Injection of chemoattractants into normal cornea: A model of inflammation after alkali injury

Investigative Ophthalmology and Visual Science

Volumn 39, Issue 9, 1998, Pages 1744-1750

  Pfister, Rosivell R ^a,b   Hadclox, Jeffrey L ^a   Sommers, Charnell I ^a  

^a Brookwood Medical Center Birmingham   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; ARTICLE; CAUSTIC BURN; CELL INFILTRATION; CORNEA EDEMA; CORNEA EPITHELIUM; CORNEA INJURY; KERATITIS; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; BURNS, CHEMICAL; CHEMOTACTIC FACTORS; CHEMOTAXIS, LEUKOCYTE; CORNEAL STROMA; DISEASE MODELS, ANIMAL; EYE BURNS; HUMANS; INJECTIONS; KERATITIS; LEUKOCYTE COUNT; LEUKOTRIENE B4; NEUTROPHILS; OLIGOPEPTIDES; RABBITS; SODIUM HYDROXIDE;

EID: 0031859054     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Kenyon KR, Herman M, Rose J, Gage J. Prevention of stromal ulceration in the alkali-burned rabbit cornea by gluecl-on contact lens. Evidence for the role of polymorphonuclear leukocytes in collagen degradation. Invest Ophthalmol Vis Sei. 1979;18:570-587.
2. Foster CS, Zelt RP, Mai-Phan T, Kenyon KR. Immunosuppression and selective inflammatory cell depletion. Studies of a guinea pig model of corneal ulcération after ocular alkali burning. Arch Opbtbalmol. 1982;100:1820-1824.
3. Pfister RR, Haddox JL, Sommers CI, Lam K-W. Identification and synthesis of chemotactic tripeptides from alkali-degraded whole cornea: a study of N-acetyl-proline-glycine-proIine and N-methyl-proline-glycine-proline. Imvst Ophthalmol Vis Set. 1995;36:1306-1316.
4. Pfister RR, Haddox JL. A neutrophil chemoattractant is released from cellular and extracellular components of the alkali-degraded cornea and blood. Invest Opbtbalmol Vis Sei. 1996;37:230-237.
5. Pfister RR, Haddox JL, Harkins LE, Dodson RW. The effects of citrate on fMLP induced polymorphonuclear leukocyte stimulation and locomotion. Cornea. 1984/1985;3:183-188.
6. Haston WS, Shields JM. Neutrophil leukocyte chemotaxis: a simplified assay for measuring polarizing responses to chemotactic factors. J Immunol Methods. 1985;81:229-237.
7. Ben-Zvi A, Rodrigucs M, Gery I, Scchiffmann E. Induction of inflammation by synthetic mediators. In: Suran A, Gery I, Nussenblatt RB, eds. Proceedings of the Immunology of the Eye Workshop, III: immunologic aspects of ocular diseases: infection, inflammation, and allergy (Abstracts). 1981:245-258.
8. Paterson CA, Williams RN, Parker AV. Characteristics of polymorphonuclear infiltration into the alkali burned eye and the influence of sodium citrate. Exp Eye Res. 1984:39:701-708.
9. Pfister RR, Haddox JL, Lam KAV. Alkali-degraded cells generate a respiratory burst stimulant for neutropliils. Cornea 1993:12:155-160.
10. Bazan HEP, Reddy STK, Lin N. Platelet-activating factor (PAF) accumulation correlates with injury in the cornea. Exp Eye Res. 1991;52:481-491.