Proteinase inhibitors from desert locust, Schistocerca gregaria: Engineering of both P1 and P1' residues converts a potent chymotrypsin inhibitor to a potent trypsin inhibitor

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1434, Issue 1, 1999, Pages 143-150

  Malik, Zulfiquar ^a   Amir, Sumaira ^a   Pál, Gábor ^b   Buzás, Zsuzsa ^a   Várallyay, Éva ^a   Antal, József ^a   Szilágyi, Zoltán ^c   Vékey, Károly ^c   Asbóth, Bence ^a   Patthy, András ^a   Gráf, László ^a,b  

^a SZENT ISTVÁN UNIVERSITY   (Hungary)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Chymotrypsin; Insect peptide; Protein protease inhibitor; Schistocerca gregaria; Subsite specificity

Indexed keywords

CHYMOTRYPSIN; CHYMOTRYPSIN INHIBITOR; PROTEINASE INHIBITOR; TRYPSIN INHIBITOR;

AMINO ACID COMPOSITION; AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; ENZYME KINETICS; ENZYME SPECIFICITY; HEMOLYMPH; LOCUST; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; CHYMOTRYPSIN; CLUSTERIN; GLYCOPROTEINS; GRASSHOPPERS; HEMOLYMPH; INSECT PROTEINS; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; PROTEASE INHIBITORS; PROTEIN ENGINEERING; SAPOSINS; TRYPSIN INHIBITORS;

INSECTA; INVERTEBRATA; SCHISTOCERCA GREGARIA; STRAWBERRY GREEN PETAL PHYTOPLASMA;

EID: 0032709689     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(99)00167-3     Document Type: Article

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