Mutagenesis of SNM1, which encodes a protein component of the yeast RNase MRP, reveals a role for this ribonucleoprotein endoribonuclease in plasmid segregation

Molecular and Cellular Biology

Volumn 19, Issue 11, 1999, Pages 7857-7869

  Cai, Ti ^a   Reilly, Tracey R ^a   Cerio, Michael ^a   Schmitt, Mark E ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL RNA; RIBONUCLEASE; RIBONUCLEOPROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; DNA REPLICATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; RNA PROCESSING; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRAIN DIFFERENCE; TRANSLATION REGULATION;

SACCHAROMYCES CEREVISIAE;

EID: 0032696246     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.19.11.7857     Document Type: Article

References (61)

1. Allmang, C., Y. Henry, J. P. Morrissey, H. Wood, E. Petfalski, and D. Tollervey. 1996. Processing of the yeast pre-rRNA at sites A(2) and A(3) is linked. RNA 2:63-73.
2. Baldacci, G., B. Chérif-Zahar, and G. Bernardi. 1984. The initiation of DNA replication in the mitochondrial genome of yeast. EMBO J. 3:2115-2120.
3. Cerio, M., and M. E. Schmitt. Unpublished data.
4. Chamberlain, J. R., Y. Lee, W. S. Lane, and D. R. Engelke. 1998. Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP. Genes Dev. 12:1678-1690.
5. Chang, D. D., and D. A. Clayton. 1987. A mammalian mitochondrial RNA processing activity contains nucleus-encoded RNA. Science 235:1178-1184.
6. Chang, D. D., and D. A. Clayton. 1987. A novel endoribonuclease cleaves at a priming site of mouse mitochondrial DNA replication. EMBO J. 6:409-417.
7. Chang, D. D., and D. A. Clayton. 1989. Mouse RNAase MRP RNA is encoded by a nuclear gene and contains a decamer sequence complementary to a conserved region of mitochondrial RNA substrate. Cell 56:131-139.
8. Chu, S., R. H. Archer, J. M. Zengel, and L. Lindahl. 1994. The RNA of RNase MRP is required for normal processing of ribosomal RNA. Proc. Natl. Acad. Sci. USA 18:659-663.
9. Chu, S., J. M. Zengel, and L. Lindahl. 1997. A novel protein shared by RNase MRP and RNase P. RNA 3:382-391.
10. Clayton, D. A. 1994. A nuclear function for RNase MRP. Proc. Natl. Acad. Sci. USA 91:4615-4617.
11. Dichtl, B., and D. Tollervey. 1997. Pop3p is essential for the activity of the RNase MRP and RNase P. EMBO J. 16:417-429.
12. Dunn, B., P. Szauter, M. L. Pardue, and J. W. Szostak. 1984. Transfer of yeast telomeres to linear plasmids by recombination. Cell 39:191-201.
13. Felici, F., G. Cesareni, and J. M. X. Hughes. 1989. The most abundant small cytoplasmic RNA of Saccharomyces cerevisiae has an important function required for normal growth. Mol. Cell. Biol. 9:3260-3268.
14. Firoozan, M., C. M. Grant, J. A. Duarte, and M. F. Tuite. 1991. Quantitation of readthrough of termination codons in yeast using a novel gene fusion assay. Yeast 7:173-183.
15. Forster, A. C., and S. Altman. 1990. Similar cage-shaped structure for the RNA components of all ribonuclease P and ribonuclease MRP enzymes. Cell 62:407-409.
16. Gietz, R., and A. Sugino. 1988. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74:527-534.
17. Hardy, C. F., and A. Pautz. 1996. A novel role for Cdc5p in DNA replication. Mol. Cell. Biol. 16:6775-6782.
18. Henry, Y., H. Wood, J. P. Morrissey, E. Petfalski, S. Kearsey, and D. Tollervey. 1994. The 5′ end of yeast 5.8S rRNA is generated by exonucleases from an upstream cleavage site. EMBO J. 13:2452-2463.
19. Hill, J. H., A. M. Meyers, T. J. Koerner, and A. Tzagoloff. 1986. Yeast/E. coli shuttle vectors with multiple unique restriction sites. Yeast 2:163-167.
20. Hogan, E., and D. Koshland. 1992. Addition of extra origins of replication to a minichromosome suppresses its mitotic loss in cdc6 and cdc14 mutants of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 89:3098-3102.
21. Jacobson, M. R., L. G. Cao, Y. L. Wang, and T. Pederson. 1995. Dynamic localization of RNase MRP RNA in the nucleolus observed by fluorescent RNA cytochemistry in living cells. J. Cell Biol. 131:1649-1658.
22. Kilmartin, J. V., B. Wright, and C. Milstein. 1982. Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line. J. Cell Biol. 93:576-582.
23. Kopczynski, J. B., A. C. Raff, and J. J. Bonner. 1992. Translational readthrough at nonsense mutations in the HSF1 gene of Saccharomyces cerevisiae. Mol. Gen. Genet. 234:369-378.
24. Lee, D. Y., and D. A. Clayton. 1996. Properties of a primer RNA-DNA hybrid at the mouse mitochondrial DNA leading-strand origin of replication. J. Biol. Chem. 271:24262-24269.
25. Lee, D. Y., and D. A. Clayton. 1997. RNase mitochondrial RNA processing correctly cleaves a novel R loop at the mitochondrial DNA leading-strand origin of replication. Genes Dev. 11:582-592.
26. Lee, D. Y., and D. A. Clayton. 1998. Initiation of mitochondrial DNA replication by transcription and R-loop processing. J. Biol. Chem. 273:30614-30621.
27. Li, K., C. S. Smagula, W. J. Parsons, J. A. Richardson, M. Gonzalez, H. K. Hagler, and R. S. Williams. 1994. Subcellular partitioning of MRP RNA assessed by ultrastructural and biochemical analysis. J. Cell Biol. 124:871-882.
28. Liebman, S. W., F. Sherman, and J. W. Stewart. 1976. Isolation and characterization of amber suppressors in yeast. Genetics 82:251-272.
29. Lygerou, Z, C. Allmang, D. Tollervey, and B. Seraphin. 1996. Accurate processing of a eukaryotic precursor ribosomal RNA by ribonuclease MRP in vitro. Science 272:268-270.
30. Lygerou, Z., P. Mitchell, E. Petfalski, B. Seraphin, and D. Tollervey. 1994. The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins. Genes Dev. 8:1423-1433.
31. Markwell, M. A. K., S. M. Haas, L. L. Bieter, and N. E. Tolbert. 1978. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal. Biochem. 87:206-210.
32. Marmorstein, R., M. Carey, M. Ptashne, and S. C. Harrison. 1992. DNA recognition by GAL4: structure of a protein-DNA complex. Nature 356:408-414.
33. Morrissey, J. P., and D. Tollervey. 1995. Birth of the snoRNPs: the evolution of RNase MRP and the eukaryotic pre-rRNA-processing system. Trends Biochem. Sci. 20:78-82.
34. Mortimer, R. K., and R. A. Gilmore. 1968. Suppressors and suppressible mutations in yeast. Adv. Biol. Med. Phys. 12:319-331.
35. Muhlrad, D., R. Hunter, and R. Parker. 1992. A rapid method for localized mutagenesis of yeast genes. Yeast 8:79-82.
36. Paluh, J. L., and D. A. Clayton. 1996. A functional dominant mutation in Schizosaccharomyces pombe RNase MRP RNA affects nuclear RNA processing and requires the mitochondrial-associated nuclear mutation pip1-1 for viability. EMBO J. 15:4723-4733.
37. Pringle, J. R., R. A. Preston, E. M. Adams, T. Sterns, D. G. Drubin, B. K. Haarer, and E. W. Jones. 1989. Fluorescence microscopy methods for yeast. Methods Cell Biol. 31:357-435.
38. Reddy, R., and S. Shimba. 1995-1996. Structural and functional similarities between MRP and RNase P. Mol. Biol. Rep. 22:81-85.
39. Reilly, T. H., and M. E. Schmitt. 1995-1996. The yeast, Saccharomyces cerevisiae, RNase P/MRP ribonucleoprotein endoribonuclease family. Mol. Biol. Rep. 22:87-93.
40. Reimer, G., I. Raska, V. Scheer, and E. M. Tan. 1988. Immunolocalization of 7-2 ribonucleoprotein in the granular component of the nucleolus. Exp. Cell Res. 176:117-128.
41. Rose, M., P. Novick, J. H. Thomas, D. Botstein, and G. R. Fink. 1987. A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene 60:237-243.
42. Rubin, G. M. 1974. Three forms of the 5.8S ribosomal RNA species in Saccharomyces cerevisiae. Eur. J. Biochem. 41:197-202.
43. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
44. Schmitt, M. E., and D. A. Clayton. 1992. Yeast site-specific ribonucleoprotein endoribonuclease MRP contains an RNA component homologous to mammalian RNase MRP RNA and essential for cell viability. Genes Dev. 6:1975-1985.
45. Schmitt, M. E., and D. A. Clayton. 1993. Nuclear RNase MRP is required for correct processing of pre-5.8S rRNA in Saccharomyces cerevisiae. Mol. Cell. Biol. 13:7935-7941.
46. Schmitt, M. E., and D. A. Clayton. 1994. Isolation of a unique protein component of the yeast RNase MRP: an RNA-binding protein with a zinc-cluster domain. Genes Dev. 8:2617-2628.
47. Schmitt, M. E., J. L. Bennett, D. J. Dairaghi, and D. A. Clayton. 1993. Secondary structure of RNase MRP RNA as predicted by phylogenetic comparison. FASEB J. 7:208-213.
48. Schmitt, M. E., T. A. Brown, and B. L. Trumpower. 1990. A rapid, improved method for isolation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res. 18:3091-3092.
49. Sherman, F. 1991. Getting started with yeast. Methods Enzymol. 194:3-21.
50. Shou, W., J. H. Seol, A. Shevchenko, C. Baskerville, D. Moazed, Z. W. S. Chen, J. Jang, A. Shevchenko, H. Charbonneau, and R. J. Deshaies. 1999. Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. Cell 97:233-244.
51. Sikorski, R. S., and J. D. Boeke. 1991. In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast. Methods Enzymol. 194:302-318.
52. Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
53. Stohl, L. L., and D. A. Clayton. 1992. Saccharomyces cerevisiae contains an RNase MRP that cleaves at a conserved mitochondrial RNA sequence implicated in replication priming. Mol. Cell. Biol. 12:2561-2569.
54. Stolc, V., and S. Altman. 1997. Rpp1, an essential protein subunit of nuclear RNase P required for processing of precursor tRNA and 35S precursor rRNA in Sacchammyces cerevisiae. Genes Dev. 11:2414-2425.
55. 6 binuclear cluster. Nat. Struct. Biol. 4:751-759.
56. Tavernarakis, N., D. Alexandraki, P. Liodis, D. Tzamarias, and G. Thireos. 1996. Gene overexpression reveals alternative mechanisms that induce GCN4 mRNA translation. Gene 179:271-277.
57. Toyn, J. H., and L. H. Johnston. 1993. Spo12 is a limiting factor that interacts with the cell cycle protein kinases Dbf2 and Dbf20, which are involved in mitotic chromatid disjunction. Genetics 135:963-971.
58. Van Dyck, E., and D. A. Clayton. 1998. Transcription-dependent DNA transactions in the mitochondrial genome of a yeast hypersuppressive petite mutant. Mol. Cell. Biol. 18:2976-2985.
59. Visintin, R., E. Hwang, and A. Amon. 1999. Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus. Nature 398:818-823.
60. Wickner, R. B. 1996. Prions and RNA viruses of Saccharomyces cerevisiae. Annu. Rev. Genet. 30:109-139.
61. Xu, B., and D. A. Clayton. 1995. A persistent RNA-DNA hybrid is formed during transcription at a phylogenetically conserved mitochondrial DNA sequence. Mol. Cell. Biol. 15:580-589.