Pathogenesis of adynamic bone disease in chronic renal failure;Pathogenese der adynamen osteopathie bei chronischer niereninsuffizienz

Nieren- und Hochdruckkrankheiten

Volumn 28, Issue 10, 1999, Pages 379-385

  Reichel, H ^a,b   Benzing, C ^a  

^a SCHWARZWALD BAAR KLINIKUM   (Germany)

^b Dialyse Institut   (Germany)

Author keywords

Adynamic bone disease; Dialysis; Renal insufficiency; Renal osteodystrophy

Indexed keywords

CALCIUM PHOSPHATE; PARATHYROID HORMONE; PARATHYROID HORMONE RELATED PROTEIN;

AGING; BONE DISEASE; CALCIUM INTAKE; CHRONIC KIDNEY FAILURE; DIABETES MELLITUS; DISEASE ASSOCIATION; HUMAN; HYPERGLYCEMIA; HYPOPARATHYROIDISM; INSULIN DEFICIENCY; PATHOGENESIS; PERITONEAL DIALYSIS; REVIEW;

EID: 0032704439     PISSN: 03005224     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (36)

1. Aubia J., S. Serrano, L. Marinoso, L. Hojman, A. Diez, J. Loveras, J. Masramon: Osteodystrophy of diabetics in chronic dialysis: a histomorphometric study. Calcif. Tissue Int. 42, 297-301 (1988).
2. 3 administration in moderate renal failure: A prospective double-blind trial. Kidney Int. 35, 661-669 (1989).
3. Ballanti P., B.M. Wedard, E. Bonucci: Frequency of adynamic bone disease and aluminum storage in Italian uremic patients - retrospective analysis of 1429 iliac crest biopsies. Nephrol. Dial. Transplant. 11, 663-667 (1996).
4. Coen G., S. Mazzaferro, P. Ballanti, D. Sardella, S. Chicca, M. Manni, E. Bonucci, F. Taggi: Renal bone disease in 76 patients with varying degrees of predialysis chronic renal failure - a cross-sectional study. Nephrol. Dial. Transplant. 11, 813-819 (1996).
5. Couttenye M.M., P.C. D'Haese, J.T. Deng, V.O. Van Hoof, G.A. Verpooten, M.E. De Broe: High prevalence of adynamic bone disease diagnosed by biochemical markers in a wide sample of the European CAPD population. Nephrol. Dial. Transplant. 12, 2144-2150 (1997).
6. Faugere M.-C., M.C. Langub, Q. Qi, H.H. Malluche: Normal PTH/PTHrP receptor mRNA and protein in osteoblasts of patients with adynamic bone disease. J. Am. Soc. Nephrol. 9, 544A (1998).
7. Felsenfeld A.J., M. Rodriguez, R. Dunlay, F. Liach: A comparison of parathyroid gland function in hemodialysis patients with different forms of renal osteodystrophy. Nephrol. Dial. Transplant. 6, 244-251 (1991).
8. Ferreira A., P. Simon, T.B. Drücke, B. Descamps-Latscha: Potential role of cytokines in renal osteodystrophy. Nephrol. Dial. Transplant. 11, 399-400 (1996).
9. Gonzalez E.A., K.J. Martin: Coordinated regulation of PTH/PTHrP receptors by PTH and calcitriol in UMR 106-01 osteoblast-like cells. Kidney Int. 50, 63-70 (1996).
10. Hamdy N.A.T., J.A. Kanis, M.N.C. Beneton, C.B. Brown, J.R. Juttmann, J.G.M. Jodang, S. Josse, A. Meyner, R.L. Lins, I.T. Faircy: Effect of alfacalcidol on natural course of renal bone disease in mild-to- moderate renal failure. Br. Med. J. 310, 358-363 (1995).
11. Hercz G., Y. Pei, C. Greenwood, A. Manuel, C. Saiphoo, W.G. Goodman, G.V. Segre, S. Fenton, D.J. Sherrard: Aplastic osteodystrophy without aluminum: The role of "suppressed" parathyroid function. Kidney Int. 44, 860-866 (1993).
12. Hernandez D., M.T. Concepcion, V. Lorenzo, M.E. Martinez, A. Rodriguez, E. De Bonis, J.M. Gonzalez-Posada, A.J. Felsenfeld, M. Rodriguez, A. Torres: Adynamic bone disease with negative aluminum staining in predialysis patients: prevalence and evolution after maintenance dialysis. Nephrol. Dial. Transplant. 9, 517-523 (1994).
13. Kurz P., M.-C. Monier-Faugere, B. Bognar, E. Werner, P. Roth, J. Vlachojannis, H.H. Malluche: Evidence for abnormal calcium homeostasis in patients with adynamic bone disease. Kidney Int. 46, 855-861 (1994).
14. Kurz P., T. Tsobanelis, P. Roth, E. Werner, U. Ewald, P. Grützmacher, W. Shoeppe, J. Vlachojanins: Differences in calcium kinetic pattern between CAPD and HD patients. Clinical Nephrology 44, 255-261 (1995).
15. Langub M.C., N.J. Koszewski, H.V. Turner, M.-C. Monier-Faugere, Z. Geng, H.H. Malluche: Bone resorption and mRNA expression of IL-6 and IL-6 receptor in patients with renal osteodystrophy. Kidney Int. 50, 515-520 (1996).
16. Malluche H.H., M.-C. Faugere: Risk of adynamic bone disease in dialyzed patients. Kidney Int. 42 (Suppl. 38). S62-S67 (1992).
17. Massry S.G., M. Smogorzewski: PTH-PTHrP receptor in chronic renal failure. Nephrol. Dial. Transplant. 13, 50-57 (1998).
18. 3 intake: emergence of idiopathic adynamic bone disease not related to aluminum. Nephron 53, 93-101 (1989).
19. Olaizola I., A. Aznarez, V. Jorgetti, A. Petraglia, H. Caorsi, G. Acuna, L. Fajardo, P. Ambrosoni, N. Mazzuchi: Are there any differences in the parathyroid response in the different types of renal osteodystrophy? Nephrol. Dial. Transplant. 13, 15-18 (1998).
20. Pei Y., G. Hercz, C. Greenwood, G. Segre, A. Manuel, C. Saiphoo, S. Fenton, D. Sherrard: Risk factors for renal osteodystrophy: a multivariant analysis. J. Bone Miner. Res. 10, 149-156 (1995).
21. Picton M.L., R. Gokal, A.J. Hutchison, J. Hoyland: Uremic compounds and osteoblast expression of PTH/PTHrP mRNA. J. Am. Soc. Nephrol. 9, 548A (1998).
22. Quarles L.D., B. Lobaugh, G. Murphy: Intact parathyroid hormone overestimates the presence and severity of parathyroid mediated osseous abnormalities in uremia. J. Clin. Endocrinol. Metab. 75, 145-150 (1992).
23. Reichel H., C. Benzing: Unveröffentlichte Daten.
24. Rodriguez-Perez J.C., C. Plaza, A. Torres, N. Vega, A. Anabitarte, A. Fernandez, V. Lorenzo, L. Hortal, L. Palop: Low turnover bone disease is the more common form of bone disease in CAPD patients. Adv. Perit. Dial. 8, 376-380 (1992).
25. Salem M.M.: Hyperparathyroidism in the hemodialysis population: a survey of 612 patients. Am. J. Kidney Dis. 29, 862-865 (1997).
26. Sanchez C.P., W.G. Goodman, J.A. Ramirez, B. Gales, T.R. Belfin, G.V. Segre, I.B. Salusky: Calcium regulated parathyroid hormone secretion in adynamic renal osteodystrophy. Kidney Int. 48, 838-843 (1995).
27. Shearing C.H., J.P. Ashby, D.A. Hepburn, B.M. Fisher, B.M. Frier: Suppression of plasma intact parathyroid hormone levels during insulin-induced hypoglycemia in humans. J. Clin. Endocrinol. Metab. 74, 1270-1276 (1992).
28. Sherrard D.J., G. Hercz, Y. Pei, N.A. Maloney, C. Greenwood, A. Manuel, C. Saiphoo, S.S. Fenton, G.V. Segre: The spectrum of bone disease in end-stage renal failure - an evolving disorder. Kidney Int. 43, 436-442 (1993).
29. Smans K.A., G.F. Van Landeghem, P.C. D'Haese, M.M. Couttenye, M.E. De Broe: Is there a link between erythropoietin therapy and adynamic bone disease? Nephrol. Dial. Transplant. 11, 1248-1249 (1996).
30. Sugimoto T., C. Ritter, J. Morrissey, C. Hayes, E. Slatopolsky: Effects of high concentrations of glucose on PTH secretion in parathyroid cells. Kidney Int. 37, 1522-1527 (1990).
31. Torres A., V. Lorenzo, D. Hernandez, J.C. Rodriguez, M.T. Concepcion, A.P. Rodriguez, A. Hernandez, E. De Bonis, E. Darias, J.M. Gonzalez-Posada, M. Losada, M. Rufino, A.J. Felsenfeld, M. Rodriguez: Bone disease in predialysis, hemodialysis, and CAPD patients: evidence of a better bone response to PTH. Kidney Int. 47, 1434-1442 (1995).
32. Torres A., D. Hernandez, N. Barros, M. Rodriguez, V. Lorenzo, A.J. Felsenfeld: Decreased osteoblast response to PTH as a predisposing factor for adynamic bone disease (ABD) in older dialysis patients. J. Am. Soc. Nephrol. 9, 550A (1998).
33. Urena P., A. Ferreira, C. Morieux, T. Drüeke, M.C. de Vernejoul: PTH/PTHrP receptor mRNA is down-regulated in epiphyseal cartilage growth plate of uremic rats. Nephrol. Dial. Transplant. 11, 2008-2016 (1996).
34. Vincenti F., S.B. Arnaud, R. Recker, H. Genant, W.J.C. Amend Jr., N.J. Feduska, O. Salvatierra Jr.: Parathyroid and bone response of the diabetic patient to uremia. Kidney Int. 25, 677-682 (1984).
35. Weinreich T., J. Zapf, H. Schmidt-Gayk, H. Ritzel, G. Delling, H. Reichel: Insulin-like growth factor 1 and 2 serum concentrations in dialysis patients with secondary hyperparathyroidism and adynamic bone disease. Clin. Nephrol. 51, 27-33 (1999).
36. Wiske P.S., S. Epstein, N.H. Bell, S.F. Queener, J. Edmondson, C.C. Johnston Jr.: Increases in immunoreactive parathyroid hormone with age. N. Engl. J. Med. 300, 1419-1421 (1979).