-
2
-
-
0021193304
-
Effects of chloroquine on the feeding mechanism of the intraerythrocytic human malarial parasite Plasmodium falciparum
-
Yayon A, Timberg R, Friedman S, Ginsburg H, 1984. Effects of chloroquine on the feeding mechanism of the intraerythrocytic human malarial parasite Plasmodium falciparum. J Protozool 31: 367-372.
-
(1984)
J Protozool
, vol.31
, pp. 367-372
-
-
Yayon, A.1
Timberg, R.2
Friedman, S.3
Ginsburg, H.4
-
3
-
-
0345652158
-
Identification of the acidic compartment of Plasmodium falciparum-infected human erythrocytes as the target of the antimalarial drug chloroquine
-
Yayon A, Cabantchik ZI, Ginsburg H, 1984. Identification of the acidic compartment of Plasmodium falciparum-infected human erythrocytes as the target of the antimalarial drug chloroquine. EMBO J 3: 2695-2700.
-
(1984)
EMBO J
, vol.3
, pp. 2695-2700
-
-
Yayon, A.1
Cabantchik, Z.I.2
Ginsburg, H.3
-
4
-
-
0031847073
-
Quinoline antimalarials: Mechanisms of action and resistance and prospects for new agents
-
Foley M, Tilley L, 1998. Quinoline antimalarials: mechanisms of action and resistance and prospects for new agents. Pharmacol Ther 79: 55-87.
-
(1998)
Pharmacol Ther
, vol.79
, pp. 55-87
-
-
Foley, M.1
Tilley, L.2
-
5
-
-
0021978338
-
Chloroquine uptake by Plasmodium falciparum-infected human erythrocytes during in vitro culture and its relationship to chloroquine resistance
-
Verdier F, Le Bras J, Clavier F, Hatin I, Blayo MC, 1985. Chloroquine uptake by Plasmodium falciparum-infected human erythrocytes during in vitro culture and its relationship to chloroquine resistance. Antimicrob Agents Chemother 27: 561-564.
-
(1985)
Antimicrob Agents Chemother
, vol.27
, pp. 561-564
-
-
Verdier, F.1
Le Bras, J.2
Clavier, F.3
Hatin, I.4
Blayo, M.C.5
-
6
-
-
0023666563
-
Efflux of chloroquine from Plasmodium falciparum: Mechanism of chloroquine resistance
-
Krogstad DJ, Gluzman IY, Kyle DE, Oduola AM, Martin SK, Milhous WK, Schlesinger PH, 1987. Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance. Science 238: 1283-1285.
-
(1987)
Science
, vol.238
, pp. 1283-1285
-
-
Krogstad, D.J.1
Gluzman, I.Y.2
Kyle, D.E.3
Oduola, A.M.4
Martin, S.K.5
Milhous, W.K.6
Schlesinger, P.H.7
-
7
-
-
0025099934
-
Antimalarial drugs: Is the lysosomotropic hypothesis still valid?
-
Ginsburg H, 1990. Antimalarial drugs: is the lysosomotropic hypothesis still valid? Parasitol Today 6: 334-337.
-
(1990)
Parasitol Today
, vol.6
, pp. 334-337
-
-
Ginsburg, H.1
-
8
-
-
0031037514
-
Identification of a chloroquine importer in Plasmodium falciparum
-
Sanchez CP, Wünsch S, Lanzer M, 1997. Identification of a chloroquine importer in Plasmodium falciparum. J Biol Chem 272: 2652-2658.
-
(1997)
J Biol Chem
, vol.272
, pp. 2652-2658
-
-
Sanchez, C.P.1
Wünsch, S.2
Lanzer, M.3
-
9
-
-
0024356582
-
Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum
-
Wilson CM, Serrano AE, Wasley A, Bogenschutz MP, Shankar AH, Wirth DF, 1989. Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum. Science 244: 1184-1186.
-
(1989)
Science
, vol.244
, pp. 1184-1186
-
-
Wilson, C.M.1
Serrano, A.E.2
Wasley, A.3
Bogenschutz, M.P.4
Shankar, A.H.5
Wirth, D.F.6
-
10
-
-
0024338609
-
Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum
-
Foote SJ, Thompson JK, Cowman AF, Kemp DJ, 1989. Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum. Cell 57: 921-930.
-
(1989)
Cell
, vol.57
, pp. 921-930
-
-
Foote, S.J.1
Thompson, J.K.2
Cowman, A.F.3
Kemp, D.J.4
-
11
-
-
0028607543
-
Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdr 1 gene
-
van Es HHG, Renkema H, Aerts H, Schurr E, 1994. Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdr 1 gene. Mol Biochem Parasitol 68: 209-219.
-
(1994)
Mol Biochem Parasitol
, vol.68
, pp. 209-219
-
-
Van Es, H.H.G.1
Renkema, H.2
Aerts, H.3
Schurr, E.4
-
12
-
-
0029047328
-
Functional complementation of the ste 6 gene of Saccharomyces cerevisiae with the pfmdr 1 gene of Plasmodium falciparum
-
Volkman SK, Cowman AF, Wirth DF, 1995. Functional complementation of the ste 6 gene of Saccharomyces cerevisiae with the pfmdr 1 gene of Plasmodium falciparum. Proc Natl Acad Sci USA 92: 8921-8925.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8921-8925
-
-
Volkman, S.K.1
Cowman, A.F.2
Wirth, D.F.3
-
13
-
-
0029840467
-
The pfmdr 1 gene of Plasmodium falciparum confers cellular resistance to antimalarial drugs in yeast cells
-
Ruetz S, Delling U, Brault M, Schurr E, Gros P, 1996. The pfmdr 1 gene of Plasmodium falciparum confers cellular resistance to antimalarial drugs in yeast cells. Proc Natl Acad Sci USA 93: 9942-9947.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9942-9947
-
-
Ruetz, S.1
Delling, U.2
Brault, M.3
Schurr, E.4
Gros, P.5
-
14
-
-
0031589733
-
Complex polymorphisms in an ∼ 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa
-
Su XZ, Kirkman LA, Fujioka H, Wellems TE, 1997. Complex polymorphisms in an ∼ 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa. Cell 91: 593-603.
-
(1997)
Cell
, vol.91
, pp. 593-603
-
-
Su, X.Z.1
Kirkman, L.A.2
Fujioka, H.3
Wellems, T.E.4
-
17
-
-
0031724298
-
Molecular epidemiology of malaria in Yaounde, Cameroon. III. Analysis of chloroquine resistance and point mutations in the multidrug resistance 1 (pfmdr 1) gene of Plasmodium falciparum
-
Basco LK, Ringwald P, 1998. Molecular epidemiology of malaria in Yaounde, Cameroon. III. Analysis of chloroquine resistance and point mutations in the multidrug resistance 1 (pfmdr 1) gene of Plasmodium falciparum. Am J Trop Med Hyg 59: 577-581.
-
(1998)
Am J Trop Med Hyg
, vol.59
, pp. 577-581
-
-
Basco, L.K.1
Ringwald, P.2
-
18
-
-
0030069741
-
Randomised trial of pyronaridine versus chloroquine for acute uncomplicated falciparum malaria in Africa
-
Ringwald P, Bickii J, Basco L, 1996. Randomised trial of pyronaridine versus chloroquine for acute uncomplicated falciparum malaria in Africa. Lancet 347: 24-28.
-
(1996)
Lancet
, vol.347
, pp. 24-28
-
-
Ringwald, P.1
Bickii, J.2
Basco, L.3
-
19
-
-
0031893366
-
Efficacy of oral pyronaridine for the treatment of acute uncomplicated falciparum malaria in African children
-
Ringwald P, Bickii J, Basco LK, 1998. Efficacy of oral pyronaridine for the treatment of acute uncomplicated falciparum malaria in African children. Clin Infect Dis 26: 946-953.
-
(1998)
Clin Infect Dis
, vol.26
, pp. 946-953
-
-
Ringwald, P.1
Bickii, J.2
Basco, L.K.3
-
20
-
-
0024328271
-
Adaptations of the Saker-Solomons test: Simple, reliable colorimetric field assays for chloroquine and its metabolites in urine
-
Mount DL, Nahlen BL, Patchen LC, Churchill FC, 1989. Adaptations of the Saker-Solomons test: simple, reliable colorimetric field assays for chloroquine and its metabolites in urine. Bull World Health Organ 67: 295-300.
-
(1989)
Bull World Health Organ
, vol.67
, pp. 295-300
-
-
Mount, D.L.1
Nahlen, B.L.2
Patchen, L.C.3
Churchill, F.C.4
-
22
-
-
0017311840
-
Human malaria parasites in continuous culture
-
Trager W, Jensen JB, 1976. Human malaria parasites in continuous culture. Science 193: 673-675.
-
(1976)
Science
, vol.193
, pp. 673-675
-
-
Trager, W.1
Jensen, J.B.2
-
23
-
-
0004265596
-
-
New York: John Wiley & Sons, Inc.
-
Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K, 1995. Short Protocols in Molecular Biology. Third edition. New York: John Wiley & Sons, Inc.
-
(1995)
Short Protocols in Molecular Biology. Third Edition
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.G.5
Smith, J.A.6
Struhl, K.7
-
24
-
-
0018606732
-
Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique
-
Desjardins RE, Canfield CJ, Haynes JD, Chulay JD, 1979. Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique. Antimicrob Agents Chemother 16: 710-718.
-
(1979)
Antimicrob Agents Chemother
, vol.16
, pp. 710-718
-
-
Desjardins, R.E.1
Canfield, C.J.2
Haynes, J.D.3
Chulay, J.D.4
-
25
-
-
0029762423
-
In vitro activity of antimalarials against clinical isolates of Plasmodium falciparum in Yaounde, Cameroon
-
Ringwald P, Bickii J, Basco LK, 1996. In vitro activity of antimalarials against clinical isolates of Plasmodium falciparum in Yaounde, Cameroon. Am J Trop Med Hyg 55: 254-258.
-
(1996)
Am J Trop Med Hyg
, vol.55
, pp. 254-258
-
-
Ringwald, P.1
Bickii, J.2
Basco, L.K.3
-
26
-
-
0031984294
-
Assessment of three in vitro tests and an in vivo test for chloroquine resistance in Plasmodium falciparum clinical isolates
-
Bickii J, Basco LK, Ringwald P, 1998. Assessment of three in vitro tests and an in vivo test for chloroquine resistance in Plasmodium falciparum clinical isolates. J Clin Microbiol 36: 243-247.
-
(1998)
J Clin Microbiol
, vol.36
, pp. 243-247
-
-
Bickii, J.1
Basco, L.K.2
Ringwald, P.3
-
27
-
-
0033044194
-
Comparison of in vivo and in vitro tests of resistance in patients treated with chloroquine in Yaounde, Cameroon
-
Ringwald P, Basco LK, 1999. Comparison of in vivo and in vitro tests of resistance in patients treated with chloroquine in Yaounde, Cameroon. Bull World Health Organ 77: 34-43.
-
(1999)
Bull World Health Organ
, vol.77
, pp. 34-43
-
-
Ringwald, P.1
Basco, L.K.2
-
29
-
-
0026674146
-
Proposals for a new therapeutic strategy for simple Plasmodium falciparum malaria attacks in Cameroon
-
Louis JP, Hengy C, Louis FJ, Gazin P, Jambou R, Gardon J, Fadat G, Trebucq A, 1992. Proposals for a new therapeutic strategy for simple Plasmodium falciparum malaria attacks in Cameroon. Trop Med Parasitol 43: 118-120.
-
(1992)
Trop Med Parasitol
, vol.43
, pp. 118-120
-
-
Louis, J.P.1
Hengy, C.2
Louis, F.J.3
Gazin, P.4
Jambou, R.5
Gardon, J.6
Fadat, G.7
Trebucq, A.8
-
30
-
-
0031711884
-
In vitro activity of lumefantrine (benflumetol) against clinical isolates of Plasmodium falciparum in Yaounde, Cameroon
-
Basco LK, Bickii J, Ringwald P, 1998. In vitro activity of lumefantrine (benflumetol) against clinical isolates of Plasmodium falciparum in Yaounde, Cameroon. Antimicrob Agents Chemother 42: 2347-2351.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 2347-2351
-
-
Basco, L.K.1
Bickii, J.2
Ringwald, P.3
-
31
-
-
0032777790
-
In vitro activity of dihydroartemisinin against clinical isolates of Plasmodium falciparum in Yaounde, Cameroon
-
Ringwald P, Bickii J, Basco LK, 1999. In vitro activity of dihydroartemisinin against clinical isolates of Plasmodium falciparum in Yaounde, Cameroon. Am J Trop Med Hyg 61: 187-192.
-
(1999)
Am J Trop Med Hyg
, vol.61
, pp. 187-192
-
-
Ringwald, P.1
Bickii, J.2
Basco, L.K.3
-
33
-
-
0024584012
-
Characterization of the dihydrofolate reductase-thymidylate synthetase gene from human malaria parasites highly resistant to pyrimethamine
-
Snewin VA, England SM, Sims PFG, Hyde JE, 1989. Characterization of the dihydrofolate reductase-thymidylate synthetase gene from human malaria parasites highly resistant to pyrimethamine. Gene 76: 41-52.
-
(1989)
Gene
, vol.76
, pp. 41-52
-
-
Snewin, V.A.1
England, S.M.2
Sims, P.F.G.3
Hyde, J.E.4
-
34
-
-
0025263958
-
Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance
-
Foote SJ, Galatas D, Cowman AF, 1990. Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance. Proc Natl Acad Sci USA 87: 3014-3017.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 3014-3017
-
-
Foote, S.J.1
Galatas, D.2
Cowman, A.F.3
-
35
-
-
0025252334
-
Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria
-
Peterson DS, Milhous WK, Wellems TE, 1990. Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria. Proc Natl Acad Sci USA 87: 3018-3022.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 3018-3022
-
-
Peterson, D.S.1
Milhous, W.K.2
Wellems, T.E.3
-
36
-
-
0028021624
-
Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine
-
Brooks DR, Wang P, Read M, Watkins WM, Sims PFG, Hyde JE, 1994. Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine. Eur J Biochem 2: 397-405.
-
(1994)
Eur J Biochem
, vol.2
, pp. 397-405
-
-
Brooks, D.R.1
Wang, P.2
Read, M.3
Watkins, W.M.4
Sims, P.F.G.5
Hyde, J.E.6
-
37
-
-
0028291789
-
Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum
-
Triglia T, Cowman AF, 1994. Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum. Proc Natl Acad Sci USA 91: 7149-7153.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7149-7153
-
-
Triglia, T.1
Cowman, A.F.2
-
38
-
-
0031924182
-
Molecular epidemiology of malaria in Yaounde, Cameroon. I. Analysis of point mutations in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum
-
Basco LK, Ringwald P, 1998. Molecular epidemiology of malaria in Yaounde, Cameroon. I. Analysis of point mutations in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum. Am J Trop Med Hyg 58: 369-373.
-
(1998)
Am J Trop Med Hyg
, vol.58
, pp. 369-373
-
-
Basco, L.K.1
Ringwald, P.2
-
39
-
-
0031900381
-
Molecular epidemiology of malaria in Yaounde, Cameroon. II. Baseline frequency of point mutations in the dihydropteroate synthase gene of Plasmodium falciparum
-
Basco LK, Ringwald P, 1998. Molecular epidemiology of malaria in Yaounde, Cameroon. II. Baseline frequency of point mutations in the dihydropteroate synthase gene of Plasmodium falciparum. Am J Trop Med Hyg 58: 374-377.
-
(1998)
Am J Trop Med Hyg
, vol.58
, pp. 374-377
-
-
Basco, L.K.1
Ringwald, P.2
-
40
-
-
0031807606
-
Molecular basis of in vivo resistance to sulfadoxine-pyrimethamine in African adult patients infected with Plasmodium falciparum malaria parasites
-
Basco LK, Tahar R, Ringwald P, 1998. Molecular basis of in vivo resistance to sulfadoxine-pyrimethamine in African adult patients infected with Plasmodium falciparum malaria parasites. Antimicrob Agents Chemother 42: 1811-1814.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 1811-1814
-
-
Basco, L.K.1
Tahar, R.2
Ringwald, P.3
-
41
-
-
0025269612
-
Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
-
Foote SJ, Kyle DE, Martin RK, Oduola AMJ, Forsyth K, Kemp DJ, Cowman AF, 1990. Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature 345: 255-258.
-
(1990)
Nature
, vol.345
, pp. 255-258
-
-
Foote, S.J.1
Kyle, D.E.2
Martin, R.K.3
Oduola, A.M.J.4
Forsyth, K.5
Kemp, D.J.6
Cowman, A.F.7
-
42
-
-
0029586497
-
Analysis of pfmdr 1 and drug susceptibility in fresh isolates of Plasmodium falciparum from sub-Saharan Africa
-
Basco LK, Le Bras J, Rhoades Z, Wilson CM, 1995. Analysis of pfmdr 1 and drug susceptibility in fresh isolates of Plasmodium falciparum from sub-Saharan Africa. Mol Biochem Parasitol 74: 157-166.
-
(1995)
Mol Biochem Parasitol
, vol.74
, pp. 157-166
-
-
Basco, L.K.1
Le Bras, J.2
Rhoades, Z.3
Wilson, C.M.4
-
43
-
-
0030951090
-
pfmdr I gene mutation and clinical response to chloroquine in Yaounde, Cameroon
-
Basco LK, Ringwald P, 1997. pfmdr I gene mutation and clinical response to chloroquine in Yaounde, Cameroon. Trans R Soc Trop Med Hyg 91: 210-211.
-
(1997)
Trans R Soc Trop Med Hyg
, vol.91
, pp. 210-211
-
-
Basco, L.K.1
Ringwald, P.2
|