Abnormal colonic endocrine cells in patients with chronic idiopathic slow-transit constipation

Scandinavian Journal of Gastroenterology

Volumn 34, Issue 10, 1999, Pages 1007-1011

  El Salhy, M ^a,b   Norrgård, Ö ^a   Spinnell, S ^a  

^a University Hospital   (Sweden)

^b UMEÅ UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Colon; Computerized image analysis; Endocrine cells; Immunohistochemistry; Serotonin; Slow transit constipation

Indexed keywords

OXYNTOMODULIN; PANCREAS POLYPEPTIDE; PEPTIDE YY; SEROTONIN; SOMATOSTATIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COLON MOTILITY; COLON MUCOSA; CONSTIPATION; CONTROLLED STUDY; ENDOCRINE CELL; FEMALE; GASTROINTESTINAL TRANSIT; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMMUNOCYTOCHEMISTRY; MALE; PRIORITY JOURNAL; SECRETORY CELL;

ADULT; AGED; BIOPSY; CHRONIC DISEASE; COLON; COLONIC DISEASES, FUNCTIONAL; CONSTIPATION; ENTEROENDOCRINE CELLS; FEMALE; GASTROINTESTINAL MOTILITY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; PEPTIDE YY; SEROTONIN; STATISTICS, NONPARAMETRIC;

EID: 0032694284     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/003655299750025110     Document Type: Article

References (36)

1. 1. MacDonald A, Baxter JN, Finlay IG. Idiopathic slow-transit constipation. Br J Surg 1993;80:1107-11.
2. 2. Klauser AG, Peyerl C, Schindbeck NE, Müller-Lissner SA. Nutrition and physical activity in chronic constipation. Eur J Gastroenterol Hepatol 1992;4:227-33.
3. 3. Preston DM, Lenard-Jones JE. Severe chronic constipation of young women: 'idiopathic slow transit constipation'. Gut 1986; 27:41-8.
4. 4. Bassotti G, Gaburri M, Imbimbo BP, Rossi L, Faroni F, Pelli MA, et al. Colonic mass movement in idiopathic chronic constipation. Gut 1988;29:1173-8.
5. 5. Bassotti G, Betti C, Pelli MA, Morelli A. Prolonged (24-hours) manometeric recording of rectal contractile activity in patients with slow transit constipation. Digestion 1991;49:72-7.
6. 6. Bazzocchi G, Ellis J, Meyer J, Mena I, Reddy SN, Morento-Osset E. Colonic scintigraphy and manometry in constipation, diarrhoea and inflammatory bowel disease [abstract]. Gastroenterology 1988;94:A29.
7. 7. Dyer NH, Dawson AM, Smith BF. Obstruction of the bowel due to lesion in myenteric plexus. Br Med J 1969;1:686-9.
8. 8. Kune G. Megacolon in adults. Br J Surg 1966;53:199-205.
9. 9. Smith B, Grace RH, Todd IP. Organic constipation in adults. Br J Surg 1977;64:313-4.
10. 10. Koch TR, Carney JA, Go L, Go V. Idiopathic chronic constipation is associated with decreased colonic vasoactive intestinal peptide. Gastroenterology 1988;94:300-10.
11. 11. Milner P, Crowe R, Kamm MA, Lennard-Jones JE, Burnstock G. Vasoactive intestinal polypeptide levels in sigmoid colon in idiopathic constipation and diverticular disease. Gastroenterology 1990;99:666-75.
12. 12. Lincoln J, Crowe R, Kamm MA, Burnstock G, Lennard-Jones JE. Serotonin and 5-hydroxyindoleacetic acid increased in sigmoid colon in severe idiopathic constipation. Gastroenterology 1990;98:1219-25.
13. 13. Dolk A, Broden G, Holmström B, Johansson C, Schultzberg M. Slow transit chronic constipation (Arbuthnot Lane's disease). An immunohistochemical study of neuropeptide-containing nerves in resected specimens from the large bowel. Int J Colorectal Dis 1990;5:181-7.
14. 14. Cortesini C, Cianchi F, Infantino A, Lise M. Nitricoxide synthase and VIP distribution in enteric nervous system in idiopathic chronic constipation. Dig Dis Sci 1995;40:2450-5.
15. 15. Tavella K, Riepl RL, Klauser AG, Voderholzer WA, Schindbeck NE, Müller-Lissner SA. Decreased substance P levels in rectal biopsies from patients with slow transit constipation. Eur J Gastrenterol Hepatol 1996;8:1207-11.
16. 16. Ekblad E, Håkanson R, Sundler F. Microanatomy and chemical coding of peptide-containing neurones in the digestive tract. In: Daniel EE, editor. Neuropeptides function in gastrointestinal tract. Boca Raton (FL): CRC Press; 1991. p. 131-80.
17. 17. Allescher HD, Ahmed S. Postulated pathophysiological roles in motility. In: Daniel EE, editor. Neuropeptides function in gastrointestinal tract. Boca Raton (FL): CRC Press; 1991. p. 309-400.
18. 18. Rangachari PK. Effects of neuropeptides on intestinal ion transport. In: Daniel EE, editor. Neuropeptides function in gastrointestinal tract. Boca Raton (FL): CRC Press; 1991. p. 429-46.
19. 19. Abrahamsson H, Antov S, Bosaeus I. Gastrointestinal and colonic transit time evaluated by a single abdominal X-ray in healthy subjects and constipated patients. Scand J Gastroenterol 1988;23 Suppl 152:72-80.
20. 20. El-Salhy M, Suhr O. Endocrine cells in rectal biopsy specimens from patients with familial amyloidotic polyneuropathy. Scand J Gastroenterol 1996;31:68-73.
21. 21. El-Salhy M, Sandström O, Näsström E, Mustajbasic M, Zachrisson S. Application of computer image analysis in endocrine cell quantification. Histochem J 1997;29:249-56.
22. 22. Altmore D, Pilot MA, Wiliams N, Rubino M, Ilincic L, Waldrom D. Detection of subclinic autonomic neuropathy in constipated patients using a sweat test. Gut 1992;33:1539-43.
23. 23. Bassotti G, Chiarioni G, Limbimbo BP, Betti C, Bonfante F, Vantini I, et al. Impaired colonic motor response to cholinergic stimulation in patients with severe chronic idiopathic (slow transit type) constipation. Dig Dis Sci 1993;38:1040-5.
24. 24. Smith B. Effect of irritant purgatives on the myenteric plexus in man and mouse. Gut 1968;9:139-43.
25. 25. Smith B. Pathologic changes in the colon produced by anthraquinone purgatives. Dis Colon Rectum 1973;16:455-8.
26. 26. Reinmann JF, Schmidt H, Zimmerman W. The fine structure of colonic submucosal nerves in patients with chronic laxatives abuse. Scand J Gastroenterol 1980;15:761-8.
27. 27. Tavella K, Schenkirsch G, Riepl RL, Odenthal KP, Leng-Pesschow E, Müller-Lissner SA. Effects of long-term treatment with anthranoids and sodium picosulphate on the contents of vasoactive intestinal polypeptide, somatostatin and substance Pin the rat colon. Eur J Gastroenterol Hepatol 1995;7:13-20.
28. 28. El-Salhy M, Mahdavi J, Norrgård Ö. Colonic endocrine cells in patients with carcinoma of the colon. Eur J Gastroenterol Hepatol 1998;10:517-22.
29. 29. El-Salhy M, Norrgård Ö. Franzén L, Forsgren S. Colonic endocrine cells in patients with carcinoma of the rectum with special regard to preoperative irradiation. GI Cancer 1998;2: 285-92.
30. 30. Lidberg P. On the role of substance P and serotonin in the pyloric motor control. An experimental study in cat and rat. Acta Physiol Scand 1985;Suppl 538:1-69.
31. 31. Goarard DA, Libby GW, Farthing MJ. 5-Hydroxytryptamine and human intestinal motility: effect of inhibiting 5-hydroxytryptamine uptake. Gut 1994;35:496-500.
32. 32. Tally NJ. Review article: 5-hydroxytryptamine agonists and antagonists in modulation of gastrointestinal motility and sensation: clinical implications. Aliment Pharmacol Ther 1992; 6:273-89.
33. 33. von der Ohe MR, Hanson RB, Camilleri M. Serotogenic mediation of postprandial colonic tonic and phasic response in humans. Gut 1994;35:536-41.
34. 34. Oosterbusch L, von der Ohe MR, Valdovinos MA, Kost LJ, Phillips SF, Camilleri M. Effects of serotonin on rat ileocolonic transit and fluid transfer in vivo: possible mechanisms of action. Gut 1993;34:794-8.
35. 35. Walsh JH. Gastrointestinal hormones; enteroglucagons. In: Johnson LR, Alpers DH, Christensen J, Jacobson ED, Walsh JH, editors. Physiology of the gastrointestinal tract. 3rd ed. New York: Raven Press; 1994. p. 95-106.
36. 36. Jonston JC, Shaw C, Buchanan KD. Vincristine-induced abnormalities of gastrointestinal regulatory peptide cells of the rat. An immunocytochemical study. Cell Tissue Res 1985;239: 229-33.