Predicting oligonucleotide affinity to nucleic acid targets

RNA

Volumn 5, Issue 11, 1999, Pages 1458-1469

  Mathews, David H ^a   Burkard, Mark E ^a   Freier, Susan M ^b   Wyatt, Jacqueline R ^b   Turner, Douglas H ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

^b ISIS PHARMACEUTICALS   (United States)

Author keywords

Antisense oligonucleotides; Bimolecular RNA secondary structure; Hybridization; Primer extension; Reverse PCR; Reverse transcription; RNA secondary structure prediction

Indexed keywords

COMPLEMENTARY DNA; COMPLEMENTARY RNA; NUCLEIC ACID; OLIGONUCLEOTIDE; RNA;

ARTICLE; BINDING AFFINITY; COMPUTER PROGRAM; MATHEMATICAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; REVERSE TRANSCRIPTION; STRUCTURE ANALYSIS;

BASE SEQUENCE; BINDING SITES; CALORIMETRY; DNA, COMPLEMENTARY; GLOBINS; KINETICS; MODELS, THEORETICAL; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; OLIGORIBONUCLEOTIDES; RIBONUCLEASE H, CALF THYMUS; RNA; RNA, COMPLEMENTARY; RNA, MESSENGER; SOFTWARE; THERMODYNAMICS;

EID: 0032729689     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838299991148     Document Type: Article

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