Immunolocalization of the keratinocyte growth factor in benign and neoplastic human prostate and its relation to androgen receptor

Prostate

Volumn 41, Issue 4, 1999, Pages 233-242

  Planz, Bernhard ^a   Aretz, H Thomas ^a   Wang, QiFa ^a   Tabatabaei, Shahin ^a   Kirley, Sandra D ^a   Lin, Chi Wei ^a   McDougal, W Scott ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Androgen receptor; Cancer; Keratinocyte growth factor; Prostate

Indexed keywords

ALPHA ACTIN; ANDROGEN; ANDROGEN RECEPTOR; CYTOKERATIN; KERATINOCYTE GROWTH FACTOR;

ARTICLE; AUTOCRINE EFFECT; CANCER CELL; CONTROLLED STUDY; FIBROBLAST; HORMONAL CARCINOGENESIS; HORMONAL REGULATION; HORMONE RESISTANCE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MESENCHYME CELL; PARACRINE SIGNALING; PRIORITY JOURNAL; PROSTATE; PROSTATE EPITHELIUM; PROSTATE HYPERTROPHY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETORY CELL; SMOOTH MUSCLE FIBER; WESTERN BLOTTING;

EID: 0032709468     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(19991201)41:4<233::AID-PROS3>3.0.CO;2-L     Document Type: Article

References (47)

1. Berry SJ, Coffey DS, Walsh PC, Ewing LL. The development of human benign prostatic hyperplasia with age. J Urol 1984;132: 474-479.
2. Arrighi HM, Metter EJ, Guess HA, Fozzard JL. Natural history of benign prostatic hyperplasia and risk of prostatectomy. The Baltimore Longitudinal Study of Aging. Urology [Suppl] 1991; 38:4-8.
3. Parker SL, Tong T, Bolden S, Wingo PA. Cancer statistics, 1996. CA Cancer J Clin 1996;46:5-10.
4. Koivisto P, Kolmer M, Visakorpi T, Kallioniemi OP. Androgen receptor gene and hormonal therapy failure of prostate cancer. Am J Pathol 1998;152:1-9.
5. Adler AJ, Danielsen M, Robins DM. Androgen-specific gene activation via a consensus glucocorticoid response element is determined by interaction with nonreceptor factors. Proc Natl Acad Sci USA 1991;89:11660-11663.
6. Culig Z, Hobisch A, Cronauer MV, Radmayr C, Trapman J, Hittmair A, Bartsch G, Klocker H. Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor and epidermal growth factor. Cancer Res 1994;54:5474-5478.
7. Deshmukh N, Scotson J, Dodson AR, Smith PH, Ke Y, Foster CS. Differential expression of acidic and basic fibroblast growth factors in benign prostatic hyperplasia identified by immunohistochemistry. Br J Urol 1997;80:869-874.
8. Rubin RS, Osada H, Finch PW, Taylor WG, Rudikoff S, Aaronson SA. Purification and characterization of newly identified growth factor specific for epithelial cells. Proc Natl Acad Sci USA 1989;86:802-806.
9. Aaronson SA, Bottaro DP, Miki T, Ron D, Finch PW, Fleming TP, Ahn J, Taylor WG, Rubin JS. A fibroblast growth factor family member with unusual target cell specificity. Ann NY Acad Sci 1991;638:62-77.
10. Ittman M, Mansukhani A. Expression of fibroblast growth factors (FGFs) and FGF receptors in human prostate. J Urol 1997; 157:351-356.
11. Bottaro DP, Rubin JS, Ron D, Finch PW, Florio C, Aaronson SA. Characterization of the receptor for keratinocyte growth factor. J Biol Chem 1990;265:12767-12770.
12. Finch PW, Rubin JS, Miki T, Ron D, Aaronson SA. Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science 1989;245:752-755.
13. Alarid TE, Rubin JS, Young P, Chedid M, Ron D, Aaronson SA, Cunha GR. Keratinocyte growth factor functions in epithelial induction during seminal vesicle development. Proc Natl Acad Sci USA 1994;91:1074-1078.
14. Peehl DM, Wong ST, Rubin JS. KGF and EGF differentially regulate the phenotype of prostatic epithelial cells. Growth Regul 1996;6:22-31.
15. Yan G, Fukabori Y, Nikolaropoulos S, Wang F, McKeehan WL. Heparin-binding keratinocyte growth factor is a candidate stromal to epithelial cell andromedin. Mol Endocrinol 1992;6:2123-2128.
16. Planz B, Wang Q, Kirley S, Lin C-W, McDougal WS. Androgen responsiveness of stromal cells of the human prostate: regulation of cell proliferation and keratinocyte growth factor by androgen. J Urol 1998;160:1850-1856.
17. Evans RM. The steroid and thyroid hormone receptor superfamily. Science 1988;240:889-893.
18. Sar A, Lubahn DB, French FS, Wilson EM. Immunohistochemical localization of the androgen receptor in rat and human tissues. Endocinology 1990;127:3180-3186.
19. Zhang SXD, Bentel JM, Ricciardelli C, Horsfall DJ, Haagensen DE, Marshall VR, Tilley WD. Immunolocalization of apolipoprotein D, androgen receptor and prostate specific antigen in early stage prostate cancers. J Urol 1998;159:548-554.
20. Bentel JM, Tilley WD. Androgen receptors in prostate cancer. J Endocrinol 1996;151:1-11.
21. Sadi MV, Walsh PC, Barrack ER. Immunohistochemical study of androgen receptors in metastatic prostate cancer: comparison of receptor content and response to hormonal therapy. Cancer 1991;67:3057-3064.
22. Gleason DF. Classification of prostatic carcinomas. Cancer Chemother Rep 1966;50:125-128.
23. Planz B, Kirley SD, Wang QiFa, Tabatabaei SH, Aretz T, McDougal WS. Characterization of a stromal cell model of the human benign and malignant prostate from explant culture. J Urol 1999;161:1329-1336.
24. Canatan H, Chang WY, Sugimoto Y, Shidaifat F, Kulp SK, Brueggemeier RW, Lin YC. Keratinocyte growth factor (KGF/FGF-7) has a paracrine role in canine prostate: molecular cloning of mRNA encoding canine KGF. DNA Cell Biol 1996;15:247-254.
25. Chang WY, Kulp SK, Sugimoto Y, Canatan H, Shidaifat F, Inpanbutr N, Lin YC. Detection of keratinocyte growth factor (KGF) messenger ribonucleic acid and immunolocalization of KGF in the canine testis. Endocrine 1996;5:247-255.
26. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 1976;72:248-254.
27. Taplin ME, Bubley GJ, Shuster TD, Frantz ME, Spooner AE, Ogata GK, Keer HN, Balk SP. Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer. N Engl J Med 1995;332:1393-1398.
28. Chromczynski P, Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
29. Finch PW, Cunha GR, Rubin JS, Wong J, Ron D. Pattern of keratinocyte growth factor and keratinocyte growth factor receptor expression during mouse fetal development suggests a role in mediating morphogenetic mesenchymal-epithelial interactions. Dev Dyn 1995;203:223-240.
30. McNeal JE. Normal histology of the prostate. Am J Surg Pathol 1988;12:619-633.
31. Steiner MS, Barrack ER. Transforming growth factor β1 overproduction in prostate cancer: effects of growth in vivo and in vitro. Mol Endocrinol 1992;5:15-25.
32. Cunha CR, Sugimura Y, Forster B, Rubin JS, Aaronson SA. The role of growth factors in the development and growth of the prostate and seminal vesicle. Biomed Pharmacother [Suppl] 1994;48:9-17.
33. Marton R, Isaacs J, Isaacs W. Differential effects of growth factor antagonists on neoplastic and normal prostatic cells. Prostate 1990;17:327-336.
34. McNeal JE. Pathology of benign prostatic hyperplasia: insight into etiology. Urol Clin North Am 1990;17:477-486.
35. Ruizefeld de Winter JA, Janssen PJA, Sleddens HMEB, Verleun-Mooijman MCT, Trapman J, Brinkmann AO, Santerse AB, Schroeder FH, Van der Kwaast TH. Androgen receptor status in localized and locally progressive hormone refractory human prostate cancer. Am J Path 1994;144:735-746.
36. Puy L, MacLusky NJ, Becker L, Karsan N, Trachtenberg J, Brown TJ. Immunocytochemical detection of androgen receptor in human temporal cortex: characterization and application of polyclonal androgen receptor antibodies in frozen and paraffin-embedded tissues. J Steroid Biochem 1995;55:197-209.
37. McGearvy TW, Stearns ME. Keratinocyte growth factor and receptor mRNA expression in benign and malignant human prostate. Exp Mol Pathol 1995;63:52-62.
38. Baskin LS, Sutherland RS, Thomson AA, Nguyen H-T, Morgan DM, Hayward SW, Hom YK, Disandro M, Cunha GR. Growth factors in bladder wound healing. J Urol 1997;157:2388-2395.
39. Werner S, Peters KG, Longaker MT, Fuller-Pace F, Banda MJ, Williams LT. Large induction of keratinocyte growth factor expression in the dermis during wound healing. Proc Natl Acad Sci USA 1992;89:6896-6900.
40. Finch PW, Murphy F, Cardinale I, Krueger JG. Altered expression of keratinocyte growth factor and its receptor in psoriasis. Am J Pathol 1997;151:1619-1628.
41. Bajaj-Elliott M, Breese E, Poulsom R, Fairclough PD, MacDonald TT. Keratinocyte growth factor in inflammatory bowel disease. Increased mRNA transcripts in ulcerative colitis compared with Crohn's disease in biopsies and isolated mucosal myofibroblasts. Am J Pathol 1997;151:1469-1476.
42. Koji T, Chedid M, Rubin JS, Slayden OD, Csaky KG, Aaronson SA, Brenner RM. Progesterone-dependent expression of keratinocyte growth factor mRNA in stromal cells of the primate endometrium: keratinocyte growth factor as a progestomedin. J Cell Biol 1994;125:393-401.
43. Peehl DM, Wong ST, Rubin JS. KGF and EGF differentially regulate the phenotype of prostatic epithelial cells. Growth Regul 1996;6:22-31.
44. Leung HY, Mehta P, Gray LB, Collins AT, Robson CN, Neal DE. Keratinocyte growth factor expression in hormone insensitive prostate cancer. Oncogene 1997;15:1115-1120.
45. Kimura N, Watanabe M, Kubota M, Oonuma T, Mizokami A, Nagura H. Quantitative analysis of immunohistochemical androgen receptor and Ki67 in prostatic carcinoma and its relationship to histologic grade. Oncol Rep 1994;1:69-73.
46. Miyamato KK, McSherry SA, Dent GA, Sar M, Wilson EM, French FS, Sharrief Y, Mohler JL. Immunohistochemistry of the androgen receptor in human benign and malignant prostate tissue. J Urol 1993;149:1015-1018.
47. Hobisch A, Culig Z, Radmayr C, Bartsch G, Klocker H, Hittmair A. Androgen receptor status of lymph node metastases from prostate cancer. Prostate 1996;28:129-135.