Application of magnetic resonance techniques for imaging tumour physiology

Acta Oncologica

Volumn 38, Issue 7, 1999, Pages 845-853

  Stubbs, Marion ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOENERGY; DIAGNOSTIC IMAGING; DIAGNOSTIC VALUE; DRUG MONITORING; HUMAN; IN VIVO STUDY; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

CELL HYPOXIA; HUMANS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC;

EID: 0032709570     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/028418699432536     Document Type: Article

References (48)

1. Gatenby RA. The potential role of transformation-induced metabolic changes in tumor-host interaction. Cancer Res 1995; 55: 4151-6.
2. Gatenby RA, Gawlinski ET. A reaction-diffusion model of cancer invasion 1996. Cancer Res 1996; 56: 5745-5753.
3. Schwickert G, Walenta S, Sundfor K, Rofstad EK, Mueller-KIieser W. Correlation of high lactate levels in human cervical cancer with incidence of metastasis. Cancer Res 1995; 55: 4757-9.
4. Hockel M, Schlenger K, Aral B, Mitze M, Schaffer U, Vaupel P. Association between tumor hypoxia and maligant progression in advanced cancer of the uterine cervix. Cancer Res 1996; 56: 4509-15.
5. Denekamp J. The choice of experimental models in cancer research: the key to ultimate success or failure? NMR in Biomed 1992; 5: 234-7.
6. Griffiths JR, Stevens AN, lies RA, Gordon RE, Shaw D. 31P-NMR investigation of solid tumors in the living rat. Biosci Reps 1981; 1: 319-25.
7. Griffiths JR, Cady E, Edwards RHT, McCready VR, Wilkie DR, Wiltshaw E. 31P-NMR studies of a human tumor in situ. lancet 1983; i: 1435-1436.
8. Steen RG. Response of solid tumors to chemotherapy monitored by in vivo 31P nuclear magnetic resonance spectroscopy: a review. Cancer Res 1989; 49: 4075-85.
9. de Certaines JD, Larsen VA, Podo F, Carpinelli G, Briot O, Henricksen O. In vivo 31P MRS of experimental tumours. NMR in Biomed 1993; 6: 345-365.
10. Maxwell RM. Application of nuclear magnetic resonance for investigation of the tumour microenvironment: blood perfusion and microenvironment of human tumors. In: Molls M, Vaupel P, eds. Medical radiology: diagnostic imaging and radiation oncology. Berlin: Springer Verlag, 1998: 145-59.
11. Li C-W, Kuesel AC, Padavic-Shaller, et al. Metabolic characterization of human soft tissue sarcomas in vivo and in vitro using proton-decoupled phosphorous proton magnetic resonance spectroscopy. Cancer Res 1996; 56: 2964-2972.
12. Negendank \VG, Padavic-Shaller KA, Li C-W, et al. Metabolic characterisation of non-Hodgkin's lymphomas in vivo with the use of proton-decoupled phosphorus magnetic resonance spectroscopy. Cancer Res 1995; 55: 3286-94.
13. Ross BD, Bluml S. New aspects of brain physiology. NMR in Biomed 1996; 9: 279-96.
14. Shungu DC, Bhujwalla ZM, Wehrle JP, Glickson JD. Studies of human tumors by MRS: a review. NMR in Biomed 1992; 5: 303-24.
15. Bhujwalla ZM, Glickson JD. Detection of tumor response to radiation therapy by in vivo proton MR spectroscopy. Int J Radiât Oncol Biol Phys 1996; 36: 635-9.
16. Bansal N. 23Na MRS with a shift reagent. MR Pulse 1994; 1: 18-9.
17. Ronen SM, Volk A, Mispelter J. Comparative NMR study of a differentiated rat hepatoma and its dedifferentiated subclone cultured as spheroids and as implanted tumours. NMR in Biomed 1994; 7: 278-86.
18. Bhujwalla ZM, Shungu DC, Chatham JC, Wehrle JP, Glickson JD. Glucose metabolism in RIF tumors after reduction in blood flow: an in vivo 13C and 31P NMR study. Magn Reson Med 1994; 32: 303-9.
19. Stubbs M. Tumor pH: blood perfusion and microenvironment of human tumors. In: Molls M, Vaupel P, eds. Medical radiology: diagnostic imaging and radiation oncology. Berlin: Springer Verlag, 1998: 113-20.
20. Warburg O. The metabolism of tumors. London: Constable & Co Ltd, 1930.
21. Sostman HD, Prescott DM, Dewhirst M\V, et al. MR imaging and spectroscopy for prognostic evaluation in softtissue sarcomas. Radiology 1994; 190: 269-75.
22. Griffiths JR. Are cancer cells acidic? Br J Cancer 1991; 64: 425-7.
23. Stubbs M, Bhujwalla ZM, Tozer GM, et al. An assessment of 31P MRS as a method of measuring pH in rat tumors. NMR Biomed 1992; 5: 351-9.
24. Gillies RJ, Liu Z, Bhujwalla Z. 3IP-MRS measurements of extracellular pH of tumors using 3-aminopropyIphosphonate. Am J Physiol 1994; 267: CI95-203.
25. McCoy CL, Parkins CS, Chaplin DJ, Griffiths JR, Rodrigues LM, Stubbs M. The effect of blood flow modification on intra- and extracellular pH measured by 31P MRS in murine tumours. Br J Cancer 1995; 72: 905-11.
26. Frenzel T, Koler S, Bauer H, Niedballa U, Weinmann HJ. Noninvasive in vivo measurements using a fluorinated pH probe and fluorine-19 magnetic resonance spectroscopy. Invest Radiol 1994; 29: S220-2.
27. Ojugo A, McSheehy P, Leach M, Judson I, Griffiths JR. Measurement of tumour pH gradient using 31P and 19F NMR. Proc Int Soc Magn Reson 1996; 4: 1113.
28. van Sluis R, Bhujwalla ZM, Raghunand N, et al. Proc Int Soc Magn Reson 1998; 6: 1642.
29. Gil S, Zaderenzo P, Cruz F, Cerdan S, Ballesteros P. Imidazol-1-ylalkanoic avids as extrinsic 1H NMR probes for the determination of intracellular pH, extracellular pH and cell volume. Bioorg Med Chem 1994; 2: 303-14.
30. Stubbs M, Rodrigues L, Howe FA, et al. Metabolic consequences of a reversed pH gradient in rat tumours. Cancer Res 1994; 54: 4011-6.
31. Stubbs M, Veech RL, Griffiths JR. Tumor metabolism: the lessons of magnetic resonance spectroscopy. Adv Enzyme Regul 1995; 35: 101-15.
32. Tannock IF, Rotin D. Acid pH in tumors and its potential for therapeutic exploitation. Cancer Res 1989; 49: 4373-84.
33. Maxwell RJ, Workman PJ, Griffiths JR. Demonstration of tumour-selective retention of fluorinated nitroimidazole probes by 19F magnetic resonance spectroscopy in vivo. Int J Radiât Oncol Biol Phys 1988; 16: 925-9.
34. Aboagye EO, Maxwell RJ, Kelson AB, et al. Preclinical evaluation of the fluorinated 2-nitroimidazole N-(2-hydroxy3,3,3-trifluoropropyl)-2-(2-nitro-l-imidazolyl) acetamide (SR4554) as a probe for the measurement of tumor hypoxia. Cancer Res 1997; 57: 3314-8.
35. Dardzinski BJ, Sotak CH. Rapid tissue oxygen tension mapping using 19F inversion-recovery echo-planar imaging of perfiuoro-15-crown-5-ether. Magn Reson Med 1994; 32: 88-97.
36. Robinson SP, Howe FA, Griffiths JR. Noninvasive monitoring of carbogen-induced changes in tumor blood flow and oxygénation by functional magnetic resonance imaging. Int J Radiât Oncol Biol Phys 1995; 33: 855-9.
37. Robinson SP, Rodrigues LM, Ojugo ASE, McSheehy PMJ, Ilowe FA, Griffiths JR. The response to carbogen breathing in experimental tumour models monitored by gradient-recalled echo magnetic resonance imaging. Br J Cancer 1997; 75: 1000-6.
38. Brown JM, Giaccia AJ. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res 1998; 58: 1408-16.
39. Griffiths JR, Taylor NJ, Howe FA, et al. The response of human tumors to carbogen breathing, monitored by gradientrecalled echo magnetic resonance imaging. Int J Radiât Oncol Biol Phys 1997; 39: 697-701.
40. Schiffenbauer YS, Abramovitch R, Meir G, et al. Loss of ovarian function promotes angiogenesis in human ovarian carcinoma. Proc Natl Acad Sei 1997; 94: 13203-8.
41. Demsar F, Roberts PL, Schwickert HC, et al. MRI spatial mapping technique for microvascular permeability and tissue blood volume based on macromolecular contrast agent distribution. Magn Reson Med 1997; 37: 236-42.
42. Solaiyappan M, Artemov D, Bhujwalla ZM. Functional correlation of 3-dimensional MRI maps of tumor vascular volume and permeability with 3-dimensional histological morphology. Proc Int Soc Magn Reson 1998; 6: 56.
43. Hwang YC, Kim SG, Evelhoch JL, Seyedsadr M, Ackerman JJ. Modulation of murine radiation-induced fibrosarcoma-I tumor metabolism and blood flow in situ via glucose and mannitol administration monitored by 31P and 2H nuclear magnetic resonance spectroscopy. Cancer Res 1991; 51: 3108-31018.
44. Mattiello J, Evelhoch JL. Relative volume average murine tumor blood flow measurement via deuterium magnetic resonance spectroscopy. Magn Reson Med 1991; 8: 320-34.
45. Aboagye EO, Bhujwalla ZM, Shungu DC, Glickson JD. Detection of tumor response to chemotherapy by 1H nuclear magnetic resonance spectroscopy: effect of 5-fluoruraciI on lactate levels in radiation-induced fibrosarcoma 1 tumors. Cancer Res 1997; 58: 1063-7.
46. Glaholm J, Leach MO, Collins DJ, et al. In vivo 3IP magnetic resonance spectroscopy for monitoring treatment response in breast cancer. Lancet 1989; 1: 1326-7.
47. Rodri'gues LM, Maxwell RJ, McSheehy PJM, Pinkerton CR, Robinson SP, Stubbs M, Griffiths JR. In vivo detection of ifosfamide by 31P MRS in rat tumours: increased uptake and cytotoxicity induced by carbogen breathing in GH3 prolactinomas. Br J Cancer 1997; 75: 62-8.
48. McSheehy PJM, Robinson SP, Ojugo ACE, et al. Carbogen breathing increases 5-fluorouraciI uptake and cytotoxicity in hypoxic murine RIF-1 tumours: a magnetic resonance study in vivo. Cancer Res 1998; 58: 1185-94.