Dietary glycine prevents the development of liver tumors caused by the peroxisome proliferator WY-14,643

Carcinogenesis

Volumn 20, Issue 11, 1999, Pages 2075-2081

  Rose, Michelle L ^b   Cattley, Russell C ^a   Dunn, Corrie ^a   Wong, Victoria ^a   Li, Xiang ^b   Thurman, Ronald G ^b  

^a CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE; PIRINIXIC ACID; VALINE;

AMINO ACID BLOOD LEVEL; ARTICLE; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; DIET; ENZYME ACTIVITY; FOOD INTAKE; LIVER TUMOR; MALE; NITROGEN BALANCE; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; RAT; TUMOR VOLUME;

ANIMALS; BODY WEIGHT; CELL DIVISION; DIET; GLYCINE; LIVER NEOPLASMS, EXPERIMENTAL; MALE; ORGAN SIZE; PEROXISOME PROLIFERATORS; PYRIMIDINES; RATS; RATS, INBRED F344;

EID: 0032723334     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.11.2075     Document Type: Article

References (34)

1. Reddy, J.K. and Lalwani, N.D. (1983) Carcinogenesis by hepatic peroxisome proliferators: Evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. CRC Crit. Rev. Toxicol., 12, 1-58.
2. Reddy, J.K., Azarnoff, D.L. and Hignite, C.E. (1980) Hypolidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature (London), 283, 397-398.
3. Marsman, D.S., Cattley, R.C., Conway, J.G. and Popp, J.A. (1988) Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and (4-chloro-6-(2,3-xylidino)-2-pyrimidinyl-thio) acetic acid (Wy-14,643) in rats. Cancer Res., 48, 6739-6744.
4. Cattley, R.C., Marsmann, D.S. and Popp, J.A. (1991) Age-related susceptibility to the carcinogenic effect of the peroxisome proliferator WY-14,643 in rat liver. Carcinogenesis, 12, 469-473.
5. Grasl-Kraupp, B., Huber, W., Taper, H. and Schulte-Hermann, R. (1991) Increased susceptibility of aged rats to hepatocarcinogenesis by the peroxisome proliferator nafenopin and the possible involvement of altered liver foci occurring spontaneously. Cancer Res., 51, 666-671.
6. Decker, K. (1990) Biologically active products of stimulated liver macrophages (Kupffer cells). Eur. J. Biochem., 192, 245-261.
7. Bojes, H.K., Germolec, D.R., Simeonova, P., Bruccoleri, A., Luster, M.I. and Thurman, R.G. (1997) Antibodies to tumor necrosis factor α prevent increases in cell replication in liver due to the potent peroxisome proliferator, WY-14,643. Carcinogenesis, 18, 669-674.
8. Rose, M.L., Germolec, D.R., Schoonhoven, R. and Thurman, R.G. (1997) Kupffer cells are causally responsible for the mitogenic effect of peroxisome proliferators. Carcinogenesis, 18, 1453-1456.
9. Rose, M.L., Germolec, D.R., Arteel, G.E., Schoonhoven, R. and Thurman, R.G. (1997) Dietary glycine prevents increases in hepatocyte proliferation caused by the peroxisome proliferator WY-14,643. Chem. Res. Toxicol., 10, 1198-1204.
10. Thurman, R.G., Rose, M.L. and Cattley, R.C. (1999) Dietary glycine prevents the development of liver tumors caused by the peroxisome proliferator WY-14,643. The Toxicologist, 48, 346.
11. 3H]thymidine adminstered by injection or osmotic pump. Carcinogenesis, 12, 1557-1561.
12. Inestrosa, N.C., Bronfman, M. and Leighton, F. (1979) Detection of peroxisomal fatty acyl-coenzyme A oxidase activity. Biochem. J., 182, 779-788.
13. Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193, 265-275.
14. Bergmeyer, H.U. (1988) Methods of Enzymatic Analysis. Academic Press, New York, NY.
15. Ohmori, S., Ikeda, M., Kira, S. and Ogata, M. (1977) Colorimetric determination of hippuric acid in urine and liver homogenate. Anal. Chem., 49, 1494-1496.
16. Ikejima, K., Iimuro, Y., Forman, D.T. and Thurman, R.G. (1996) A diet containing glycine improves survival in endotoxin shock in the rat. Am. J. Physiol., 271, G97-G103.
17. Marsman, D.S. and Popp. J.A. (1994) Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, WY-14,643. Carcinogenesis, 15, 111-117.
18. Thurman, R.G., Zhong, Z., Frankenberg, M.v., Stachlewitz, R.F. and Bunzendahl, H. (1997) Prevention of cyclosporin-induced nephrotoxicity with dietary glycine. Transplantation, 63, 1661-1667.
19. Carbo, N., Lopez-Soriano, F.J. and Argiles, J.M. (1994) The effects of tumour necrosis factor-alpha on circulating amino acids in the pregnant rat. Cancer Lett., 79, 27-32.
20. Reddy, J.K. and Krishnakantha, T.P. (1975) Hepatic peroxisome proliferation: Induction by two novel compounds structurally unrelated to clofibrate. Science, 200, 787-789.
21. Ikejima, K., Qu, W., Stachlewitz, R.F. and Thurman, R.G. (1997) Kupffer cells contain a glycine-gated chloride channel. Am. J. Physiol., 272, G1581-G1586.
22. Cattley, R.C., Kato, M., Popp, J.A., Teets, V.J. and Voss, K.S. (1994) Initiator-specific promotion of hepatocarcinogenesis by WY-14,643 and clofibrate. Carcinogenesis, 15, 1763-1766.
23. von Daniken, A., Lutz, W.K., Jackh, R. and Schlatter, C. (1984) Investigation of the potential for binding of di(2-ethylhexyl)phthalate (DEHP) and di(2-ethylhexyl)adipate (DEHA) to liver DNA in vivo. Toxical. Appl. Pharmacol., 73, 373-387.
24. von Daniken, A., Lutz, W.K. and Schlatter, C. (1983) Lack of covalent binding to rat liver DNA of the hypolipidemic drugs clofibrate and fenofibrate. Toxicol. Lett., 7, 310.
25. Goel, S.K., Lalwani, N.D., Fahl, W.E. and Reddy, J.K. (1985) Lack of covalent binding of peroxisome proliferators nafenopin and WY-14,643 to DNA in vivo and in vitro. Toxicol. Lett., 24, 37-43.
26. Cattley, R.C., Smith-Oliver, T., Butterworth, B.E. and Popp, J.A. (1988) Failure of the peroxisome proliferator WY-14,643 to induce unscheduled DNA synthesis in rat hepatocytes following in vivo treatment. Carcinogenesis, 9, 1179-1183.
27. Cattley, R.C., Marsman, D.S. and Popp, J.A. (1989) Failure of the peroxisome proliferator WY-14,643 to initiate growth-selectable foci in rat liver. Toxicology, 56, 1-7.
28. Folkman, J. (1982) Angiogenesis: Initiation and control. Ann. NY Acad. Sci., 401, 212-227.
29. Folkman, J. (1990) What is the evidence that tumors are angiogenesis dependent? J. Natl Cancer Inst., 82, 4-6.
30. Folkman, J., Cole, P. and Zimmerman, S. (1966) Tumor behavior in isolated perfused organs: In vitro growth and metastasis of biopsy material in rabbit thyroid and canine intestinal segment. Ann. Surg., 164, 491-502.
31. Rose, M.L., Madren, J., Bunzendahl, H. and Thurman, R.G. (1999) Dietary glycine inhibits the growth of B16 melanoma tumors in mice. Carcinogenesis, 20, 793-798.
32. Gersten, D.M. (1980) Control of growth and vascularity of B16 melanoma by syngeneic lymphocytes. Cell Biol. Int. Rep., 4, 407-414.
33. Min, H.Y., Doyle, L.V., Vitt, C.R., Zandonella, C.L., Stratton-Thomas, J.R., Shuman, M.A. and Rosenberg, S. (1996) Urokinase receptor antoagonists inhibit angiogenesis and primary tumor growth in syngeneic mice. Cancer Res., 56, 2428-2433.
34. Porto, L.C., Chevallier, M., Peyrol, S., Guerret, S. and Grimaud, J.A. (1990) Elastin in human, baboon, and mouse liver: An immunohistochemical and immunoelectron microscopic study. Anat. Rec., 228, 392-404.