Structure modelling and site-directed mutagenesis of the rat aromatic L- amino acid pyridoxal 5'-phosphate-dependent decarboxylase: A functional study

Proteins: Structure, Function and Genetics

Volumn 37, Issue 2, 1999, Pages 191-203

  Poupon, Anne ^a,b   Jebai, Fatmé ^c   Labesse, Gilles ^d   Gros, François ^e   Thibault, Jean ^f   Mornon, Jean Paul ^a   Krieger, Monique ^c  

^a UNIVERSITÉ PIERRE ET MARIE CURIE   (France)

^b CEA SACLAY   (France)

^c Centre de Recherche Interdisciplinaire en Biologie   (France)

^d CENTRE DE BIOCHIMIE STRUCTURALE   (France)

^e Academie des Sciences   (France)

^f UNIVERSITÉ PARIS EST CRÉTEIL   (France)

Author keywords

Amino transferases; Homology modelling; Hydrophobic cluster analysis; Sequence analysis; Structure comparison

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CARBOXYLYASE; ORNITHINE OXOACID AMINOTRANSFERASE; PYRIDOXAL 5 PHOSPHATE; TYROSINE PHENOL LYASE;

AMINO ACID SEQUENCE; ARTICLE; ENZYME CONFORMATION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; AROMATIC-L-AMINO-ACID DECARBOXYLASES; HYDROXYLATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PYRIDOXAL PHOSPHATE; RATS; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032744798     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(19991101)37:2<191::AID-PROT5>3.0.CO;2-4     Document Type: Article

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