The role of potassium channels in antihistamine analgesia

Neuropharmacology

Volumn 38, Issue 12, 1999, Pages 1893-1901

  Galeotti, Nicoletta ^a   Ghelardini, Carla ^a   Bartolini, Alessandro ^a  

^a Viale GB Morgagni 65 I 50134 ^*  (Italy)

Author keywords

Antinociception; Ca2+ gated K+ channel; H1 antihistamines; K+ channel; KATP channel; mKv1.1; Pertussis toxin

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; APAMIN; CALCIUM ION; DIPHENHYDRAMINE; GLIQUIDONE; HISTAMINE H1 RECEPTOR ANTAGONIST; MEPYRAMINE; MINOXIDIL; PERTUSSIS TOXIN; PINACIDIL; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL STIMULATING AGENT; PROMETHAZINE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG MECHANISM; DRUG POTENTIATION; HOT PLATE TEST; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOTOR COORDINATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; DIPHENHYDRAMINE; DRUG SYNERGISM; HISTAMINE H1 ANTAGONISTS; ION CHANNEL GATING; MALE; MICE; OLIGONUCLEOTIDES, ANTISENSE; PAIN MEASUREMENT; PERTUSSIS TOXIN; POTASSIUM CHANNELS; PROMETHAZINE; PYRILAMINE; VIRULENCE FACTORS, BORDETELLA;

EID: 0032711826     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(99)00068-4     Document Type: Article

References (43)

1. + channels. Science. 247:1990;852-854.
2. Aronson J.K. Potassium channels in nervous tissue. Biochem. Pharmacol. 43:1992;11-14.
3. + channels in arterial smooth muscle through protein kinase C. J. Gen. Physiol. 108:1996;315-323.
4. Campos V.M., Solis E.L. The analgesic and hypothermic effects of nefopam, morphine, aspirin, diphenhydramine and placebo. J. Clin. Pharmacol. 20:1980;42-49.
5. Chandy K.G., Williams C.B., Spencer R.H., Aguilar B.A., Ghanshani S., Tempel B.L., Gutman G.A. A family of three mouse potassium channel genes with intronless coding regiones. Science. 247:1990;973-975.
6. Cook N.S., Quast U. Potassium channel pharmacology. Cook N.S. Potassium Channels: Structure, Classification, Function and Therapeutic Potential. 1990;181-255 Ellis Horwood, Chichester.
7. Cook N.S. The pharmacology of potassium channels and their therapeutic potential. Trend Pharmacol. Sci. 9:1988;21-28.
8. Edwards G., Weston A.H. The pharmacology of ATP-sensitive potassium channels. Annu. Rev. Pharmacol. Toxicol. 33:1993;597-637.
9. Galeotti N., Ghelardini C., Bartolini A. Effect of pertussis toxin on morphine, diphenhydramine, baclofen, clomipramine and physostigmine antinociception. Eur. J. Pharmacol. 308:1996;125-133.
10. Galeotti N., Ghelardini C., Papucci L., Quattrone A., Capaccioli S., Bartolini A. An antisense oligonucleotide to the mouse Shaker-like potassium channel Kv1.1 gene prevents the antinociception induced by morphine and baclofen. J. Pharmacol. Exp. Ther. 281:1997;941-949.
11. Galeotti N., Ghelardini C., Capaccioli S., Quattrone A., Bartolini A. Blockade of clomipramine and amitriptyline analgesia by an antisense oligonucleotide to mKv1.1, a mouse Shaker-like potassium channel. Eur. J. Pharmacol. 330:1997;15-25.
12. Ghelardini C., Galeotti N., Pecori Vettori A., Capaccioli S., Quattrone A., Bartolini A. Effect of potassium channels modulation on mouse feeding behaviour. Eur. J. Pharmacol. 329:1997;1-8.
13. Ghelardini C., Galeotti N., Bartolini A. Potassium channel modulators influence cognitive processes in mice. Br. J. Pharmacol. 123:1998;1079-1084.
14. Haas H.L., Konnerth A. Histamine and noradrenaline decrease calcium-activated potassium conductance in hippocampal pyramidal cells. Nature. 302:1983;432-434.
15. Haley T.J., McCormick W.G. Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse. Br. J. Pharmacol. Chemother. 12:1957;12-15.
16. + channels in the central nervous system. Cook N.S. Potassium Channels: Structure, Classification, Function and Therapeutic Potential. 1990;348-381 Ellis Horwood, Chichester.
17. Hille B. Modulation of ion-channel function by G-protein-coupled receptors. Trends Neurosci. 17:1994;531-536.
18. Holz G.G., Rane S.G., Dunlap K. GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channels. Nature. 319:1986;670-672.
19. Hopkins W.F., Tempel B.L. Members of a mouse subfamily of genes encoding voltage-gated potassium channel subunits form heteromultimers when coexpressed in Xenopus oocytes. Soc. Neurosci. Abstr. 18:1992;1093.
20. Hupert C., Yacoub M., Turgeon L.R. Effect of hydroxyzine on morphine analgesia for the treatment of postoperative pain. Anesth. Analg. 59:1980;690-696.
21. AHP, to excite ferret vagal afferents. J. Physiol. 503:1997;533-546.
22. Kuribara H., Higuchi Y., Takadoro S. Effects of central depressants on rota-rod and traction performances in mice. Jpn J. Pharmacol. 27:1977;117-126.
23. Longman S.D., Hamilton T.C. Potassium channel activator drugs: mechanism of action, pharmacological properties, and therapeutic potential. Med. Res. Rev. 12:1992;73-148.
24. Mc Cormick D.A., Williamson A. Modulation of neuronal firing in cat and guinea pig LGNd by histamine: possible cellular mechanisms of histaminergic control of arousal. J. Neurosci. 11:1991;3188-3199.
25. Meiri N., Ghelardini C., Tesco G., Galeotti N., Dahal D., Tomsic D., Cavallaro S., Quattrone A., Capaccioli S., Bartolini A., Alkon D.L. Antisense inhibition of the rodent Shaker-like potassium channel Kv1.1: disruption of memory without effects on LTP. Proc. Natl. Acad. Sci. USA. 94:1997;4430-4434.
26. + conductance by histamine H1 and H2 receptors in neurones dissociated from rat neostriatum. J. Physiol. 480:1994;233-245.
27. Narita M., Takamori K., Kawashima N., Funada M., Kamei J., Suzuki T., Misawa M., Nagase H. Activation of central ATP-sensitive potassium channels produces the antinociception and spinal noradrenaline turnover-enhancing effect in mice. Psychopharmacology. 113:1993;11-14.
28. O'Callaghan J.P., Holtzman S.G. Quantification of the analgesic activity of narcotic antagonists by a modified hot-plate procedure. J. Pharmacol. Exp. Ther. 192:1975;497-505.
29. B and κ-opioid receptor agonists. Br. J. Pharmacol. 110:1993;1049-1054.
30. B, μ and κ opioid receptors. J. Pharmacol. Exp. Ther. 276:1996;1136-1142.
31. Raffa R.B., Martinez R.P. The glibenclamide shift of centrally-acting antinociceptive agents in mice. Brain Res. 677:1995;277-282.
32. Rudy B. Diversity and ubiquity of K channels. Neuroscience. 25:1988;729-749.
33. Rumore M.M., Schlichting D.A. Analgesic effects of antihistaminics. Life Sci. 36:1985;403-406.
34. Rumore M.M., Schlichting D.A. Clinical efficacy of antihistaminics as analgesics. Pain. 25:1986;7-22.
35. 1-receptor-antagonist drug. New Engl. J. Med. 330:1994;1663-1670.
36. Stambaugh J.E., Lane C. Analgesic efficacy and pharmacokinetic evaluation of meperidine and hydroxyzine, alone and in combination. Cancer Invest. 1:1983;111-117.
37. Sunshine A., Zighelboim I., De Castro A., Sorrentino J.V., Smith D.S., Bartizek R.D., Olson N.Z. Augmentation of acetoaminophen analgesia by the antihistamine phenyltoloxamine. J. Clin. Pharmacol. 29:1989;660-664.
38. Vergoni A.V., Scarano A., Bertolini A. Pinacidil potentiates morphine analgesia. Life Sci. 50:1992;PL135-PL138.
39. Wang H., Kunkel D.D., Schwartzkroin P.A., Tempel B.L. Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain. J. Neurosci. 14:1994;4588-4599.
40. Weinreich D. Bradykinin inhibits a slow spike afterhyperpolarization in visceral sensory neurones. Eur. J. Pharmacol. 132:1986;61-63.
41. Weinreich D., Wonderlin W.F. Inhibition of calcium-dependent spike after-hyperpolarization increases excitability of rabbit visceral sensory neurones. J. Physiol. 394:1987;415-427.
42. Welch S.P., Dunlow L.D. Antinociceptive activity of intrathecally administered potassium channel openers and opioid agonists: a common mechanism of action? J. Pharmacol. Exp. Ther. 267:1993;390-399.
43. Welch S.P., Thomas C., Patrick G.S. Modulation of cannabinoid-induced antinociception after intracerebroventricular versus intrathecal administration to mice: possible mechanisms for interaction with morphine. J. Pharmacol. Exp. Ther. 272:1995;310-321.