Evidence for TIMP-1 protection against P. aeruginosa-induced corneal ulceration and perforation

Investigative Ophthalmology and Visual Science

Volumn 40, Issue 13, 1999, Pages 3168-3176

  Kernacki, Karen A ^a   Barrett, Ronald ^a   Hazlett, Linda D ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; POLYCLONAL ANTIBODY; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; CORNEA PERFORATION; CORNEA ULCER; EXTRACELLULAR MATRIX; GRAM NEGATIVE INFECTION; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA;

ANIMALS; CORNEA; CORNEAL ULCER; EYE INFECTIONS, BACTERIAL; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; NEUTROPHILS; PEROXIDASE; PSEUDOMONAS INFECTIONS; RABBITS; RECOMBINANT PROTEINS; RNA, MESSENGER; RUPTURE, SPONTANEOUS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TISSUE INHIBITOR OF METALLOPROTEINASE-3;

EID: 0032699524     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Hyndiuk RA. Experimental Pseudomonas keratitis. Trans Am Ophthalmol. 1981;79:541-624.
2. Hendricks RL, Tumpey TM, Finnegan A. IFN-γ and IL-2 are protective in the skin hut pathologic in corneas of HSV-1 infected mice. J Immunol. 1992;149:3023-3028.
3. Brown SI, Wasserman HE, Dunn MW. Alkali-burn of the cornea. Arch Ophthalmol. 1969;82:91-94.
4. Kenyon KR, Fogle JA, Stone DL, Stark WJ. Regeneration of corneal epithelial basement membrane following thermal cauterization. Invest Ophthalmol Vis Sci. 1977;16:292-301.
5. Hazelman BL, Watson PG. Ocular complications of rheumatoid arthritis. Clin Rheum Dis. 1977;3:501-526.
6. Twining S, Wilson PM, Hatchell DL. Characterization of corneal proteoglycans under vitamin A deficiency. Biochem Biophys Acta. 1989;992:181-190.
7. Seng WL, Glogowski JA, Wolf G, Herman MB, Kenyon KR, Kiorpes TC. The effects of thermal burn on the release of collagenase from the cornea. Invest Ophthalmol Vis Sci. 1980;19:1461-1470.
8. Hazlett LD, Zelt R, Cramer C, Berk RS. Pseudomonas aeruginosa ocular infection. A histological comparison of two bacterial strains. Ophthalmic Res. 1985;17:289-296.
9. Pahlitzsch T, Sinha P. The alkali-burned cornea: electron microscopical, enzyme histochemical and biochemical observations Graefs Arch Clin Exp Ophthalmol. 1985;223:278-286.
10. Herman MB, Kenyon K, Hayashi K, L'Hernault N. The Pathogenesis of Epithelial Defects in Stromal ulceration. Cavanaugh HD, ed. New York: Raven Press; 1988:35-43.
11. Berman MB. Collagenase in Normal and Pathological Connective Tissues. Wooley DE, Chichester JM, eds. New York: Wiley; 1980: 141-174.
12. Kenyon KR, Berman M, Rose J, Gage J. Prevention of stromal ulceration in the alkali-burned cornea by glued-on contact lens. Evidence for the role of polymorphonuclear leukocytes in collagen degradation. Invest Ophthalmol Vis Sci. 1979;18:570-587.
13. Steuhl K-P, Doring G, Henni A, Thiel H-J. Botzenhart K. Relevance of host-derived and bacterial factors in Pseudomonas aeruginosa corneal infections. Invest Ophthalmol Vis Sci. 1987;28:1559-1568.
14. Hobden JA, Masinick SA, Barrett RP, Hazlett LD. Proinflammatory cytokine deficiency and the pathogenesis of Pseudomonas aeruginosa keratitis in aged mice. Infect Immun. 1997;65:2754-2758.
15. Paterson CA, Wells JC, Koklitis PA, Higgs GA, Docherty AJ. Recombinant tissue inhibitor of metalloproteinases suppresses alkali-burn-induced corneal ulceration. Invest Ophthalmol Vis Sci. 1994; 35:677-684.
16. Wentworth JS, Paterson CA, Gray RD. Effect of a metalloproteinase inhibitor on established corneal ulcers. Invest Ophthalmol Vis Sci. 1992;33:2174-2179.
17. Barletta JP, Angella G, Balch K, Dimora HG, Stern GA, Moser MT. Inhibition of Pseudomonal ulceration in rabbit corneas by a synthetic matrix metalloproteinase inhibitor. Invest Ophthalmol Vis Sci. 1996;37:20-28.
18. Fini ME, Parks WC, Rinehart WB, et al. Role of matrix metalloproteinases in failure to re-epithelialize after corneal injury. Am J Pathol. 1996;65:579-586.
19. Schultz GS, Strelow S, Stern GA, et al. Treatment of alkali-injured rabbit corneas with a synthetic inhibitor of matrix metalloproteinases. Invest Ophthalmol Vis Sci. 1992;33:3325-3331.
20. Riley GP, Harall RL, Watson PG, Cawston TE, Hazelman BL. Collagenase (MMP-1) and TIMP-1 in destructive corneal disease associated with rheumatoid arthritis Eye. 1995;9:703-718.
21. Ries C, Petrides PE. Cytokine regulation of matrix metalloproteinase activity and its regulatory dysfunction in disease. Biol Chem. 1995;376:345-355.
22. Cawston TE. Metalloproteinase inhibitors and the prevention of connective tissue breakdown. Pharmacol Ther. 1996;70:163-182.
23. Leco KJ, Apte SS, Taniguchi GT, et al. Murine tissue inhibitor of metalloproteinase-4 (TIMP-4): cDNA isolation and expression in adult mouse tissues. FEBS Lett. 1997;401:213-217.
24. Opbroek A, Kenney MC, Brown D. Characterization of a human corneal metalloproteinase inhibitor (TIMP-1). Curr Eye Res. 1993; 12:877-883.
25. Kenney MC, Chwa M, Opbroek AJ, Brown DJ. Increased gelatinolytic activity in keratoconus cultures: a correlation to an altered matrix metalloproteinase-2/tissue inhibitor of metalloproteinase ratio. Cornea. 1994;13:114-124.
26. Kenney MC, Chwa M, Alba A, Saghizadeh M, Huang ZS, Brown DJ. Localization of TIMP-1, TIMP-2, TIMP-3, gelatinase A and gelatinase B in pathological human corneas. Curr Eye Res. 1998;17:238-246.
27. Kernacki KA, Goebel DJ, Poosch MS, Hazlett LD. Early TIMP gene expression after corneal infection with Pseudomonas aeruginosa. Invest Ophthalmol Vis Sci. 1998;36:1371-1378.
28. Kwon B, Hazlett LD. Association of CD4+ T-cell dependent keratitis with genetic susceptibility to Pseudomonas aeruginosa ocular infection. J Immunol. 1997;159:6283-6290.
29. Hazlett LD, Moon MM, Strejc M, Berk RS. Evidence for N-acetylmannosamine as an ocular receptor for P. aeruginosa adherence to scarified cornea. Invest Ophthalmol Vis Sci. 1987;28:1978-1985.
30. Negro A, Onisto M, Grassato L, Caenazzo C, Garbisa S. Recombinant TIMP-3 from Escherichia coli: synthesis, refolding, physiochemical and functional insights. Protein Eng. 1997;10:593-599.
31. Kernacki KA, Berk RS. Characterization of arachidonic acid metabolism and the polymorphonuclear leukocyte response in mice infected intracorneally with Pseudomonas aeruginosa. Invest Ophthalmol Vis Sci. 1995;36:16-23.
32. Williams RN, Paterson CA, Eakins KE. Quantitation of ocular inflammation: evaluation of polymorphonuclear leukocyte inflammation by measuring myeloperoxidase activity. Curr Eye Res. 1983;2:465-471.
33. Hobden JA, Masinick SA, Barrett RP, Hazlett LD. Aged mice fail to upregulate ICAM-1 after Pseudomonas aeruginosa corneal infection. Invest Ophthalmol Vis Sci. 1995;36:1107-1114.
34. Denhardt DT, Feng B, Edwards DR, Cocuzzi ET, Malyankar UM. Tissue inhibitor of metalloproteinases (TIMP, aka EPA): structure, control of expression and biological functions. Pharmacol Ther. 1993;59:329-341.
35. Borden P, Heller RA. Transcriptional control of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases. Crit Rev Euk Gene Exp. 1997;7:159-178.
36. Ashcroft GS, Herrick SE, Tarnuzzer RW, et al. Human ageing impairs injury-induced in vivo expression of tissue inhibitor of matrix metalloproteinases (TIMP)-1 and -2 proteins and mRNA. J Pathol. 1997;183:169-176.
37. Gipson TS, Bless NM, Shanley TP, et al. Regulatory effects of endogenous protease inhibitors in acute lung inflammatory injury. J Immunol. 1999;162:3653-3662.
38. Saika S, Kawashima Y, Okada Y, et al. Recombinant TIMP-1 and -2 enhance the proliferation of rabbit corneal epithelial cells in vitro and the spreading of rabbit corneal epithelium in situ. Curr Eye Res. 1998;17:47-52.
39. Treibel S, Blaser J, Gote T, et al. Evidence for the tissue of inhibitor of metalloproteinase-1 (TIMP-1) in human polymorphonuclear leukocytes. Eur J Biochem. 1995;231:714-719.
40. Pfister RR, Haddox JL, Sommers CI. Injection of chemoattractants into normal cornea: a model of inflammation after alkali injury. Invest Ophthalmol Vis Sci. 1998;39:1744-1750.
41. Bakowski B, Tschesche H. Migration of polymorphonuclear leukocytes through human amnion membrane-a scanning electron microscopic study. Biol Chem Hoppe-Seyler. 1992;343:529-546.
42. Bennett TA, Lynam EB, Sklar LA, Rogeli S. Hydroxamate-based metalloprotease inhibitor blocks shedding of L-selectin adhesion molecule from leukocytes. Functional consequences for neutrophil aggregation. J Immunol. 1996;156:3093-3097.
43. Pfister RR, Haddox JL, Sommers CI. Effect of a synthetic metalloproteinase inhibitor or citrate on neutrophil chemotaxis and the respiratory burst. Invest Ophthalmol Vis Sci. 1997;38:1340-1349.