Colonic endocrine cells in patients with carcinoma of the colon

European Journal of Gastroenterology and Hepatology

Volumn 10, Issue 6, 1998, Pages 517-522

  El Salhy, Magdy ^a   Mahdavi, Jafar ^a   Norrgård, Örjan ^a  

^a UMEÅ UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Adenocarcinoma; Colon; Computer image analysis; Endocrine cells; Immunohistochemistry; Serotonin; Somatostatin

Indexed keywords

AVIDIN; BIOTIN; SEROTONIN; SOMATOSTATIN;

ADULT; AGED; ARTICLE; CELL SECRETION; CLINICAL ARTICLE; COLON ADENOCARCINOMA; CONTROLLED STUDY; ENDOCRINE CELL; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL;

EID: 0031776974     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-199806000-00015     Document Type: Article

References (36)

1. Hill DJ. Neuropeptides and cell proliferation. In: Neuropeptides function in gastrointestinal tract. Daniel EE, editor. Boca Raton: CRC Press, 1991: 479-490.
2. Narayan S, Guo YS, Townsend CM Jr, Singh P. Specific binding and growth effects of bombesin-related peptides on mouse colon cancer cells in vitro. Cancer Res 1990; 50:6772-6778.
3. Fucht H, Gadzar AF, Park JA, Olie H, Jensen RT. Characterization of functional receptors for gastrointestinal hormones on human colon cancer cells. Cancer Res 1992; 52:1114-1122.
4. Radulovic SS, Milovanovic SR, Cai RZ, Schally AV. The binding of bombesin and somatostatin and their analogs to human cancers. Proc Soc Exp Biol Med 1992; 200:394-401.
5. Chicone L, Narayan S, Townsend CM Jr, Singh P. The presence of a 33-40 kDa gastrin binding protein on human and mouse colon cancer. Biochem Biophys Res Commun 1989; 164:512-519.
6. Upp JR, Singh P, Townsend CM Jr, Thompson JC. Clinical significance of gastrin receptors in human colon cancers. Cancer Res 1989; 49:488-492.
7. Couvineau A, Roussel M, Laburthe M. Molecular identification and structural requirement of vasoactive intestinal peptide (VIP) receptors in the human colon adenocarcinoma cell line, HT-29. Biochem J 1985; 231:139-143.
8. Maoret JJ, Popsai D, Rouyer-Fessard C, Couvineau A, Laboisse C, Voisin T, Laburth M. Neurotensin receptors and mRNA are expressed in many human colon cancer cell lines but not in normal colonic epithelium: binding studies and RT-PCR experiments. Biochem Biophys Commun 1994; 203:465-471.
9. Cox HM. Receptors for calcitonin gene related peptide (CGRP) in gastrointestinal epithelial cells. Can J Physiol Pharmacol 1995; 73:974-980.
10. Smith JP, Solomon TE. Effects of gastrin, proglumide, somatostatin on growth of human colon cancer. Gastroenterology 1988; 95:1541-1548.
11. Alonos M, Galera MJ, Reyes G, Calabuig R, Vinals A, Rius X. Effects of pentagastrin and somatostatin analog (SMS 201-995) on growth of CT26 in vivo adenocarcinoma of the colon. Surg Gynecol Obstet 1992; 175:441-444.
12. Guo YS, Baijal M, Jin GF, Thompson JC, Townsend CM Jr, Singh P. Growth-promoting effects of gastrin on mouse colon cancer cells in vitro: absence of autocrine effects. In vitro Cell Dev Biol 1990; 26:871-877.
13. Lamote J, Willems G. Stimulating effect of pentagastrin on cancer cell proliferation kinetics in chemically induced colon cancer in rats. Regul Pept 1988; 20:1-9.
14. Kusyk CJ, McNeil NO, Johnson LR. Stimulation of growth of colon cancer cell line by gastrin. Am Physiol 1986; 251:597-601.
15. Winsett OE, Townsend CM Jr, Glass CJ, Thompson JC. Gastrin stimulates growth of colon cancer. Surgery 1986; 99:302-307.
16. Yoshinaga K, Evers BM, Izukura M, Parekh D, Townsend CM Jr, Thompson JC. Neurotensin stimulates growth of colon cancer. Surg Oncol 1992; 1:127-134.
17. Tasuta M, Ishi H, Baba M, Taniguchi H. Enhancement by neurotensin of experimental carcinogenesis induced in rat colon by azoxymethane. Br J Cancer 1990; 62:368-371.
18. Robbins RJ. Somatostatin and cancer. Metab Clin Exp 1996; 45:98-100.
19. Di-Paolo A, Bocci G, Innocenti F, Agen C, Nardini, D, Danesi R, Del-Tacca M. Inhibitory effect of somatostatin analogue SMS 201-995 and cytokines on the proliferation of human colon adenocarcinoma cell lines. Pharmacol Res 1995; 32:135-139.
20. Stewart GJ, Connor JL, Lawson A, Preketes A, King J, Morris JL. Octreotide reduces the kinetic index, proliferating cell nuclear antigen-maximum proliferative index, in patients with colorectal cancer. Cancer 1995; 76:572-578.
21. Radulovic S, Schally AV, Reile H, Halmos G, Szepeshazi K, Groot K, Milovanovic S, Miller G, Tang T. Inhibitory effects of antagonists of bombesin/gastrin releasing peptide (GRP) and somatostatin analog (RC-160) on growth of TH-29 human colon cancers in nude mice. Acta Oncol 1994; 33:693-701.
22. Ruszniewski P, Lehy T, Reyl-Desmars F, Le-Roux S, Lewin MJM. Octreotide (SMS 201-995) inhibits the growth of colon peritoneal carcinomatosis in Bodix rats. Regul Pep 1993; 43:141-147.
23. Qin Y, Schally AV, Willems G. Treatment of liver metatases of human colon cancer in nude mice with somatostatin analogue RC-160. Int J Cancer 1992; 52:791-796.
24. Dy DY, Whitehead RH, Morris DL. SMS 201.995 inhibits in vitro and in vivo growth of human colon cancer. Cancer Res 1992; 52:917-923.
25. Garnet L, Murat JC, Remaury A, Remesy C, Valet P, Paris H, Denis-Pouxviel C. Vasoactive intestinal peptide and forskolin regulate proliferation of HT29 human colon adenocarcinoma cell line. J Cell Physiol 1992; 150:501-509.
26. van-Tol EA, Verspaget HW, Pena AS, Jansen JB, Aparicio-Pages MN, Lambers CB. Modulatory effects of VIP and related peptides from gastrointestinal tract on cell mediated cytotoxicity against tumor cells in vitro. Immunol Invest 1991; 20:257-267.
27. Lishi H, Tatsuta M, Baba M, Uehara H, Yano H, Nakaizumi A. Chemoprevention by galanin against colon carcinogenesis induced by azoxymethane in Wistar rats. Int J Cancer 1995; 61:861-863.
28. El-Salhy M, Mahdavi J, Norrgård Ö. Low levels of colonic somatostatin and galanin in patients with colon carcinoma. Gl Cancer, in press.
29. El-Salhy M, Suhr O. Endocrine cells in rectal biopsy specimens from patients with familial amyloidotic polneuropathy. Scand J Gastroenterol 1996; 31:68-73.
30. El-Salhy M, Sandström O, Näsström E, Mustajbasic M, Zachrisson S. Application of computer image analysis in endocrine cell quantification. Histochem J 1997; 29:249-256.
31. Pinto HC, Portela-Gomes GM, Grimelius L, Kohnert K-D, De Sousa JC, Albuquerque AMP. The distribution of endocrine cell types of the gastrointestinal mucosa in genetically diabetic (db/db) mice. Gastroenterology 1995; 108:967-974.
32. Ekblad E, Håkanson R, Sundler F. Microanatomy and chemical coding of peptide-containing neurones in the digestive tract. In: Neuropeptides function in gastrointestinal tract. Daniel EE, editor. Boca Raton: CRC Press, 1991. pp. 131-180.
33. Sgambati SA, Zarif A, Basson MD. Octreotide differentially modulates human Caco-2 intestinal epithelial cell proliferation and differentiation by decreasing intracellular cAMP. Regul Pept 1996; 61:219-227.
34. Hajri A, Aprahamian M, Damgé C. Effect of prolonged administration of long acting somatostatin on caeurlin, CCK-8 and GRP induced pancreatic growth in the rat. Regul Pept 1991; 32:227-237.
35. Tutton PJ, Barkta DH. The influence of serotonin on mitotic rate in the colonic crypt epithelium and in colonic adenocarcinoma in rats. Clin Exp Pharmacol Physiol 1978; 5:91-94.
36. Bold RJ, Ishizuka J, Townsend CM Jr. Progress toward hormonal therapy of gastrointestinal cancer. Ann Surg 1996; 223:4-11.