Characterization of a stromal cell model of the human benign and malignant prostate from explant culture

Journal of Urology

Volumn 161, Issue 4, 1999, Pages 1329-1336

  Planz, Bernhard ^a   Kirley, Sandra D ^a   Wang, Qifa ^a   Tabatabaei, Shahin ^a   Aretz, H Thomas ^a   Mcdougal, W Scott ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Epithelial cells; Prostate; Stromal cells

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANOLONE; FLUTAMIDE; HYDROXYFLUTAMIDE; INSULIN; SELENIUM; THYMIDINE DERIVATIVE; TRANSFERRIN;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTATE CANCER; SMOOTH MUSCLE; STROMA CELL;

EID: 0032862563     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(01)61679-3     Document Type: Article

References (41)

1. Arrighi, H. M., Metter, E. J., Guess, H. A. and Fozzard, J. L.: Natural history of benign prostatic hyperplasia and risk of prostatectomy: the Baltimore longitudinal study of aging. Urology, Suppl., 35: 4, 1991.
2. McConnell, J. D.: Benign prostatic hyperplasia. In: Campbells' Urology, 7th edition. Edited by Walsh, P. C., Retik, A. B., Vaughan, E. D. and Wein, A. J. Philadelphia: Saunders, pp. 1429-1432, 1998.
3. Parker, S. L., Tong, T., Bolden, S. and Wingo, P. A.: Cancer statistics 1996. Ca, 46: 5, 1996.
4. Ronnov-Jessen, L., Peterson, O. and Bisell, M.: Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction. Physiological Rev., 76: 69, 1996.
5. Chung, L. W. K., Gleave, M. E., Hsieh, J. T., Hong, S. J. and Zhau, H. E.: Reciprocal mesenchymal-epithelial interaction affecting prostate tumor growth and hormonal responsiveness. Cancer Surv., 11: 91, 1991.
6. Chung, L. W. K., Chang, S. and Bell, C.: Coinoculation of tumorigenetic rat prostate mesenchymal cells results in the development of carcinosarcoma in syngeneic and athymic animals. Int. J. Cancer, 43: 1179, 1989.
7. Cunha G. R., Hayward, S. W., Dahiya, R. and Foster, B. A.: Smooth muscle- epithelial interactions in normal and neoplastic prostatic development. Acta Anat., 155: 63, 1996.
8. Hayward, S. W., Cunha, G. R. and Dahiya, R.: Normal development and carcinogenesis of the prostate; a unifying hypothesis. Ann. NY Acad. Sci., 1996.
9. Chromczynski, P. and Sacchi, N.: Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162: 156, 1987.
10. Taplin, M. E., Bubley, G. J., Shuster, T. D., Frantz, M. E., Spooner, A. E., Ogata, G. K., Keer, H. N. and Balk, S. P.: Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer New Engl. J. Med., 332: 1393, 1995.
11. Svitkina, T. M., Veskhorsky A. B. and Bonisy C. G.: Improved procedures for electron microscopic visualization of the cytoskeleton of cultured cells. J. Struct. Biol., 115: 290, 1995.
12. Levine, A. C., Ren, M., Huber, G. K. and Kirschenbaum, A.: The effect of androgen, estrogen and growth factors on the proliferation of cultured fibroblasts derived from human fetal prostates. Endocrinology, 130: 2413, 1992.
13. Tsugaya, M., Habib, F. K., Chisholm, G. D., Ross, M., Tozawa, K., Hayashi, Y., Kohri, K. and Tanaka, S.: Testosterone metabolism in primary cultures of epithelial cells and stroma from benign prostatic hyperplasia. Urol. Res., 24: 265, 1996.
14. Bayne, C. W., Donelly, F., Chapman, K., Bollina, P., Buck, C. and Habib, F. K.: A novel coculture model for benign prostatic hyperplasia expressing both isoforms of 5α-reductase. J. Clin. Endocrinol. Metab., 83: 206, 1998.
15. Chang, S. M. and Chung, L. W.: Interaction between prostatic fibroblast and epithelial cells in culture: role of androgen. Endocrinology, 125: 2719, 1989.
16. Collins, A. T., Zhiming, B., Gilmore, K. and Neal, D. E.: Androgen and oestrogen responsiveness of stromal cells derived from the human hyperplastic prostate: oestrogen regulation of the androgen receptor. J Endocrinol., 143: 269, 1994.
17. Yan, G., Fukabori, Y., Nikolaropoulos, S., Wang, F. and McKeehan, W. L.: Heparin-binding keratinocyte growth factor is a candidate stromal to epithelial cell andromedin. Mol. Endocrinol., 6: 2123, 1992.
18. Sherwood, E. R., Van Dongen, J. L., Wood, C. G., Liao, S., Kozlowski, J. M. and Lee, C.: Epidermal growth factor activation in androgen-independent but not androgen-stimulated growth of human prostatic carcinoma cells. Br. J. Cancer, 77: 855, 1998.
19. Geldof, A. A., De Kleijn, M. A., Rao, B. R. and Newling, D. W.: Nerve growth factor stimulates in vitro invasive capacity of DU145 human prostatic cancer cells. J. Cancer Res. Clin. Oncol., 123: 107, 1997.
20. Okamoto, M., Lee, C. and Oyasu, R.: Interleukin-6 as a paracrine and autocrine growth factor in human prostatic carcinoma cells in vitro. Cancer Res., 57: 141, 1997.
21. Rokhlin, O. W., Griebling, T. L., Karassina, N. V., Raines, M. A. and Cohen, M. B.: Human prostate carcinoma cell lines secrete GM-CSF and express GM-CSF-receptor on their cell surface. Anticancer Res., 16: 557, 1996.
22. Tillotson, J. K. and Rose, D. P.: Endogenous secretion of epidermal growth factor peptides stimulates growth of DU145 prostate cancer cells. Cancer Lett., 60: 109, 1991.
23. Peehl, D. M. and Sellers, R. G.: Induction of smooth muscle phenotype in cultured human prostatic stromal cells. Exp. Cell Res., 232: 208, 1997.
24. Katchen, B. and Boxbaum, S.: Disposition of a new, nonsteroid antiandrogen ααα-tri-fluoro-2-methyl-4′-nitro-m-propionotoluidide (flutamide) in men following a single oral 200 mg dose. J. Clin. Endocrinol. Metab., 41: 373, 1975.
25. Wilding G., Chen, M. and Gelman, E. P.: Aberrant response in vitro of hormone-responsive prostate cancer cells to antiandrogens. Prostate, 14: 103, 1989.
26. Kemppainen, J. A. and Wilson, E. M.: Agonist and antagonist activities of hydroxyflutamide and casodex relate to androgen receptor stabilization. Urology, 48: 157, 1996.
27. Ruizefeld, J. A., Trapman, J., Vermey, M., Mulder, E., Zegers, N. D. and van der Kwast, T.: Androgen receptor expression in human tissues: an immunohistochemical study. J. Histochem. Cytochem., 39: 927, 1991.
28. Miyamato, K. K., McSherry, S. A., Dent, G. A., Sar, M., Wilson, E. M., French, F. S., Sharrief, Y. and Mohler, J. L.: Immunohistochemistry of the androgen receptor in human benign and malignant prostate tissue. J Urol., 149: 1015, 1993.
29. Cunha, C. R., Sugimura, Y., Forster, B., Rubin, J. S. and Aaronson, S. A.: The role of growth factors in the development and growth of the prostate and seminal vesicle. Biomed. Pharmacother. (Suppl. 1), 48: 9s, 1994.
30. Planz, B, Wang, Q. F., Kirley, S., Lin, C. W. and McDougal, S. W.: Androgen responsiveness of stromal cells of the human prostate: regulation of cell proliferation and keratinocyte growth factor by androgen. J. Urol., 160: 1850, 1998.
31. Alarid, T. E., Rubin, J. S., Young, P., Chedid, M., Ron, D., Aaronson, S. A. and Cunha, G. R.: Keratinocyte growth factor functions in epithelial induction during seminal vesicle developement. Proc. Natl. Acad Sci. USA, 91: 1074, 1994.
32. Sadi, M. V., Walsh, P. C. and Barrack, E. R.: Immunohistochemical study of androgen receptors in metastatic prostate cancer: comparison of receptor content and response to hormonal therapy Cancer, 67: 3057, 1993.
33. Taketa, S., Nishi, N., Takasuga, H., Okutani, T., Takenaka, I. and Wada, F.: Differences in growth requirements between epithelial and stromal cells derived from rat ventral prostate in serum-free primary culture. Prostate, 17: 207, 1990.
34. Koistra, A. Elissen, N. M. J., Koenig, J. J., Vermey, M., van der Kwast, T. H., Romijn, J. C. and Schroeder, F. H.: Immunohistochemical characterization of explant cultures of human prostatic stromal cells. Prostate, 27: 42, 1995.
35. Janin, A., Konttinen, Y. T., Groenblad, M., Karhunen, P., Gosset, D. and Malmstroem, M.: Fibroblast markers in labial salivary gland biopsies in progressive systemic sclerosis. Clin. Exp. Rheumatol., 8: 237, 1990.
36. Krill, D., Shuman, M., Thompson, T., Becich, M. J. and Strom, S. C.: A simple method for the isolation and culture of epithelial and stromal cells from benign and neoplastic prostates. Urology, 49: 981, 1997.
37. Kassen, A., Sutkowski, H. A., Sensibar, J. A., Kozlowski, J. M. and Lee, C.: Stromal cells of the human prostate: initial isolation and characterization. Prostate, 28: 89, 1996.
38. Nemeth, J. A. and Lee, C.: Prostatic ductal system in rats: regional variation in stromal organization. Prostate, 28: 124, 1996.
39. Sappino, A. P., Schurch, W. and Gabbiani, G.: Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations. Lab. Invest., 63: 144, 1990.
40. Gabbiani, G.: The biology of the myofibroblast. Kidney Int., 41: 530, 1992.
41. Ronnov-Jessen, L., van Deurs, B., Celis, J. E. and Petersen, O. W.: Smooth muscle differentiation in cultured human breast gland stromal cells. Lab. Invest, 63: 532, 1990.