Evaluation of quantal neurosecretion from evoked and miniature postsynaptic responses by deconvolution method

Journal of Neuroscience Methods

Volumn 92, Issue 1-2, 1999, Pages 91-99

  Vorobieva, Olga N ^a,c   Hackett, John T ^a   Worden, Mary Kate ^b   Bykhovskaia, Maria ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

Author keywords

Computer simulation; Multiple regression; Neuromuscular junction; Quantal analysis; Quantal content; Software; Synapse

Indexed keywords

ALGORITHM; ARTICLE; COMPUTER SIMULATION; COMPUTER SYSTEM; EVOKED MUSCLE RESPONSE; LOBSTER; MUSCLE INNERVATION; NERVE CELL MEMBRANE POTENTIAL; NEUROMUSCULAR SYNAPSE; NEUROTRANSMITTER RELEASE; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL;

ACTION POTENTIALS; ALGORITHMS; ANIMALS; EXCITATORY POSTSYNAPTIC POTENTIALS; NEPHROPIDAE; NEUROMUSCULAR JUNCTION; QUANTUM THEORY; REGRESSION ANALYSIS; SYNAPTIC VESICLES;

EID: 0032702706     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0270(99)00101-6     Document Type: Article

References (27)

1. Bekkers JM, Stevens CF. Quantal analysis of EPSPs recorded from small numbers of synapses in hippocampal cultures. J Neurophysiol 1995;73:1145-56.
2. Bekkers JM, Clements JD. Quantal amplitude and quantal variance of skontium-induced asynchronous EPSPs in rat dentate granule neurons. J Physiol 1999;516(1):227-48.
3. Bykhovskaia M, Worden MK, Hackett JT. An algorithm for high resolution detection of postsynaptic quantal events in extracellular records. J Neurosci Methods 1996;65:173-82.
4. Bykhovskaia M, Hackett JT, Worden MK. Asynchrony of quantal events in evoked multiquantal responses indicates presynaptic quantal interaction. J Neurophysiol 1999a;81:2234-42.
5. Bykhovskaia M, Worden MK, Hackett JT. Presynaptic facilitation: electrophysiology and computer simulations. Neurocomputing 1999b;26-27:9-15.
6. Bykhovskaia M, Worden MK, Hackett JT. Stochastic modeling of facilitated neurosecretion. J Comput Neurosci 1999c; in press.
7. Bykhovskaia M, Polagaeva E, Vorobieva O, Hackett JT. Hyperosmolarity suppresses presynaptic facilitation but enhances stimulus-uncoupled neurosecretion. Soc Neurosci Abstr 1999d;25: 473.
8. Cooper RL, Marin L, Atwood HL. Synaptic differentiation of a single motor neuron: conjoint definition of transmitter release, presynaptic calcium signals and ultra structure. J Neurosci 1995;15:4209-22.
9. Frerking M, Gorges S, Wilson M. Variation in GABA mini amplitude is the consequence of variation in transmitter concentration. Neuron 1995;18:885-95.
10. Frerking M, Wilson M. Effects of variance in mini amplitude on stimulus-evoked release: a comparison of two models. Biophys J 1996;70:2078-91.
11. Frerking M, Borges S, Wilson M. Are some minis multiquantal? J Neurophysiol 1997;78:1293-304.
12. Gruber MHJ. Improving Efficiency by Shrinkage. The James-Stein and Ridge Regression Estimators. New York: Marcel Dekker, 1998.
13. Isaacson JS, Walmsley B. Amplitude and time course of spontaneous and evoked excitory postsynaptic currents in bushy cells of the anteroventral cochlear nucleus. J Neurophysiol 1996;76(3):1566-71.
14. Katz B, Miledi R. Propagation of electric activity in motor nerve terminals. Proc R Soc B 1965;161:453-82.
15. Kullmann DM. Applications of the expectation-maximization algorithm to quantal analysis of postsynaptic potentials. J Neurosci Methods 1989;30:231-45.
16. Montgomery DC, Peck EA. Introduction to Linear Regression Analysis. New York: Wiley, 1992.
17. Niles W, Smith DO. Effects of hypertonic solutions on quantal transmitter release at the crayfish neuromuscular junction. J Physiol 1982;329:185-202.
18. Nusser Z, Cull-Candy S, Farrant M. Differences in synaptic GABA receptor number underlie variation in GABA mini amplitude. Neuron 1997;19:697-709.
19. Oliet SHR, Malenka RC, Nocoll RA. Bidirectional control of quantal size by synaptic activity in the hippocampus. Science 1996;271:1294-7.
20. Redman S. Quantal analysis of synaptic potentials in neurons of the central nervous system. Physiol Rev 1990;70:165-98.
21. Smith BR, Wojtowicz JM, Atwood HL. Maximum likelihood estimation of non-uniform transmitter release probabilities at the crayfish neuromuscular junction. J Theor Biol 1991;150:457-72.
22. Stricker C, Redman S. Statistical models of synaptic transmission evaluated using the expectation-maximization algorithm. Biophys J 1994;67:656-70.
23. Stricker C, Redman S, Daley D. Statistical analysis of synaptic transmission: model discrimination and confidence limits. Biophys J 1994;67:532-655.
24. Stevens CF, Wesseling JF. Activity-dependent modulation of the rate at which synaptic vesicles become available to undergo exocytosis. Neuron 1998;21:415-24.
25. Van der Kloot W. The regulation of quantal size. Prog Neurobiol 1991;36:91-130.
26. Worden MK, Bykhovskaia M, Hackett JT. Facilitation at the lobster neuromuscular junction: a stimulus dependent mobilization model. J Neurophysiol 1997;78:417-28.
27. Zucker RS. Changes in the statistics of transmitter release during facilitation. J Physiol 1973;229:787-810.