kollias G. Transgenic Animals. 1992;27-46 Academic Press, London.
    • (1992) Transgenic Animals , pp. 27-46
    • Doi, S.1    Campbell, C.2    Kucherlapati, R.3
  • 10
    • 21844484661 scopus 로고
    • Ideal gene therapy: Approaches and horizons
    • Lanzov V A. Ideal gene therapy: approaches and horizons. Mol Biol. 28:1994;321-327.
    • (1994) Mol Biol , vol.28 , pp. 321-327
    • Lanzov, V.A.1
  • 11
    • 0006279648 scopus 로고
    • Homologous recombination proteins and their potential applications in gene targeting technology
    • M. A Vega. Boca Raton: CRC Press
    • Kowalczykowski S C, Zarling D A. Homologous recombination proteins and their potential applications in gene targeting technology. Vega M A. Gene Targeting. 1995;167-210 CRC Press, Boca Raton.
    • (1995) Gene Targeting , pp. 167-210
    • Kowalczykowski, S.C.1    Zarling, D.A.2
  • 12
    • 0006515953 scopus 로고
    • Gene targeting in human gene therapy
    • M. A Vega. Boca Raton: CRC Press
    • Vega M A. Gene targeting in human gene therapy. Vega M A. Gene Targeting. 1995;211-229 CRC Press, Boca Raton.
    • (1995) Gene Targeting , pp. 211-229
    • Vega, M.A.1
  • 13
    • 0031935394 scopus 로고    scopus 로고
    • Therapeutic gene targeting
    • Yanez R J, Porter A CG. Therapeutic gene targeting. Gene Ther. 5:1998;149-159.
    • (1998) Gene Ther , vol.5 , pp. 149-159
    • Yanez, R.J.1    Porter, A.C.2
  • 15
    • 0001865832 scopus 로고    scopus 로고
    • DNA strand exchange proteins: A biochemical and physical comparison
    • Bianco P R, Trasy R B, Kowalczykowski S C. DNA strand exchange proteins: a biochemical and physical comparison. Frontiers Bio Sci. 3:1998;570-603.
    • (1998) Frontiers Bio Sci , vol.3 , pp. 570-603
    • Bianco, P.R.1    Trasy, R.B.2    Kowalczykowski, S.C.3
  • 17
    • 0028879965 scopus 로고
    • Homologous recombination and the roles of double-strand breaks
    • Shinohara A, Ogawa T. Homologous recombination and the roles of double-strand breaks. Trends Biochem Sci. 20:1995;387-391.
    • (1995) Trends Biochem Sci , vol.20 , pp. 387-391
    • Shinohara, A.1    Ogawa, T.2
  • 18
    • 0030970690 scopus 로고    scopus 로고
    • A super new twist on the initiation of meiotic recombination
    • Haber J E. A super new twist on the initiation of meiotic recombination. Cell. 89:1997;163-166.
    • (1997) Cell , vol.89 , pp. 163-166
    • Haber, J.E.1
  • 20
    • 0002895728 scopus 로고
    • Illegitimate recombination in mammalian cells
    • R. Kucherlapati, & G. R Smith. Washington: ASM Press
    • Roth D, Wilson J. Illegitimate recombination in mammalian cells. Kucherlapati R, Smith G R. Genetic Recombination. 1988;621-653 ASM Press, Washington.
    • (1988) Genetic Recombination , pp. 621-653
    • Roth, D.1    Wilson, J.2
  • 21
    • 0029899891 scopus 로고    scopus 로고
    • Genetic manipulation of genomes with rare-cutting endonucleases
    • Jasin M. Genetic manipulation of genomes with rare-cutting endonucleases. Trends Genet. 12:1996;224-228.
    • (1996) Trends Genet , vol.12 , pp. 224-228
    • Jasin, M.1
  • 22
    • 0031863007 scopus 로고    scopus 로고
    • Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells
    • Donoho G, Jasin M, Berg P. Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells. Mol Cell Biol. 18:1998;4070-4078.
    • (1998) Mol Cell Biol , vol.18 , pp. 4070-4078
    • Donoho, G.1    Jasin, M.2    Berg, P.3
  • 23
    • 0027264139 scopus 로고
    • Genomic targeting with purified Cre recombinase
    • Boubonis W, Saucer B. Genomic targeting with purified Cre recombinase. Nucleic Acids Res. 21:1993;2025-2029.
    • (1993) Nucleic Acids Res , vol.21 , pp. 2025-2029
    • Boubonis, W.1    Saucer, B.2
  • 24
    • 0027305095 scopus 로고
    • An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: Analysis of the β-globine locus control region
    • Fiering S, Kim C G, Epner E M, Groudin M. An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: analysis of the β-globine locus control region. Proc Natl Acad Sci USA. 90:1993;8469-8473.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8469-8473
    • Fiering, S.1    Kim, C.G.2    Epner, E.M.3    Groudin, M.4
  • 25
    • 0023646810 scopus 로고
    • Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
    • Thomas K R, Capecchi M R. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell. 51:1987;503-512.
    • (1987) Cell , vol.51 , pp. 503-512
    • Thomas, K.R.1    Capecchi, M.R.2
  • 26
    • 0002571634 scopus 로고
    • Homologous recombination in mitotically dividing mammalian cells
    • R. Kucherlapati, & G. R Smith. Washington: ASM Press
    • Subramani S, Seaton B L. Homologous recombination in mitotically dividing mammalian cells. Kucherlapati R, Smith G R. Genetic Recombination. 1988;549-573 ASM Press, Washington.
    • (1988) Genetic Recombination , pp. 549-573
    • Subramani, S.1    Seaton, B.L.2
  • 27
    • 0025773393 scopus 로고
    • Double-strand gap repair model in a mammalian gene targeting reaction
    • Valancius V, Smithies O. Double-strand gap repair model in a mammalian gene targeting reaction. Mol Cell Biol. 11:1991;4389-4397.
    • (1991) Mol Cell Biol , vol.11 , pp. 4389-4397
    • Valancius, V.1    Smithies, O.2
  • 28
    • 0022689021 scopus 로고    scopus 로고
    • Homologous recombination in Escherichia coli: Dependence on substrate length and homology
    • Shen P, Huang H V. Homologous recombination in Escherichia coli: dependence on substrate length and homology. Genetics. 112:1996;441-457.
    • (1996) Genetics , vol.112 , pp. 441-457
    • Shen, P.1    Huang, H.V.2
  • 29
    • 0026641616 scopus 로고
    • Functional structures of the RecA protein found by chimera analysis
    • Ogawa T, Shinohara A, Ogawa H, Tomizawa J. Functional structures of the RecA protein found by chimera analysis. J Mol Biol. 226:1992;651-660.
    • (1992) J Mol Biol , vol.226 , pp. 651-660
    • Ogawa, T.1    Shinohara, A.2    Ogawa, H.3    Tomizawa, J.4
  • 30
    • 0026770668 scopus 로고
    • High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors
    • Thomas K R, Deng C, Capecchi M R. High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors. Mol Cell Biol. 12:1992;2919-2923.
    • (1992) Mol Cell Biol , vol.12 , pp. 2919-2923
    • Thomas, K.R.1    Deng, C.2    Capecchi, M.R.3
  • 31
    • 0024469392 scopus 로고
    • The barrier to recombination between E. coli and S. typhimurium is disrupted in mismatch-repair mutants
    • Rayssiguier C, Thaler D S, Radman M. The barrier to recombination between E. coli and S. typhimurium is disrupted in mismatch-repair mutants. Nature. 342:1989;396-401.
    • (1989) Nature , vol.342 , pp. 396-401
    • Rayssiguier, C.1    Thaler, D.S.2    Radman, M.3
  • 32
    • 0031829701 scopus 로고    scopus 로고
    • A broadening view of recombinational DNA repair in bacteria
    • Cox M M. A broadening view of recombinational DNA repair in bacteria. Genes Cells. 3:1998;65-78.
    • (1998) Genes Cells , vol.3 , pp. 65-78
    • Cox, M.M.1
  • 33
    • 0030633568 scopus 로고    scopus 로고
    • RecA protein: Structure, function, and role in recombinational DNA repair
    • Roca A I, Cox M M. RecA protein: structure, function, and role in recombinational DNA repair. Prog Nucleic Acid Res Mol Biol. 56:1997;129-223.
    • (1997) Prog Nucleic Acid Res Mol Biol , vol.56 , pp. 129-223
    • Roca, A.I.1    Cox, M.M.2
  • 34
    • 0030949953 scopus 로고    scopus 로고
    • Evolutionary comparisons of RecA-like proteins across all major kingdoms of living organisms
    • Brendel V, Brocchieri L, Sandler S J, Clark A J, Karlin S. Evolutionary comparisons of RecA-like proteins across all major kingdoms of living organisms. Mol Evol. 44:1997;528-541.
    • (1997) Mol Evol , vol.44 , pp. 528-541
    • Brendel, V.1    Brocchieri, L.2    Sandler, S.J.3    Clark, A.J.4    Karlin, S.5
  • 35
    • 0031004885 scopus 로고    scopus 로고
    • A single-stranded DNA-binding protein is needed for efficient presynaptic complex formation by the Saccharomyces cerevisiae Rad51 protein
    • Sugiyama T, Zaitseva E M, Kowalczykowski S C. A single-stranded DNA-binding protein is needed for efficient presynaptic complex formation by the Saccharomyces cerevisiae Rad51 protein. J Biol Chem. 272:1997;7940-7945.
    • (1997) J Biol Chem , vol.272 , pp. 7940-7945
    • Sugiyama, T.1    Zaitseva, E.M.2    Kowalczykowski, S.C.3
  • 36
    • 0030716796 scopus 로고    scopus 로고
    • Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase
    • Xia S J, Shammas M A, Reis R JS. Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase. Mol Cell Biol. 17:1997;7151-7158.
    • (1997) Mol Cell Biol , vol.17 , pp. 7151-7158
    • Xia, S.J.1    Shammas, M.A.2    Reis, R.J.3
  • 37
    • 0032526320 scopus 로고    scopus 로고
    • Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation
    • Vispe S, Cazaux C, Lesca C, Defais M. Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation. Nucleic Acids Res. 26:1998;2859-2864.
    • (1998) Nucleic Acids Res , vol.26 , pp. 2859-2864
    • Vispe, S.1    Cazaux, C.2    Lesca, C.3    Defais, M.4
  • 38
    • 0029865488 scopus 로고    scopus 로고
    • RecA protein stimulates homologous recombination in plants
    • Reiss B, Klemm M, Kosak H, Schell J. RecA protein stimulates homologous recombination in plants. Proc Natl Acad Sci USA. 93:1996;3094-3098.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3094-3098
    • Reiss, B.1    Klemm, M.2    Kosak, H.3    Schell, J.4
  • 39
    • 0026515514 scopus 로고
    • Escherichia coli RecA protein modified with a nuclear location signal binds to chromosomes in living mammalian cells
    • Kido M, Yoneda Y, Nakanishi N, Uchida T, Okada Y. Escherichia coli RecA protein modified with a nuclear location signal binds to chromosomes in living mammalian cells. Exp Cell Res. 198:1992;107-114.
    • (1992) Exp Cell Res , vol.198 , pp. 107-114
    • Kido, M.1    Yoneda, Y.2    Nakanishi, N.3    Uchida, T.4    Okada, Y.5
  • 40
    • 0345631375 scopus 로고    scopus 로고
    • Targeting recombination in somatic mammalian cells: Stimulating effect of bacterial RecA protein
    • Scherbakova O G, Ogawa H, Lanzov V A, Filatov M V. Targeting recombination in somatic mammalian cells: stimulating effect of bacterial RecA protein. Doklady Rus Acad Sci. 1999.
    • (1999) Doklady Rus Acad Sci
    • Scherbakova, O.G.1    Ogawa, H.2    Lanzov, V.A.3    Filatov, M.V.4
  • 41
    • 0031917401 scopus 로고    scopus 로고
    • Biochemical basis of hyper-recombinogenic activity of Pseudomonas aeruginosa RecA protein in Escherichia coli cells
    • Namsaraev E A, Baitin D M, Bakhlanova I V, Alexseyev A A, Ogawa H, Lanzov V A. Biochemical basis of hyper-recombinogenic activity of Pseudomonas aeruginosa RecA protein in Escherichia coli cells. Mol Microbiol. 27:1998;727-738.
    • (1998) Mol Microbiol , vol.27 , pp. 727-738
    • Namsaraev, E.A.1    Baitin, D.M.2    Bakhlanova, I.V.3    Alexseyev, A.A.4    Ogawa, H.5    Lanzov, V.A.6
  • 42
    • 0030832230 scopus 로고    scopus 로고
    • Isolation of human and mouse genes based on homology to REC2 a recombinational repair gene from the fungus Ustilago maydis
    • Rice M C, Smith S T, Bullrich F, Havre P, Kmiec E B. Isolation of human and mouse genes based on homology to REC2 a recombinational repair gene from the fungus Ustilago maydis. Proc Natl Acad Sci USA. 94:1997;7417-7422.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 7417-7422
    • Rice, M.C.1    Smith, S.T.2    Bullrich, F.3    Havre, P.4    Kmiec, E.B.5
  • 44
    • 0030794157 scopus 로고    scopus 로고
    • Efficient gene targeting in mouse embrionic stem cells
    • Templeton N S, Roberts D D, Safer B. Efficient gene targeting in mouse embrionic stem cells. Gene Ther. 4:1997;700-709.
    • (1997) Gene Ther , vol.4 , pp. 700-709
    • Templeton, N.S.1    Roberts, D.D.2    Safer, B.3
  • 45
    • 0028867842 scopus 로고
    • Mismatch repair: Mechanisms and relationship to cancer susceptibility
    • Kolodner R D. Mismatch repair: mechanisms and relationship to cancer susceptibility. Trends Biochem Sci. 20:1995;397-401.
    • (1995) Trends Biochem Sci , vol.20 , pp. 397-401
    • Kolodner, R.D.1
  • 46
    • 0033054250 scopus 로고    scopus 로고
    • Excision repair invades the territory of mismatch repair
    • Sancar A. Excision repair invades the territory of mismatch repair. Nature Genet. 21:1999;247-249.
    • (1999) Nature Genet , vol.21 , pp. 247-249
    • Sancar, A.1
  • 47
    • 0029001182 scopus 로고
    • Excision repair in mammalian cells
    • Sancar A. Excision repair in mammalian cells. J Biol Chem. 27:1995;15915-15918.
    • (1995) J Biol Chem , vol.27 , pp. 15915-15918
    • Sancar, A.1
  • 48
    • 0033051168 scopus 로고    scopus 로고
    • Involvement of nucleotide-excision repair in msh2 pms1-independent mismatch repair
    • Fleck O, Lehmann E, Schar P, Kohli J. Involvement of nucleotide-excision repair in msh2 pms1-independent mismatch repair. Nature Genet. 21:1999;314-317.
    • (1999) Nature Genet , vol.21 , pp. 314-317
    • Fleck, O.1    Lehmann, E.2    Schar, P.3    Kohli, J.4
  • 49
    • 0029379540 scopus 로고
    • The search for DNA homology does not limit stable homologous pairing promoted by RecA protein
    • Yancey-Wrona J E, Camerini-Otero R D. The search for DNA homology does not limit stable homologous pairing promoted by RecA protein. Curr Biol. 5:1995;1149-1158.
    • (1995) Curr Biol , vol.5 , pp. 1149-1158
    • Yancey-Wrona, J.E.1    Camerini-Otero, R.D.2
  • 50
    • 0031571585 scopus 로고    scopus 로고
    • RecA protein assisted selection reveals a low fidelity of recognition of homology in a duplex DNA by an oligonucleotide
    • Malkov V A, Sastry L, Camerini-Otero R. RecA protein assisted selection reveals a low fidelity of recognition of homology in a duplex DNA by an oligonucleotide. J Mol Biol. 271:1997;168-177.
    • (1997) J Mol Biol , vol.271 , pp. 168-177
    • Malkov, V.A.1    Sastry, L.2    Camerini-Otero, R.3
  • 52
    • 0029993658 scopus 로고    scopus 로고
    • RNA facilitates RecA-mediated DNA pairing and strand transfer between molecules bearing limited regions of homology
    • Kotani H, Germann H, Andrus A, Vinayak R, Mullah B, Kmiec E B. RNA facilitates RecA-mediated DNA pairing and strand transfer between molecules bearing limited regions of homology. Mol Gen Genet. 250:1996;626-634.
    • (1996) Mol Gen Genet , vol.250 , pp. 626-634
    • Kotani, H.1    Germann, H.2    Andrus, A.3    Vinayak, R.4    Mullah, B.5    Kmiec, E.B.6
  • 53
    • 0030913556 scopus 로고    scopus 로고
    • Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide
    • Kren B T, Cole-Strauss, Kmiec E B, Steer C J. Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide. Hepatology. 25:1997;1462-1468.
    • (1997) Hepatology , vol.25 , pp. 1462-1468
    • Kren, B.T.1    Cole-Strauss2    Kmiec, E.B.3    Steer, C.J.4
  • 54
    • 0031953132 scopus 로고    scopus 로고
    • In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides
    • Kren B T, Bandyopadhyay P, Steer C J. In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides. Nature Med. 4:1998;285-290.
    • (1998) Nature Med , vol.4 , pp. 285-290
    • Kren, B.T.1    Bandyopadhyay, P.2    Steer, C.J.3
  • 56
    • 0028343501 scopus 로고
    • Homologous pairing and strand exchange promoted by the Escherichia coli
    • Hall S D, Kolodner R D. Homologous pairing and strand exchange promoted by the Escherichia coli. Proc Natl Acad Sci USA. 91:1994;3205-3209.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3205-3209
    • Hall, S.D.1    Kolodner, R.D.2
  • 57
    • 0028859088 scopus 로고
    • Evidence for conservative (two progeny) DNA double-strand break repair
    • Yokochi T, Kusano K, Kobayashi I. Evidence for conservative (two progeny) DNA double-strand break repair. Genetics. 139:1995;5-17.
    • (1995) Genetics , vol.139 , pp. 5-17
    • Yokochi, T.1    Kusano, K.2    Kobayashi, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.