Induction of the metabolism of midazolam by rifampin in cultured porcine hepatocytes: Preliminary evidence for CYP3A isoforms in pigs

Drug Metabolism and Disposition

Volumn 27, Issue 12, 1999, Pages 1512-1518

  Hosagrahara, Vinayak P ^a,c   Hansen, Linda K ^b   Remmel, Rory P ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; MESSENGER RNA; MIDAZOLAM; POLYCLONAL ANTIBODY; RIFAMPICIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG POTENTIATION; ENZYME INDUCTION; IMMUNOBLOTTING; LIVER CELL; MALE; NONHUMAN; NORTHERN BLOTTING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SWINE;

ANIMALS; ANTIBIOTICS, ANTITUBERCULAR; ARYL HYDROCARBON HYDROXYLASES; CELLS, CULTURED; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DEXAMETHASONE; ENZYME INDUCTION; HUMANS; ISOENZYMES; LIVER; MIDAZOLAM; OXIDOREDUCTASES, N-DEMETHYLATING; RATS; RIFAMPIN; RNA, MESSENGER; SUBSTRATE SPECIFICITY; SWINE;

EID: 0032698252     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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