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Selective inhibition of the chymotrypsin-like activity of the 20S proteasome by 5methoxy-1-indanone dipeptide benzamides
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Lum RT, Nelson MG, Joly A, Horsma AG, Lee G, Meyer SM, Wick MM, Schow SR: Selective inhibition of the chymotrypsin-like activity of the 20S proteasome by 5methoxy-1-indanone dipeptide benzamides. Bioorg Med Chem Lett (1998) 8:209-214.
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Lynas JF, Harriott P, Healy A, McKervey MA, Walker B: Inhibitors of the chymotrypsin-like activity of proteasome based on di- and tri-peptidyl a-keto aldehydes (Glyoxals). Bioorg Med Chem Lett (1998) 8:373-378.
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Adams J, Behnke M, Chen S, Cruickshank AA, Dick LR, Grenier L, Klunder JM, Ma Y-T, Plamondon L, Stein RL: Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids. Bioorg Med Chem Lett (1998) 8:333-338.
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An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T ce responses
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André P, Groettrup M, Klenerman P, De Giuli R, Booth BL, Cerundolo V, Bonnevie M, Jotereau F, Zinkemagel RM, Lotteau V: An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T ce responses. Proc NatlAcadSci USA (1998) 95:13120-13124.
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Palombea VJ, Conner EM, Fuseler JW, Destree A, Davis JM, Laroux FS, Wolf RE, Huang J, Brand S, Eiott PJ, Lazarus DD, McCormack TA, Parent L, Stein R, Adams J, Grisham MB: Role of the proteasome and NF-x-B in streptococcal ce wa-induced polyarthritis. Proc Natl Acad Sei USA (1998) 95:15671-15676.
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Vandertugt CL, Rahbe SM, Eiott PJ, Dal Cantro MC, Mier SD: Treatment of established relapsing experimental autoimmune encephalomyelitis with the proteasome inhibitor PS-519. J Neuroimmunol (1999) in press.
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Eiott PJ, Pien CS, McCormack TA, Chapman ID, Adams J: Proteasome inhibition: A novel mechanism to combat asthma. J Aergy Clin Immunol (1999) 104:1-7.
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Campbe B, Adams J, Shin YK, Lefer AM: Cardioprotective effects of a novel proteasome inhibitor foowing ischemia and reperfusion in the isolated perfused rat heart. J Mol
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Adams J, Palombea VJ, Sausvie EA, Johnson J, Destree A, Lazarus DD, Mass J, Pien CS, Prakash S, Eiott PJ: Proteasome inhibitors: A novel class of potent and effective antitumor agents. Cancer Res (1999) 59:2615-2622.
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Prevention of brefeldin A-induced resistance to teniposide by the proteasome inhibitor MG132: Involvement of NF-icB activation in drug resistance
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Lin ZP, Boiler YC, Amer SM, Russe RL, Pacei KA, Patiemo SR, Kennedy KA: Prevention of brefeldin A-induced resistance to teniposide by the proteasome inhibitor MG132: Involvement of NF-icB activation in drug resistance. Cancer Res (1998) 58:3059-3065.
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Ortowski RZ, Eswara JR. Lafond-Walker A, Grever MR, Orlowski M, Dang CV: Tumor growth inhibition induced in a murine model of human Burkirt's lymphoma by a proteasome inhibitor. Cancer Res (1998) 58:4342-4348.
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Honda T, Yasutake K, Nihonmatsu N, Mercken M, Takahashi H, Murayama O, Murayama M, Sato K, Omori A, Tsubuki S, Saido TC, Takashima A: Dual roles of proteasome in the metabolism of presenilin 1. J Neurochem (1999) 72:255-261. • Suggests a role of the proteasome in the development of Alzheimer's disease through altered metabolism of presenilin 1.
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Honda, T.1
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