Antibodies to tumor necrosis factor α prevent increases in cell replication in liver due to the potent peroxisome proliferator, WY- 14,643

Carcinogenesis

Volumn 18, Issue 4, 1997, Pages 669-674

  Bojes, Heidi K ^a   Germolec, Dori R ^c   Simeonova, Petia ^c   Bruccoleri, Alessandria ^c   Schoonhoven, Robert ^b   Luster, Michael I ^c   Thurman, Ronald G ^d  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b University of North Carolina at Chapel Hill   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTILIPEMIC AGENT; MESSENGER RNA; MITOGENIC AGENT; PEROXISOME PROLIFERATOR; PIRINIXIC ACID; PROTEIN KINASE C; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG INDUCED CANCER; IMMUNOHISTOCHEMISTRY; KUPFFER CELL; LIVER; LIVER CARCINOGENESIS; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIBODIES; CELL DIVISION; LIVER; MALE; MICROBODIES; MITOGENS; PYRIMIDINES; RATS; RATS, INBRED F344; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031417341     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/18.4.669     Document Type: Article

References (39)

1. Hawkins, J.M., Jones, W.E., Bonner, F.W. and Gibson, G.G. (1987) The effect of peroxisome proliferators on microsomal, peroxisomal and mitochondrial enzyme activities in the liver and kidney. Drug Metab. Dispos., 18, 441-515.
2. Reddy, J.K. and Lalwani, N.D. (1983) Carcinogenesis by hepatic peroxisome proliferators: evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. Crit. Rev. Toxicol., 12, 1-58.
3. Moser, G.J. and Smart, R.C. (1989) Hepatic tumor-promoting chlorinated hydrocarbons stimulate protein kinase C activity. Carcinogenesis, 10, 851-856.
4. Marsman, D.S., Cattley, R.C., Conway, J.G. and Popp, J.A. (1988) Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators Di(2-ethylhexyl)-phthalate and [4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio]-acetic acid (Wy-14,643) in rats. Cancer Res., 48, 6739-6744.
5. Eacho, P.I., Lanier, T.L. and Brodhecker, C.A. (1991) Hepatocellular DNA synthesis in rats given peroxisome proliferating agents: comparison of Wy-14,643 to clofibric acid, nafenopin and LY171883. Carcinogenesis, 12, 1557-1561.
6. Ames, B.N. and Gold, L.S. (1991) Endogenous mutagens and the causes of aging and cancer. Mutat. Res., 250, 3-16.
7. Cohen, S.M. and Ellwein, L.B. (1990) Cell proliferation in carcinogenesis. Science, 249, 1007-1011.
8. Cohen, S.M. and Ellwein, L.B. (1991) Genetic errors, cell proliferation and carcinogenesis. Cancer Res., 51, 6493-6505.
9. Marsman, D.S., Swanson-Pfeiffer, C.L. and Popp, J.A. (1993) Lack of comitogenicity by the peroxisome proliferator hepatocarcinogens WY-14,643 and clofibric acid. Toxicol. Appl. Pharmacol., 122, 1-6.
10. Decker, K. (1990) Biologically active products of stimulated liver macrophages (Kupffer cells). Eur. J. Biochem., 192, 245-261.
11. Decker, T., Lohmann-Matthes, M.L., Karck, U., Peters, T. and Decker, K. (1989) Comparative study of cytotoxicity, tumor necrosis factor, and prostaglandin release after stimulation of rat Kupffer cells, murine Kupffer cells, and murine inflammatory liver macrophages. J. Leukocyte Biol., 45, 139-146.
12. Buckely, A.R., Crowe, P.D. and Russell, D.H. (1988) Rapid activation of protein kinase C in isolated rat liver nuclei by prolactin, a known hepatic mitogen. Proc. Natl Acad. Sci. USA, 85, 8649-8653.
13. Birmelin, M. and Decker, K. (1984) Synthesis of prostanoids and cyclic nucleotides by phagocytosing rat Kupffer cells. Eur. J. Biochem., 142, 219-225.
14. Beyer, H.S. and Theologides, A. (1993) Tumor necrosis factor-α is a direct hepatocyte mitogen in the rat. Biochem. Mol. Biol. Int., 29, 1-4.
15. Bojes, H.K. and Thurman, R.G. (1996) Peroxisome proliferators activate Kupffer cells in vivo. Cancer Res., 56, 1-4.
16. Sirtori, C.R. (1985) Mechanisms of action of absorbable hypolipidemic drugs. Adv. Exp. Med. Biol., 183, 241-252.
17. Bayly, A.C., Roberts, R.A. and Dive, C. (1994) Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator nafenopin. Cell Biol., 125, 197-203.
18. Beutler, B. and Cerami, A. (1988) Cachectin (tumor necrosis factor): a macrophage hormone governing cellular metabolism and inflammatory response. Endocrine Rev., 9, 57-66.
19. Ankerman, P., Cote, P., Yang, S.Q., McClain, C., Nelsoln, S., Bagby, G.J., Deihl, A.M. and Bagby, G. (1992) Antibodies to tumor necrosis factor-α inhibit liver regeneration after partial hepatectomy. Am. J. Physiol., 263, G579-G585.
20. Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193, 265-275.
21. Kayama, F., Yoshida, T., Elwell, M.R. and Luster, M.I. (1995) Role of tumor necrosis factor-α in cadmium-induced hepatotoxicity. Toxicol. Appl. Pharmacol., 131, 224-234.
22. Hunt, J.S., Chen, H.L., Hu, X.L., Chen, T.Y. and Morrison, D.C. (1992) Tumor necrosis factor-α gene expression in the tissue of normal mice. Cytokine, 4, 340-346.
23. Luster, M.I., Germolec, D.R., Yoshida, T., Kayama, F. and Thompson, M. (1994) Endotoxin-induced cytokine gene expression and excretion in the liver. Hepatology, 19, 480-488.
24. Ruff, M.R. and Gifford, G.E. (1980) Purification and physico-chemical characterization of rabbit tumor necrosis factor. J. Immunol., 125, 1671-1677.
25. Cornell, R.P., Liljequist, B.L. and Bartizal, K.F. (1990) Depressed liver regeneration after partial hepatectomy of germ-free, athymic and lipopolysaccharide-resistant mice. Hepatology, 11, 916-922.
26. Feingold, K.R., Soued, M. and Grunfeld, C. (1988) Tumor necrosis factor stimulates DNA synthesis in the liver of intact rats. Biochem. Biophys. Res. Commun., 153, 576-582.
27. Endo, Y., Suzuki, R. and Kumagai, K. (1985) Induction of ornithine decarboxylase in liver and spleen of mice by interleukin 1-like factors produced from a macrophage line. Biochim. Biophys. Acta, 838, 343-350.
28. Shinagawa, T., Yoshioka, K., Kakumu, S., Wakita, T., Ishikawa, T., Itoh, Y. and Takayanagi, M. (1991) Apoptosis in cultured rat hepatocytes: the effects of tumor necrosis factor a and interferin γ. J. Pathol., 165, 247-253.
29. Tartaglia, L.A., Weber, R.F., Figari, I.S., Reynolds, C., Palladino, M.A., Jr and Goeddel, D.V. (1991) The two different receptors for tumor necrosis factor mediate distinct cellular responses. Proc. Natl Acad. Sci. USA, 88, 9292-9296.
30. Stewart, A.G., Tomlinson, P.R., Fernandes, D.J., Wilson, J.W. and Harris, T. (1995) Tumor necrosis factor alpha modulates mitogenic responses of human cultured airway smooth muscle. Am. J. Resp. Cell Molec. Biol., 12, 110-119.
31. Rumsby, R.C., Davies, M.J., Price, R.J. and Lake, B.G. (1994) Effect of some peroxisome proliferators on transforming growth factor-β gene expression and insulin-like growth factor II/mannose-6-phosphate receptor gene expression in rat liver. Carcinogenesis, 15, 419-421.
32. Rose, M.L. and Thurman, R.G. (1995) Rapid phagocytosis of particles of the peroxisome proliferator LY171883 activates Kupffer cells. Fund. Appl. Toxicol., 30, 1060 (Abstr.).
33. Michalopoulos, G.K. (1990) Liver regeneration: molecular mechanisms of growth control. FASEB J., 4, 176-187.
34. Heller, R.A. and Kranke, M. (1994) Tumor necrosis factor receptor-mediated signaling pathways. J. Cell Biol., 126, 5-9.
35. Brenner, D.A., O'Hara, M., Angel, P., Chojkier, M. and Karin, M. (1989) Prolonged activation of jun and collagenase genes by tumor necrosis factor-α. Nature (Lond.), 337, 661-663.
36. Remmer, H., Schenkman, J., Estabrook, R.W., Sasame, H., Gillette, J., Narashimhulu, S., Cooper, D.Y. and Rosenthal, O. (1996) Drug interaction with hepatic microsomal cytochrome. Mol. Pharmacol., 2, 187-190.
37. Gearing, A.J.H., Becket, P., Christodoulou, M. et al. (1994) Processing of tumor necrosis factor-α precursor by metalloproteinases. Nature, 370, 555-558.
38. McGeeham, G.M., Becherer, J.D., Bast, R.C. et al. (1994) Regulation of tumor necrosis factor-α processing by metalloproteinase inhibitor. Nature, 370, 558-561.
39. Cowper, K.B., Currin, R.T., Dawson, T.L., Lindert, K.A., Lemaster, J.J. and Thurman, R.G. (1990) A new method to monitor Kupffer cell function continuously in the perfused rat liver. Biochem. J., 266, 141-147.