Interpretation of biphasic dissociation kinetics for isomeric class II major histocompatibility complex-peptide complexes

Biophysical Journal

Volumn 77, Issue 5, 1999, Pages 2451-2461

  Anderson, Thomas G ^a   McConnell, Harden M ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PEPTIDE;

ARTICLE; COMPLEX FORMATION; HUMAN; KINETICS; MAJOR HISTOCOMPATIBILITY COMPLEX; MATHEMATICAL ANALYSIS; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PROTEIN INTERACTION;

EID: 0032734790     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(99)77081-5     Document Type: Article

References (50)

1. Abbas, A. K., A. H. Lichtman, and J. S. Pober. 1994. Cellular and Molecular Immunology. W. B. Saunders Company, Philadelphia.
2. Beeson, C., T. G. Anderson, C. Lee, and H. M. McConnell. 1996. Isomeric complexes of peptides with class II proteins of the major histocompatibility complex. J. Am. Chem. Soc. 118:977-980.
3. Beeson, C., and H. M. McConnell. 1994. Kinetic intermediates in the reactions between peptides and proteins of major histocompatibility class II. Proc. Natl. Acad. Sci. USA. 91:8842-8845.
4. Boniface, J. J., N. L. Allbritton, P. A. Reay, R. M. Kantor, L. Stryer, and M. M. Davis. 1993. pH affects both the mechanism and the specificity of peptide binding to a class II major histocompatibility complex molecule. Biochemistry. 32:11761-11768.
5. Boniface, J. J., D. S. Lyons, D. A. Wettstein, N. L. Allbritton, and M. M. Davis. 1996. Evidence for a conformational change in a class II major histocompatibility complex molecule occurring in the same pH range where antigen binding is enhanced. J. Exp. Med. 183:119-126.
6. Brown, J. H., T. S. Jardetzky, J. C. Gorga, L. J. Stern, R. G. Urban, J. L. Strominger, and D. C. Wiley. 1993. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 364: 33-39.
7. Dadaglio, G., C. A. Nelson, M. B. Deck, S. J. Petzold, and E. R. Unanue. 1997. Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody. Immunity. 6:727-738.
8. Davis, M. M. 1990. T cell receptor gene diversity and selection. Annu. Rev. Biochem. 59:475-496.
9. Davis, M. M., and P. J. Bjorkman. 1988. T-cell antigen receptor genes and T-cell recognition. Nature. 334:395-402.
10. de Kroon, A. I. P. M., and H. M. McConnell. 1993. Enhancement of peptide antigen presentation by a second peptide. Proc. Natl. Acad. Sci. 90:8797-8801.
11. de Kroon, A. I. P. M., and H. M. McConnell. 1994. Kinetics and specificity of peptide-MHC class II complex displacement reactions. J. Immunol. 152:609-619.
12. Denzin, L. K., and P. Cresswell. 1995. HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading. Cell. 82:155-165.
13. d. FEBS Lett. 294:244-246.
14. Dornmair, K., B. Rothenhaüsler, and H. M. McConnell. 1989. Structural intermediates in the reactions of antigenic peptides with MHC molecules. Cold Spring Harb. Symp. Quant. Biol. 54:409-416.
15. Fremont, D. H., W. A. Hendrickson, P. Marrack, and J. Kappler. 1996. Structures of an MHC class II molecule with covalently bound single peptides. Science. 272:1001-1004.
16. k in complex with a dominant epitope of lysozyme. Immunity. 8:305-317.
17. Garboczi, D. N., P. Ghosh, U. Utz, Q. R. Fan, W. E. Biddison, and D. C. Wiley. 1996. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature. 384:134-141.
18. Garcia, K. C., M. Degano, R. L. Stanfield, A. Brunmark, M. R. Jackson, P. A. Peterson, L. Teyton, and I. A. Wilson. 1996. An αβ T cell receptor structure at 2.5 Å and its orientation in the TCR-MHC complex. Science. 274:209-219.
19. Gimzewski, J. K., and C. Joachim. 1999. Nanoscale science of single molecules using local probes. Science. 283:1683-1688.
20. Jardetzky, T. 1997. Not just another Fab: the crystal structure of a TcR-MHC-peptide complex. Structure. 5:159-163.
21. Jardetzky, T. S., J. H. Brown, J. C. Gorga, L. J. Stern, R. G. Urban, J. L. Strominger, and D. C. Wiley. 1996. Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides. Proc. Natl. Acad. Sci. 93:734-738.
22. Jensen, P. E. 1992. Long-lived complexes between peptide and class II major histocompatibility complex are formed at low pH with no requirement for pH neutralization. J. Exp. Med. 176:793-798.
23. Liang, M. N., C. Beeson, K. Mason, and H. M. McConnell. 1995. Kinetics of the reactions between the invariant chain (85-99) peptide and proteins of the murine class II MHC. Int. Immunol. 7:1397-1404.
24. Liang, M. N., C. Lee, Y. Xia, and H. M. McConnell. 1996. Molecular modeling and design of invariant chain peptides with altered dissociation kinetics from class II MHC. Biochemistry. 35:14734-14742.
25. k. Proc. Natl. Acad. Sci. 91: 12463-12466.
26. Matsui, K., J. J. Boniface, P. A. Reay, H. Schild, B. F. d. S. Groth, and M. M. Davis. 1991. Low affinity interaction of peptide-MHC complexes with T cell receptors. Science. 254:1788-1791.
27. Matsui, K., J. J. Boniface, P. Steffner, P. A. Reay, and M. M. Davis. 1994. Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness. Proc. Natl. Acad. Sci. 91:12862-12866.
28. Mehta, A. D., M. Rief, J. A. Spudich, D. A. Smith, and R. M. Simmons. 1999. Single-molecule biomechanics with optical methods. Science. 283:1689-1695.
29. Moerner, W. E., and M. Orrit. 1999. Illuminating single molecules in condensed matter. Science. 283:1670-1676.
30. Moore, J. W., and R. G. Pearson. 1981. Kinetics and Mechanism. John Wiley and Sons, New York.
31. Natarajan, S. K., M. Assadi, and S. Sadegh-Nasseri. 1999. Stable peptide binding to MHC class II molecule is rapid and is determined by a receptive conformation shaped by prior association with low affinity peptides. J. Immunol. 162:4030-4036.
32. Rabinowitz, J. D., M. N. Liang, K. Tate, C. Lee, C. Beeson, and H. M. McConnell. 1997. Specific T cell recognition of kinetic isomers in the binding of peptide to class II major histocompatibility complex. Proc. Natl. Acad. Sci. 94:8702-8707.
33. Rabinowitz, J. D., M. Vrljic, P. M. Kasson, M. N. Liang, R. Busch, J. J. Boniface, M. M. Davis, and H. M. McConnell. 1998. Formation of a highly peptide-receptive state of class II MHC. Immunity. 9:699-709.
34. Runnels, H. A., J. C. Moore, and P. E. Jensen. 1996. A structural transition in class II major histocompatibility complex proteins at mildly acidic pH. J. Exp. Med. 183:127-136.
35. k. Nature. 338:274-276.
36. Sadegh-Nasseri, S., L. J. Stern, D. C. Wiley, and R. N. Germain. 1994. MHC class II function preserved by low-affinity peptide interactions preceding stable binding. Nature. 370:647-650.
37. Schmitt, L. 1999. Catalysis of peptide dissociation from class II MHC-peptide complexes. Proc. Natl. Acad. Sci. 96:6581-6586.
38. Schmitt, L., J. J. Boniface, M. M. Davis, and H. M. McConnell. 1998a. Conformational isomers of a class II MHC-peptide complex in solution. J. Mol. Biol. 286:2409-2420.
39. Schmitt, L., J. J. Boniface, M. M. Davis, and H. M. McConnell. 1998b. Kinetic isomers of a class II MHC-peptide complex. Biochemistry. 37:17371-17380.
40. d-peptide complexes reveal that high affinity can be achieved without large anchor residues. Immunity. 8:319-329.
41. Steinfeld, J. I., J. S. Francisco, and W. L. Hase. 1989. Chemical Kinetics and Dynamics. Prentice-Hall, Englewood Cliffs, NJ.
42. Tampé, R., and H. McConnell. 1991. Kinetics of antigenic peptide binding to the class II major histocompatibility molecule I-Ad. Proc. Natl. Acad. Sci. 88:4661-4665.
43. Tulp, A., D. Verwoerd, B. Dobberstein, H. L. Ploegh, and J. Pieters. 1994. Isolation and characterization of the intracellular MHC class II compartment. Nature. 369:120-126.
44. Viner, N. J., C. A. Nelson, B. Deck, and E. R. Unanue. 1996. Complexes generated by the binding of free peptides to class II MHC molecules are antigenically diverse compared with those generated by intracellular processing. J. Immunol. 156:2365-2368.
45. Weiss, S. 1999. Fluorescence spectroscopy of single biomolecules. Science. 283:1676-1683.
46. Wennman, S., L. Edman, and R. Rigler. 1997. Conformational fluctuations in single DNA molecules. Proc. Natl. Acad. Sci. USA. 94:10641-10646.
47. Witt, S. N., and H. M. McConnell. 1991. A first-order reaction controls the binding of antigenic peptides to major histocompatibility complex class II molecules. Proc. Natl. Acad. Sci. 88:8164-8168.
48. k. J. Am. Chem. Soc. 114:3506-3511.
49. Witt, S. N., and H. M. McConnell. 1993. The kinetics of peptide reactions with class II major histocompatibility complex membrane proteins. Acc. Chem. Res. 26:442-448.
50. Witt, S. N., and H. M. McConnell. 1994. Formation and dissociation of short-lived class II MHC-peptide complexes. Biochemistry. 33: 1861-1868.