The use of capillary high performance liquid chromatography with electrospray mass spectrometry for the analysis of small volume blood samples from serially bled mice to determine the pharmacokinetics of early discovery compounds

Rapid Communications in Mass Spectrometry

Volumn 13, Issue 23, 1999, Pages 2366-2375

  Fraser, Ian J ^a   Dear, Gordon J ^a   Plumb, Robert ^a   L'Affineur, Matthew ^a   Fraser, Donna ^a   Skippen, Alison J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BLOOD; BLOOD VESSELS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MAMMALS; MASS SPECTROMETRY;

BLOOD SAMPLES; CAPILLARY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; ELECTROSPRAY MASS SPECTROMETRY; INTRAVENOUS ADMINISTRATION; MICE MODELS; ORAL ADMINISTRATION; PHARMACOKINETIC STUDIES; SAMPLE ANALYSIS; TANDEM MASS SPECTROMETRY; TANDEM-MASS SPECTROMETRY;

PHARMACOKINETICS;

EID: 0032710653     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0231(19991215)13:23<2366::AID-RCM800>3.0.CO;2-D     Document Type: Article

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