Coordinate regulation of PTH/PTHrP receptors by PTH and calcitriol in UMR 106-01 osteoblast-like cells

Kidney International

Volumn 50, Issue 1, 1996, Pages 63-70

  González, Esther A ^a   Martin, Kevin J ^a  

^a SAINT LOUIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; CYCLIC AMP; PARATHYROID HORMONE; PARATHYROID HORMONE RECEPTOR; PARATHYROID HORMONE RELATED PROTEIN; PARATHYROID HORMONE[1-34];

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HORMONE RECEPTOR INTERACTION; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RAT;

EID: 0029787994     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1996.287     Document Type: Article

References (34)

1. MITCHELL J, GOLTZMAN D: Mechanisms of homologous and heterologous regulation of parathyroid hormone receptors in the rat osteosarcoma cell line UMR-106. Endocrinology 126:2650-2660, 1990
2. MARCUS R, ORNER FB: Cyclic AMP production in rat calvaria in vitro, interaction of prostaglandins, parathyroid hormone Endocrinology 101:1570-1578, 1977
3. 1, and calcitonin. Endocrinology 103:333-340, 1978
4. 2, calcitonin, and 1,25-dihydroxycholecalciferol. Endocrinology 107:1474-1481, 1980
5. PECK WA, KOHLER G: Hormonal and nonhormonal desensitization in isolated bone cells. Calcif Tissue Int 32:95-103, 1980
6. TEITELBAUM AP, SILVE GM, NYIREDY KO, ARNAUD CD: Down-regulation of parathyroid hormone (PTH) receptors in cultured bone cells is associated with agonist-specific intracellular processing of PTH-receptor complexes. Endocrinology 118:595-602, 1986
7. OLGAARD K, SCHWARTZ J, FINCO D, ARBELAEZ M, KORKOR A, MARTIN K, KLAHR S, SLATOPOLSKY E: Extraction of parathyroid hormone and release of adenosine 3′,5′-monophosphate by isolated perfused bones obtained from dogs with acute uremia. Endocrinology 111:1678-1682, 1982
8. FUJIMORI A, MIYAUCHI A, HRUSKA KA, MARTIN KJ, AVIOLI LV, CIVITELLI R: Desensitization of calcium messenger system in parathyroid hormone-stimulated opossum kidney cells. Am J Physiol 264: E918-E924, 1993
9. IKEDA K, SUGIMOTO T, FUKASE M, FUJITA T: Protein kinase C is involved in PTH-induced homologous desensitization by directly affecting PTH receptor in the osteoblastic osteosarcoma cells. Endocrinology 128:2901-2906, 1991
10. PERNALETE N, GARCIA JC, BETTS CR, MARTIN KJ: Inhibitors of protein kinase-C modulate desensitization of the parathyroid hormone receptor-adenylate cyclase system in opossum kidney cells. Endocrinology 126:407-413, 1990
11. ABOU-SAMRA AB, ZAJAC JD, SCHIFFER-ALBERTS D, SKURAT R, KEARNS A, SEGRE GV, BRINGHURST FR: Cyclic adenosine 3′,5′-monophosphate (cAMP)-dependent and cAMP-independent regulation of parathyroid hormone receptors on UMR 106-01 osteoblastic osteosarcoma cells. Endocrinology 129:2547-2554, 1991
12. ABOU-SAMRA AB, JUEPPNER H, POTTS JT JR, SEGRE GV: Inactivation of pertussis toxin-sensitive guanyl nucleotide-binding proteins increase parathyroid hormone receptors and reverse agonist-induced receptor down-regulation in ROS 17/2.8 cells. Endocrinology 125: 2594-2599, 1989
13. TAMAYO J, BELLORIN-FONT E, MARTIN KJ: Effects of dietary-induced hyperparathyroidism on the parathyroid hormone-receptor-adenylate cyclase system of canine kidney. J Clin Invest 72:422-432, 1983
14. HANAI H, LIANG CT, CHENG L, SACKTOR B: Desensitization to parathyroid hormone in renal cells from aged rats is associated with alteration in G-protein activity. J Clin Invest 83:268-277, 1989
15. 1-2α. Endocrinology 135:595-602, 1994
16. 3 on cyclic AMP responses to hormones in clonal osteogenic sarcoma cells. Biochem J 231:11-17, 1985
17. CATHERWOOD BD: 1,25-Dihydroxycholecalciferol and glucocorticosteroid regulation of adenylate cyclase in an osteoblast-like cell line. J Biol Chem 260:736-743, 1985
18. 3 on human osteoblast-like osteosarcoma cell: Modification of response to PTH. Biochem Biophys Res Com 168:889-897, 1990
19. UREN̄A P, IIDA-KLEIN A, KONG XF, JÜPPNER H, KRONENBERG HM, ABOU-SAMRA A-B, SEGRE GV: Regulation of parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acid by glucocorticoids and PTH in ROS 17/2.8 and OK cells. Endocrinology 134:451-456, 1994
20. UREN̄A P, MANNSTADT M, HRUBY M, FERREIRA A, SCHMITT F, SILVE C, ARDAILLOU R, LACOUR B, ABOU-SAMRA A-B, SEGRE GV, DRÜEKE T: Parathyroidectomy does not prevent the renal PTH/PTHrP receptor down-regulation in uremic rats. Kidney Int 47:1797-1805, 1995
21. TAMAYO J, BELLORIN-FONT E, SICARD G, ANDERSON C, MARTIN KJ: Desensitization to parathyroid hormone in the isolated perfused canine kidney: Reversal of altered receptor-adenylate cyclase system by guanosine triphosphate in vitro. Endocrinology 111:1311-1317, 1982
22. 3 suppresses PTH secretion from bovine parathyroid cells in tissue culture. Endocrinology 227:2114-2119, 1985
23. CHAN YL, MCKAY C, DYE E, SLATOPOLSKY E: The effect of 1,25-dyhydroxycholecalciferol on parathyroid hormone secretion by monolayer cultures of bovine parathyroid cells. Calcif Tissue Int 38:27-32, 1986
24. SILVER J, RUSSELL J, SHERWOOD LM: Regulation of vitamin D metabolites of messenger RNA for pre-proparathyroid hormone in isolated bovine parathyroid cells. Proc Natl Acad Sci USA 82:4270-4273, 1985
25. 3 of transcription of the parathyroid hormone gene. Endocrinology 119:2864-2866, 1986
26. SILVER J, NAVEH-MANY T, MAYER H, SCHMEIZER HJ, POPOVTZER MM: Regulation by vitamin D metabolites of parathyroid gene transcription in vitro in the rat. J Clin Invest 78:1296-1301, 1986
27. 3. J Biol Chem 263:2203-2208, 1988
28. OKANO K, WU S, HUANG X, PIROLA CJ, JÜPPNER H, ABOU-SAMRA A-B, SEGRE GV, IWASAKI K, FAGIN JA, CLEMENS TL: Parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor and its messenger ribonucleie acid in rat aortic vascular smooth muscle cells and UMR osteoblast-like cells; cell-specific regulation by angiotensin-II and PTHrP. Endocrinology 135:1093-1099, 1994
29. FUKAYAMA S, SCHIPANI E, JÜPPNER H, LANSKE E, KRONENBERG HM, ABOU-SAMRE AB, BRINGHURST FR: Role of protein kinase A in homologous down-regulation of parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acid in human osteoblast-like SaOS-2 cells. Endocrinology 134:1851-1858, 1994
30. UREN̄A P, KUBRUSLY M, MANNSTADT M, HRUBY M, TAN M-M, SILVE C, LACOUR B, ABOU-SAMRA A-B, SEGRE GV, DRÜEKE T: The renal PTH/PTHrP receptor is down-regulated in rats with chronic renal failure. Kidney Int 445:605-611, 1994
31. TIAN J, SMOGORZEWSKI M, KEDES L, MASSRY SG: PTH-PTHrP receptor mRNA is downregulated in chronic renal failure. Am J Nephrol 14:41-46, 1994
32. GOODMAN WG, RAMIREZ JA, BELIN TR, CHON Y, FALES B, SEGRE GV, SALUSKY IB: Development of adynamic bone in patients with secondary hyperparathyroidism after intermittent calcitriol therapy. Kidney Int 46:1160-1166, 1994
33. GONZÁLEZ EA, ZHONG M, BROWN AJ, MCCONKEY C, MARTIN KJ: Dietary calcium and calcitriol, but not the levels of parathyroid hormone (PTH), down-regulate PTH receptor mRNA in vitamin D deficient rats. (abstract) J Am Soc Nephrol 6:962, 1995
34. TURNER G, COUREAU C, RISZK RABIN M, ESCOUBET B, HRUBY M, WALRANT O, SILVE C: Parathyroid hormone (PTH)/PTH-Related protein receptor messenger ribonucleic acid expression and PTH response in a rat model of secondary hyperparathyroidism associated with vitamin D deficiency. Endocrinology 136:3751-3758, 1995