Is there a link between erythropoietin therapy and adynamic bone disease?

Nephrology Dialysis Transplantation

Volumn 11, Issue 7, 1996, Pages 1248-1249

  Smans, Karine A ^a   Van Landeghem, G F ^a   D'Haese, P C ^a   Couttenye, Marie M ^a   De Broe, M E ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; TRANSFERRIN RECEPTOR;

ANEMIA; DIALYSIS; HUMAN; KIDNEY FAILURE; PARATHYROID GLAND; PRIORITY JOURNAL; RENAL OSTEODYSTROPHY; SHORT SURVEY;

EID: 0029899356     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/11.7.1248     Document Type: Short Survey

References (13)

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3. Malluche HH, Monier-Faugere MC. Risk of adynamic bone disease in dialyzed patients. Kidney Int 1992; 42: S62-S67
4. 3 intake: emergency of an idiopathic adynamic bone disease not related to aluminum. Nephron 1989; 53: 93-101
5. Sherrard DJ, Hercz G, Pei Y et al. The spectrum of bone disease in end-stage renal failure-an evolving disorder. Kidney Int. 1993; 43: 436-442
6. Couttenye M-M, Vanuytsel JL, D'Haese PC, Verpooten GA, Van Hoof VO, Elseviers MM, De Broe ME. High prevalence of low bone turnover in dialysis (D). J Am Soc Nephrol 1991; 2: 610 (Abstract)
7. Goodman WJ, Ramirez JA, Belin JR et al. Development of adynamic bone in patients with secundary hyperparathyroidism after intermittent calcitriol therapy. Kidney Int. 1994; 46: 1160-1166
8. Eschbach JW, Downing MR, Egrie JC, Browne JK, Adamson JW. Multicenter Clinical Trial With Recombinant Human Erythropoietin. Contrib Nephrol 1989; 76: 160-165
9. Cannata JB, Fernández-Soto I, Fernández-Menendez MJ et al. Role of iron metabolism in absorption and cellular uptake of aluminum. Kidney Int 1991; 39: 799-803
10. Greger JL, Chang MM, Macneil Roudzanowski G. Comparison of tissue retention of aluminum and Ga-67: effects of iron status in rats. Toxicol 1995; 100: 1-9
11. Van Landeghem GF, D'Haese PC, Lamberts LV, De Broe ME. The affinity of transferrin for aluminum is inversely correlated with the iron-transferrin saturation. An explanation for the presence of aluminum overload in dialysis patients despite low serum aluminum levels. J Clin Invest (Submitted).
12. Kasai K, Hori MT, Goodman WG. Transferrin enhances the antiproliferative effect of aluminum on osteoblast-like cells. Am J Physiol Endocrinol Metab 1991; 260: E537-E543
13. Smans KA, D'Haese PC, Van Landeghem GF, Lamberts LV, De Broe ME. Aluminum transferrin (AlTf) but not Alcitrate (Alcit) uptake by the parathyroid gland (PTG) may contribute to the development of hypoparathyroidism associated with adynamic bone disease (ABD). J Am Soc Nephrol 1995; 6: 940 (Abstract)