Application of computer image analysis in endocrine cell quantification

Histochemical Journal

Volumn 29, Issue 3, 1997, Pages 249-256

  El Salhy, M ^a   Sandstrom O ^a   Nasstrom E ^a   Mustajbasic, M ^a   Zachrisson, S ^a  

^a UMEÅ UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOGRANIN; SECRETIN;

ADULT; AGED; ARTICLE; DUODENUM; ENDOCRINE CELL; FEMALE; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; VOLUMETRY;

ADULT; CHROMOGRANIN A; CHROMOGRANINS; DUODENUM; ENDOCRINE GLANDS; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; SECRETIN;

EID: 0030943514     PISSN: 00182214     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026458027425     Document Type: Article

References (33)

1. ALLESCHER, H.D. & AHMED, S. (1990) Postulated physiological and pathophysiological roles on motility. In Neuropeptides Function in Gastrointestinal Tract (edited by DANIEL, E.D.), pp. 309-400. Boston: CRC Press.
2. BISHOP, A.E., POLAK, J.M., BRYANT, M.G., BLOOM, S.R. & HAMILTON, S. (1980) Abnormalities of vasoactive intestinal polypeptide-containing nerves in Crohn's disease. Gastroenterology 79, 853-60.
3. CETIN, Y. (1992) Chromogranin A immunoreactivity and Grimelius argyrophilia. A correlative study in mammalian endocrine cells. Anat. Embryol. 185, 207-15.
4. EKBLADE, E., HÅKANSSON, R. & SUNDLER, F. (1990) Microanatomy and chemical coding of peptide-containing neurones in the digestive tract. In Neuropeptides Function in Gastrointestinal Tract (edited by DANIEL, E.D.), pp. 131-80. Boston: CRC Press.
5. EL-SALHY, M. & SUHR, O. (1996) Endocrine cells in rectal biopsy specimens from patients with familial amyloidosis and polyneuropathy. Scand. J. Gastroenterol. 31, 68-73.
6. EL-SALHY, M., STENLING, R. & GRIMELIUS, L. (1993) Peptidergic nerves and endocrine cells in the human liver. Scand. J. Gastroenterol. 28, 809-15.
7. EL-SALHY, M., SUHR, O., STENLING, R., WILANDER, E. & GRIMELIUS, L. (1994) Impact of familial amyloid associated polyneuropathy on the duodenal endocrine cells. Gut 35, 1413-8.
8. EL-SALHY, M., DANIELSSON, Å, STENLING, R. & GRIMELIUS, L. (1996) Colonie endocrine cells in inflammatory bowel disease. J. Intern. Med. (submitted).
9. FACER, P., BISHOP, A.E., LLOYD, R.V., WILSON, B.S., HENNESSY, R.J. & POLAK, J.M. (1985) Chromogranin: a newly recognized marker for endocrine cells of human gastrointestinal tract. Gastroenterology 89, 1366-73.
10. FERRI, G.-L., VEZZADINI, P., LABO, G. & POLAK, J.M. (1983) The use of crypt suspension for endocrine cell quantification. Histochem. J. 15, 1251-3.
11. GUNDERSEN, H.J.G. (1978) Estimators of the number of objects per area unbiased by edge effects. Microscop. Acta 81, 107-17.
12. GUNDERSEN, H.J.G. (1986) Stereology of arbitrary particles. A review on unbiased number and size estimators and presentation of some new ones, in memory of Wiliam R. Thompson. J. Microscop. 143, 3-45.
13. GUNDERSEN, H.J.G. & ÖSTERBERG, R. (1981) Optimizing sampling efficiency of stereological studies in biology: or 'do more less well'. J. Microscop. 121, 65-73.
14. GUNDERSEN, H., BAGGER, P., BENDSTEN, T.F., EVANS, S.M., KORBO, L., MARCUSSEN, N., MÖLLER, A., NIELSEN, K., NYEGAARD, J.R., PAKKENBERG, B., SORENSEN, F.B., VESTERBY, A. & WEST, M.J. (1988) The new stereological tools: dissector, fractionator, nucleator and point sampled intercepts and their use in pathological research. APMIS 96, 857-81.
15. HARVEY, R.F. (1975) Hormonal control of gastrointestinal motility. Am. J. Dig. Dis., 20, 523-9.
16. HENNING, A. (1959) A critical survey of volume and surface measurements in microscopy. Zeiss-Werkz. 30, 1-8.
17. HUIZINGA, J.D. & PINTIN-QUEAZADA, J. (1990) Physiological and pathophysiological roles of VIP, somatostatin, opoids, galanin, GRP, and secretin. In Neuropeptides Function in Gastrointestinal Tract (edited by DANIEL, E.D.) pp. 401-28. Boston: CRC Press.
18. KOCH, T.R., CARNEY, J.A. & GO, V.L.W. (1987) Distribution and quantitation of gut neuropeptides in normal and inflammatory bowel disease. Dig. Dis. Sci. 32, 369-376.
19. KOCH, T.R., CARNEY, J.A., MORRIS, V.A. & GO, V.L.W. (1988a) Somatostatin in the idiopathic inflammatory bowel disease. Dis. Colon Rectum 31, 198-203.
20. KOCH, T.R., MICHENER, S.R., CARNEY, J.A. & GO, V.L.W. (1988b) Decreased colonie peptide histamine-methionin in idiopathic inflammatory disease. Dig. Dis. Sci. 33, 423-8.
21. KUBOTA, Y., PETERS, R.E., OTTAWAY, C.A., TUBBS, R.R., FARMER, R.G. & FIOCCHI, C. (1992) Colonic vasoactive intestinal peptide nerves in inflammatory bowel disease. Gastroenterology 102, 1242-51.
22. MULDER, H., AHRÉN, B. & SUNDLER, F. (1995) Recent advances in localization and quantification of gene expression - a lesson from islet amyloid polypeptide. Cell Vis. 2, 94-103.
23. O'DORISIO, M.S. (1987) Neuropeptides and gastrointestinal immunity. Am. J. Med. 81 (Suppl. 6B), 74-82.
24. O'MORAIN, C., BISHOP, A., MCGREGOR, G.P., LEVI, A.J., BLOOM, S.R., POLAK, J.M. & PETERS, T.J. (1984) Vasoactive intestinal peptide concentrations and immunocytochemical studies in rectal biopsies from patients with inflammatory bowel disease. Gut 25, 57-61.
25. RANGACHARI, P.K. (1990) Effects of neuropeptides on intestinal ion transport. In Neuropeptides Function in Gastrointestinal Tract (edited by DANIEL, E.D.), pp. 429-46. Boston: CRC Press.
26. RÖNNBLOM, A., DANIELSSON, Å. & EL-SALHY, M. (1996) Intestinal endocrine cells in myotonic dystrophy: an immunocytochemical and computed image analytical study. Gut (submitted).
27. SJÖLUND, K., MUCKADELL, O.B.S., FAHRENKRUG, J., HAKANSSON, R., PETERSON, B.G. & SUNDLER, F. (1983a) Peptide containing nerve fibres in the gut wall in Crohn's disease. Gut 24, 724-33.
28. SJÖLUND, K., SANDÉN, G., HÅKANSSON, R. & SUNDLER, F. (1983b) Endocrine cells in human intestine. An immunocytochemical study. Gastroenterology 85, 1120-30.
29. STERIO, D. (1984) The unbiased estimation of number and sizes of arbitrary particles using dissector. J. Microscop. 134, 127-36.
30. WEIBEL, E. & ELIAS, H. (1967a) Quantitative methods in morphology. Berlin: Springer-Verlag.
31. WEIBEL, E.R. & ELIAS, H. (1967b) Introduction to stereologic principles. In Quantitative Methods in Morphology (edited by WEIBEL, E.R. & ELIAS, H.), pp. 89-98. Berlin: Springer-Verlag.
32. WEIBEL, E., STÄUBLI, R.H. & HESS, F.A. (1969) Correlated morphometric and biochemical studies on the liver cell. I. Morphometric model, stereologic methods, and normal morphometric data for rat liver. J. Cell Biol. 42, 68-91.
33. WEST, M., SOLOMIANKA, L. & GUNDERSEN, H.J.G. (1991) Unbiased stereological estimation of the total number of neurones in the subdivision of the rat hypocampus using optical fractionator. Anat. Rec. 231, 482-97.