Laboratory diagnosis of heparin-induced thrombocytopenia

Clinical and Applied Thrombosis/Hemostasis

Volumn 5, Issue SUPPL. 1, 1999, Pages

  Walenga, Jeanine M ^a   Jeske, Walter P ^a   Fasanella, Anthony R ^a   Wood, Jennifer J ^a   Ahmad, Sarfraz ^a   Bakhos, Mamdouh ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Assays; Heparin; Laboratory tests; Platelets; Thrombocytopenia

Indexed keywords

HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; THROMBOCYTE FACTOR 4;

CONFERENCE PAPER; DIAGNOSTIC ACCURACY; DIAGNOSTIC APPROACH ROUTE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; PRIORITY JOURNAL; SEROTONIN RELEASE; THROMBOCYTE AGGREGATION; THROMBOCYTOPENIA;

EID: 0032705897     PISSN: 10760296     EISSN: None     Source Type: Journal    
DOI: 10.1177/10760296990050s105     Document Type: Conference Paper

References (34)

1. Amiral J, Bridey F, Dreyfus M, et al. Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia. Thromb Haemost 1992;68:95.
2. Chong BH. Heparin-induced thrombocytopenia. Br J Haematol 1995;89:431.
3. Greinacher A, Pötzsch B, Amiral J. Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen. Thromb Haemost 1994;71:247.
4. Kelton JG, Sheridan DP, Santos AV, et al. Heparin-induced thrombocytopenia: laboratory studies. Blood 1988;72:925.
5. Suh JS, Malik MI, Aster RH, et al. Characterization of the humoral response in heparin-induced thrombocytopenia. Am J Hematol 1997;54:196.
6. King DJ, Kelton JG. Heparin-associated thrombocytopenia. Ann Intern Med 1984;100:535.
7. Powers PJ, Kelton JG, Carter CJ. Studies on the frequency of heparin-associated thrombocytopenia. Thromb Res 1984;33:439.
8. Walls JT, Curtis JJ, Silver D, et al. Heparin-induced thrombocytopenia in patients who undergo open heart surgery. Surgery 1990; 108:686.
9. Wallis DE, Lewis BE, Pifarré R, et al. Active surveillance for heparin-induced thrombocytopenia and thromboembolism. Chest 1994;106:1208.
10. Look KA, Sahud M, Flaherty S, et al. Heparin-induced platelet aggregation vs. platelet factor 4 enzyme-linked immunosorbent assay in the diagnosis of heparin-induced thrombocytopenia-thrombosis. Coag Transfus Med 1997;108:78.
11. Sheridan D, Carter C, Kelton JG. A diagnostic test for heparin-induced thrombocytopenia. Blood 1986;67:27.
12. Collins JL, Aster RH, Moghaddam M, et al. Diagnostic testing for heparin-induced thrombocytopenia (HIT): an enhanced platelet factor 4 complex enzyme linked immunosorbent assay (PF4 ELISA). Blood 1997;90(Suppl 1):761a.
13. Jeske WP, Szatkowski E, Hoppensteadt D, et al. Development of a flow cytometric assay for the laboratory diagnosis of heparin induced thrombocytopenia. Blood 1996;88:317a.
14. Lee DH, Warkentin TE, Denomme GA, et al. A diagnostic test for heparin-induced thrombocytopenia: detection of platelet microparticles using flow cytometry. Br J Haematol 1996;95:724.
15. Tomer A. A sensitive and specific functional flow cytometric assay for the diagnosis of heparin-induced thrombocytopenia. Br J Haematol 1997;98:648.
16. Lewis BE. Preliminary results of a prospective randomized controlled trial of argatroban vs. conventional therapy for heparin-induced thrombocytopenia. Presented at the Argatroban - A Novel Antithrombotic Drug for the Treatment of Heparin-Induced Thrombocytopenia Symposium, Florence, Italy, June 12, 1997.
17. Lewis BE, Rangel Y, Farced J. The first report of successful carotid stent implant using argatroban anticoagulation in a patient with heparin-induced thrombocytopenia and thrombosis syndrome. Angiology 1998;49:61.
18. Lewis BE, Walenga JM, Wallis DE. Anticoagulation with Novastan (argatroban) in patients with heparin-induced thrombocytopenia and heparin-induced thrombocytopenia thrombosis syndrome. Semin Thromb Hemost 1997;23:197.
19. Matthai WH. Use of argatroban during percutaneous coronary interventions in patients with heparin-induced thrombocytopenia. Semin Thromb Hemost 1999:25(Suppl 1):57.
20. Walenga JM, Jeske WP, Wood JJ, et al. Laboratory tests for heparin-induced thrombocytopenia: a multicenter study. Semin Hematol 1999;36(Suppl 1):22.
21. Chong BH, Burgess J, Ismail F. The clinical usefulness of the platelet aggregation test for the diagnosis of heparin-induced thrombocytopenia. Thromb Haemost 1993;69:344.
22. Isenhart CE, Brandt JT. Platelet aggregation studies for the diagnosis of heparin-induced thrombocytopenia. Coag Transfus Med 1992;99:324.
23. Warkentin TE, Chong BH, Greinacher A. Heparin-induced thrombocytopenia: towards consensus. Thromb Haemost 1998;79:1.
24. Walenga JM, Jeske WP, Fasanella AR, et al. Laboratory tests for the diagnosis of heparin-induced thrombocytopenia. Semin Thromb Hemost 1999;25(Suppl 1):43.
25. Brandt JT, Isenhart CE, Osborne JM, et al. On the role of platelet FcRIIa phenotype in heparin-induced thrombocytopenia. Thromb Haemost 1995;74:1564.
26. Jeske WP, Szatkowski E, Ero M, et al. Effect of heparinase on the in vitro response of platelets to HIT serum as measured by platelet aggregometry and flow cytometry. Blood 1997;90(Suppl 1):64b.
27. Pötzsch B, Keller M, Madlener K. The use of heparinase improves the specificity of cross-reactivity testing in heparin-induced thrombocytopenia. Thromb Haemost 1996;76:1121.
28. Izban KF, Lietz HW, Hoppensteadt DA, et al. Comparison of two PF4/heparin ELISA assays for the laboratory diagnosis of heparin-induced thrombocytopenia. Semin Thromb Hemost 1999;25(Suppl 1):51.
29. Walenga JM, Lewis BE, Hoppensteadt DA, et al. Management of heparin-induced thrombocytopenia and heparin-induced thrombocytopenia and thrombosis syndrome. Clin Appl Thromb Hemost 1997;2(Suppl 1):S53.
30. Shankey TV, Jeske WP, Walenga JM. Flow cytometric analysis of platelets and platelet function. In: Stewart C, Nicholson J, eds. Immunophenotyping. New York: John Wiley & Sons. 1999, (in press).
31. Jeske WP, Walenga JM, Szatkowski E, et al. Effect of glycoprotein IIb/IIIa antagonists on the HIT serum induced activation of platelets. Thromb Res 1997;88:271.
32. Jeske WP, Zaman S, Messmore HL, et al. Platelet pre-activation is not a primary mechanism for platelet activation in HIT. Blood 1998;92(Suppl 1):86b.
33. Lindhoff-Last E, Stein M, Spiegel J. Clinical relevance of heparin-platelet factor 4 antibodies in patients after vascular surgery. Ann Hematol 1997;74(Suppl II):A63.
34. 14C-serotonin release assay in the diagnosis of heparin-induced thrombocytopenia. Am J Clin Pathol 1995;104:648.