An anomalous side reaction of the Lys303 mutant aromatic L-amino acid decarboxylase unravels the role of the residue in catalysis

Journal of Biochemistry

Volumn 121, Issue 3, 1997, Pages 604-611

  Nishino, Junji ^a   Hayashi, Hideyuki ^a   Ishii, Seiji ^a   Kagamiyama, Hiroyuki ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Aromatic L amino acid decarboxylase; Dopamine; L dopa; Pictet Spengler reaction; Pyridoxal 5' phosphate

Indexed keywords

AROMATIC LEVO AMINO ACID DECARBOXYLASE; DOPAMINE; LEVODOPA; LYSINE; MUTANT PROTEIN; SCHIFF BASE;

ABSORPTION SPECTROPHOTOMETRY; ABSORPTION SPECTROSCOPY; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; DECARBOXYLATION; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRUCTURE ACTIVITY RELATION;

EID: 0030983015     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021628     Document Type: Article

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