Resistance of three immortalized human hepatocyte cell lines to acetaminophen and N-acetyl-p-benzoquinoneimine toxicity

Journal of Hepatology

Volumn 31, Issue 5, 1999, Pages 841-851

  McCloskey, Paschal ^a   Edwards, Robert J ^a   Tootle, Rosemary ^a   Selden, Clare ^a   Roberts, Eve ^c   Hodgson, Humphrey J F ^b  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c NONE

Author keywords

Acetaminophen; Glutathione; N acetyl p benzoquinoneimine; Toxicity

Indexed keywords

ALBUMIN; CYTOCHROME P450 ISOENZYME; DRUG METABOLITE; ETHOXYRESORUFIN DEETHYLASE; GLUTATHIONE; N ACETYL 1,4 BENZOQUINONE IMINE; PARACETAMOL;

ANIMAL CELL; ARTICLE; ARTIFICIAL LIVER; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA CONTENT; DRUG DEGRADATION; ENZYME ACTIVITY; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; LIVER CELL; LIVER MITOCHONDRION; LIVER TOXICITY; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT;

EID: 0032717171     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(99)80285-2     Document Type: Article

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