Spatial learning deficit in dopamine D1 receptor knockout mice

European Journal of Pharmacology

Volumn 383, Issue 2, 1999, Pages 95-106

  El Ghundi, Mufida ^a   Fletcher, Paul J ^b   Drago, John ^c   Sibley, David R ^d   O'Dowd, Brian F ^a,b   George, Susan R ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^c MONASH UNIVERSITY   (Australia)

^d NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

Dopamine D1 receptor deficient mouse; Locomotor activity; Morris water maze; Passive avoidance behavior; Spatial learning; Spontaneous alternation

Indexed keywords

DOPAMINE 1 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; CONDITIONING; CONTROLLED STUDY; GENOTYPE; HIPPOCAMPUS; KNOCKOUT MOUSE; LEARNING DISORDER; LOCOMOTION; MALE; MAZE TEST; MOUSE; NONHUMAN; PASSIVE AVOIDANCE; PREFRONTAL CORTEX; PRIORITY JOURNAL; REVIEW; SENSORIMOTOR FUNCTION; SPATIAL MEMORY;

EID: 0032739841     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00573-7     Document Type: Article

References (81)

1. Abel T., Nguyen P.V., Barad M., Deuel T.A., Kandel E.R., Bourtchouladze R. Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory. Cell. 88:1997;615-626.
2. 1 receptor agonist A-77636 increases cortical and hippocampal acetylcholine release in the rat. Eur. J. Pharmacol. 260:1994;85-87.
3. Annett L.E., McGregor A., Robbins T.W. The effects of ibotenic acid lesions of the nucleus accumbens on spatial learning and extinction in the rat. Behav. Brain Res. 31:1989;231-242.
4. Arnsten A.F. Catecholamine mechanisms in age related cognitive decline. Neurobiol. Aging. 14:1993;639-641.
5. 1 receptor mechanisms in the cognitive performance of young adult and aged monkeys. Psychopharmacology. 116:1994;143-151.
6. Bach M.E., Barad M., Son H., Zhuo M., Lu Y., Shih R., Mansuy I., Hawkins R.D., Kandel E.R. Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance cAMP signaling pathway. Proc. Natl. Acad. Sci. U.S.A. 96:1999;5280-5285.
7. Baulac M., Verney C., Berger B. Dopaminergic innervation of the para-hippocampal and hippocampal regions in the rat. Revue Neurologique. 142:1986;895-905.
8. Beninger R.J. The role of dopamine in locomotor activity and learning. Brain Res. Rev. 6:1983;173-196.
9. 1-like receptors and reward-related incentive learning. Neurosci. Biobehav. Rev. 22:1998;335-345.
10. Berman K.F., Weinberger D.R. The prefrontal cortex in schizophrenia and other neuropsychiatric diseases: in vivo physiological correlates of cognitive deficits. Prog. Brain Res. 85:1990;521-536.
11. Bernabeu R., Bevilaqua L., Ardenghi P., Bromberg E., Schmitz P., Bianchin M., Izquierdo I., Medina J.H. Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats. Proc. Natl. Acad. Sci. U.S.A. 94:1997;7041-7046.
12. Bliss T.V.P., Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature. 361:1993;31-39.
13. Bradley V.A., Welch J.L., Dick D.J. Visuospatial working memory in Parkinson's disease. J. Neurol., Neurosurg. Psychiatry. 52:1990;1228-1235.
14. Brozoski T.J., Brown R.M., Rosvold H.E., Goldman-Rakic P.S. Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkeys. Science. 205:1979;929-932.
15. 1 receptor agonists A77636 or SKF81297 on spatial working memory in aged monkeys. J. Pharmacol. Exp. Ther. 283:1997;183-189.
16. Day J., Fibiger H.C. Dopaminergic regulation of cortical acetylcholine release. Synapse. 4:1992;281-286.
17. Day J., Fibiger H.C. Dopaminergic regulation of septohippocampal cholinergic neurons. J. Neurochem. 63:1994;2086-2092.
18. 1 dopamine receptor abnormality in frontal cortex points to functional alteration of cortical cell membranes in Alzheimer's disease. Arch. Neurol. 47:1990;761-763.
19. Didriksen M. Effects of antipsychotics on cognitive behavior in rats using the delayed non-match to position paradigm. Eur. J. Pharmacol. 281:1995;241-250.
20. 1A dopamine receptors. Proc. Natl. Acad. Sci. U.S.A. 91:1994;12564-12568.
21. 2 dopamine receptors. Neuroscience. 1:1986;125-137.
22. 1 receptor gene expression attenuates alcohol-seeking behavior. Eur. J. Pharmacol. 353:1998;149-158.
23. 1A knockout mice. Mol. Pharmacol. 51:1997;6-11.
24. Gasbarri A., Verney C., Innocenzi R., Campana E., Pacitti C. Mesolimbic dopaminergic neurons innervating the hippocampal formation in the rat: a combined retrograde tracing and immunohistochemical study. Brain Res. 668:1994;71-79.
25. Gasbarri A., Sulli A., Innocenzi R., Pacitti C., Brioni J.D. Spatial memory impairment induced by lesion of the mesohippocampal dopaminergic system in the rat. Neuroscience. 74:1996;1037-1044.
26. Goldberg T.E., Weinberger D.R., Pliskin N.H., Berman K.F., Podd M.H. Recall memory deficit in schizophrenia. A possible manifestation of prefrontal dysfunction. Schizophr. Res. 2:1989;251-257.
27. Goldman-Rakic P.S. Cellular and circuit basis of working memory in prefrontal cortex of nonhuman primates. Prog. Brain Res. 85:1990;325-335.
28. Hagan J.J., Morris R.G.M. The cholinergic hypothesis of memory: a review of animal experiments. Snyder S., Iversen L.L., Iversen S.D. The Handbook of Psychopharmacology. 1987;237-323 Plenum, New York.
29. Hagan J.J., Alpert J.E., Morris R.G.M., Iversen S.D. The effect of central catecholamine depletion on spatial learning in rats. Behav. Brain Res. 9:1983;83-104.
30. 1 receptors: a combined receptor autoradiography and in vivo dialysis study. J. Neurosci. 15:1995;7150-7157.
31. 1 receptor ligands modulate cognitive and hippocampal acetylcholine release in memory-impaired aged rats. Neuroscience. 69:1995;1067-1074.
32. 5 receptor agonists induce a protein synthesis-dependent late potentiation in the CA1 region of the hippocampus. Proc. Natl. Acad. Sci. U.S.A. 92:1995;2446-2450.
33. Ichihara K., Nabeshima T., Kameyama T. Differential effects of pimozide and SCH 23390 on acquisition of learning in mice. Eur. J. Pharmacol. 164:1989;189-195.
34. 2 receptors. Eur. J. Pharmacol. 213:1992;243-249.
35. 2 receptors facilitates in vivo acetylcholine release in the hippocampus. Brain Res. 618:1993;341-345.
36. Izquierdo I., Medina H.J. Memory formation: the sequence of biochemical events in the hippocampus and its connection to activity in other brain structures. Neurobiol. Learn. Mem. 68:1997;285-316.
37. Izquierdo I., Medina J.H., Izquierdo L.A., Barros D.M., de Souza M.M., Mello e Souza T. Short- and long-term memory are differentially regulated by monoaminergic systems in the rat brain. Neurobiol. Learn. Mem. 69:1998;219-224.
38. Jarrard L.E. On the role of the hippocampus in learning and memory in the rat. Behav. Neural Biol. 60:1993;9-26. [Review].
39. Kelley A.E., Domesick V.B. The distribution of the projection from the hippocampal formation to the nucleus accumbens in the rat: an anterograde and retrograde horseradish peroxidase study. Neuroscience. 7:1982;615-630.
40. Kusuki T., Imahori Y., Ueda S., Inokuchi K. Dopaminergic modulation of LTP induction in the dentate gyrus of intact brain. NeuroReport. 8:1997;2037-2040.
41. Lamberty Y., Gower A.J. Age-related changes in spontaneous behavior and learning in NMRI mice from middle to old age. Physiol. Behav. 51:1990;81-88.
42. Lamberty Y., Gower A.J. Cholinergic modulation of spatial learning in mice in a Morris-type water maze. Arch. Int. Pharmacodyn. Ther. 309:1991;5-19.
43. Law-Tho D., Hirsch J.C., Crepel F. Dopamine modulation of synaptic transmission in rat prefrontal cortex: an in vivo electrophysiological study. Neurosci. Res. 21:1994;151-160.
44. Lee J.M., Ross E.R., Gower A., Paris J.M., Martensson R., Lorens S.A. Spatial learning deficit in the aged rats: neuroanatomical and neurochemical correlates. Brain Res. Bull. 33:1994;489-500.
45. 1A-deficient mutant mice. J. Neurosci. 16:1996;5870-5882.
46. 3H]SCH-23390. Neuroscience. 40:1991;657-671.
47. 1 deficient mutant mice do not express the late phase of hippocampal long-term potentiation. NeuroReport. 8:1997;3533-3535.
48. Mele A., Castellano C., Felici A., Cabib S., Caccia S., Oliverio A. Dopamine-N-methyl-D-aspartate interactions in the modulation of locomotor activity and memory consolidation in mice. Eur. J. Pharmacol. 308:1996;1-12.
49. Morris R.G.M. Development of a water-maze procedure for studying spatial learning in the rat. J. Neurosci. Methods. 11:1984;47-60.
50. Morris R.G.M., Garrud P., Rawlins J.N.P., O'Keefe J.O. Place navigation impaired in rats with hippocampal lesions. Nature. 297:1982;681-683.
51. Morris R.G.M., Anderson E., Lynch G.S., Baudry M. Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5. Nature. 319:1986;774-776.
52. Murphy B.L., Arnsten A.F.T., Goldman-Rakic P.S., Roth H.R. Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys. Proc. Natl. Acad. Sci. U.S.A. 93:1996;1325-1329.
53. O'Dowd B.F., Seeman P., George S.R. G protein-coupled receptors. Peroutka S.J. Handbook of Receptors and Channels. 1994;95-123 CRC Press, Boca Raton, FL.
54. 1 receptors in schizophrenia revealed by PET. Nature. 385:1997;634-636.
55. Olton D.S., Papas B.C. Spatial memory and hippocampal function. Neuropsychologia. 17:1979;669-682.
56. 5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippocampal synapses. J. Neurosci. 16:1996;7478-7486.
57. Packard M.G., White N.M. Memory facilitation produced by dopamine agonists: role of receptor subtypes and mnemonic requirements. Pharmacol. Biochem. Behav. 33:1989;511-518.
58. Park S., Holzman P.S. Schizophrenics show spatial working memory deficits. Arch. Gen. Psychiatry. 49:1992;975-982.
59. Riedel G., Reymann K.G. Metabotropic glutamate receptors in hippocampal long-term potentiation and learning and memory. Acta. Physiol. Scand. 157:1996;1-19.
60. Russell V., De Villiers A., Sagvolden T., Lamm M., Taljaard J. Altered dopaminergic function in the prefrontal cortex, nucleus accumbens and caudate-putamen of an animal model of attention-deficit hyperactivity disorder - the spontaneously hypertensive rats. Brain Res. 676:1995;343-351.
61. Sarter M., Bodewitz G., Stephens D.N. Attenuation of scopolamine induced impairment of spontaneous alternation behaviour by antagonist but not inverse agonist and agonist β-carbolines. Psychopharmacology. 94:1988;491-495.
62. 1 dopamine receptors in prefrontal cortex: involvement in working memory. Science. 251:1991;947-950.
63. Schafe G.E., Nadel N.V., Sullivan G.M., Harris A., LeDoux J.E. Memory consolidation for contextual and auditory fear conditioning is dependent on protein synthesis, PKA, and MAP kinase. Learn. Mem. 6:1999;97-110.
64. 1 receptor modulation of hippocampal-prefrontal cortical circuits integrating spatial memory with executive functions in the rat. J. Neurosci. 18:1998;1613-1621.
65. Simon H., Taghzouti K., Le Moal M. Deficits in spatial-memory tasks following lesions of septal dopaminergic terminals in the rat. Behav. Brain Res. 19:1986;7-16.
66. Squire L.R. Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. Psychol. Rev. 99:1992;195-231.
67. 1 agonist dihydrexidine releases acetylcholine and improves cognition in rats. Ann. N. Y. Acad. Sci. 777:1996;427-430.
68. Sutherland R.J., Kolb B., Whishaw I.Q. Spatial mapping: definitive disruption by hippocampal or medial frontal cortical damage in the rat. Neurosci. Lett. 31:1982;271-276.
69. Tan S.E., Liang K.C. Spatial learning alters hippocampal calcium/calmodulin-dependent protein kinase II activity in rats. Brain Res. 711:1996;234-240.
70. Tsien J.Z., Huerta P.T., Tonegawa S. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial learning. Cell. 87:1996;1327-1338.
71. Verma A., Moghaddam B. NMDA receptor antagonists impair prefrontal cortex function as assessed via spatial delayed alternation performance in rats: modulation by dopamine. J. Neurosci. 1:1996;373-379.
72. Wehner J.M., Sleight S., Upchurch M. Hippocampal protein kinase C activity is reduced in poor spatial learners. Brain Res. 523:1990;181-187.
73. Whishaw I.Q., Dunnett S.B. Dopamine depletion, stimulation or blockade in the rats disrupts spatial navigation and locomotion dependent upon beacon or distal cues. Behav. Brain Res. 18:1985;11-29.
74. Whishaw I.Q., Kolb B. Decortication abolishes place but not cue learning in rats. Behav. Brain Res. 11:1984;123-134.
75. 2 systems and spatial working memory in rats. Neuroscience. 89:1999;743-749.
76. 1 receptor in prefrontal cortex. Nature. 376:1995;572-575.
77. Winocur G. Conditional learning in aged rats: evidence of hippocampal and prefrontal cortex impairment. Neurobiol. Aging. 13:1992;131-135.
78. Winocur G., Moscovitch M. Hippocampal and prefrontal cortex contributions to learning and memory: Analysis of lesion and aging effects on maze learning in rats. Behav. Neurosci. 104:1990;544-551.
79. Wu Z.L., Thomas S.A., Villacres E.C., Xia Zsimmons M.L., Chavkin C., Plamiter R.D., Storm D.R. Altered behavior and long-term potentiation in type I adenylate cyclase mutant mice. Proc. Natl. Acad. Sci. U.S.A. 92:1995;220-224.
80. Yamamuro Y., Hori K., Iwano H., Nomura M. The relationship between learning performance and dopamine in the prefrontal cortex of the rat. Neurosci. Lett. 177:1994;83-86.
81. 1 dopamine receptors in the rodent prefrontal cortex impairs spatial working memory performance. J. Neurosci. 17:1997;8528-8535.