Desensitization of cardiac β-adrenoceptor signaling with heart failure produced by myocardial infarction in the rat. Evidence for the role of Gi but not Gs or phosphorylating proteins

Journal of Molecular and Cellular Cardiology

Volumn 31, Issue 6, 1999, Pages 1185-1201

  Kompa, Andrew R ^a   Gu, Xin Hua ^b   Evans, Bronwyn A ^a   Summers, Roger J ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Contractile function; Forskolin; G proteins; Heart failure; mRNA expression; Myocardial infarction; Northern blot; Pertussis toxin; adrenoceptors

Indexed keywords

1 (3,4 DIHYDROXYPHENOXY) 3 (3,4 DIMETHOXYPHENETHYLAMINO) 2 PROPANOL; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; G PROTEIN RECEPTOR KINASE 2; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; PERTUSSIS TOXIN; RETINA S ANTIGEN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONOTROPISM; CONTROLLED STUDY; DESENSITIZATION; ENZYME SUBUNIT; HEART FAILURE; HEART INFARCTION; HEART LEFT ATRIUM; HEART LEFT VENTRICLE; HEART MUSCLE CONTRACTILITY; HEART PAPILLARY MUSCLE; HEART RIGHT ATRIUM; HEART RIGHT VENTRICLE; INOTROPISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR DENSITY; SIGNAL TRANSDUCTION;

EID: 0033153239     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1999.0951     Document Type: Article

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