Control of meiotic recombination and gene expression in yeast by a simple repetitive DNA sequence that excludes nucleosomes

Molecular and Cellular Biology

Volumn 19, Issue 11, 1999, Pages 7661-7671

  Kirkpatrick, David T ^a   Wang, Yuh Hwa ^a,b   Dominska, Margaret ^a   Griffith, Jack D ^a   Petes, Thomas D ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; POLYNUCLEOTIDE; TRANSCRIPTION FACTOR;

ALLELE; ARTICLE; DNA SEQUENCE; GENETIC RECOMBINATION; MEIOSIS; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TANDEM REPEAT;

EUKARYOTA; FUNGI; MYXOGASTRIA; SACCHAROMYCES CEREVISIAE;

EID: 0032694088     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.11.7661     Document Type: Article

References (53)

1. Alani, E., R. Padmore, and N. Kleckner. 1990. Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination. Cell 61:419-436.
2. Arndt, K. T., C. Styles, and G. R. Fink. 1987. Multiple global regulators control HIS4 transcription in yeast. Science 237:874-880.
3. Detloff, P., J. Sieber, and T. D. Petes. 1991. Repair of specific base pair mismatches formed during meiotic recombination in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:737-745.
4. Detloff, P., M. A. White, and T. D. Petes. 1992. Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae. Genetics 132:113-123.
5. Devlin, C., K. Tice-Baldwin, D. Shore, and K. T. Arndt. 1991. RAP1 is required for BAS1/BAS2-and GCN4-dependent transcription of the yeast HIS4 gene. Mol. Cell. Biol. 11:3642-3651.
6. Egel, R. 1984. Two tightly-linked silent cassettes in the mating-type region of Schizosaccharomyces pombe. Curr. Genet. 8:199-203.
7. Ekwall, K., and T. Ruusala. 1994. Mutations in rik1, clr2, clr3, and clr4 asymmetrically derepress the silent mating-type loci in fission yeast. Genetics 136:53-64.
8. Fan, Q.-Q., F. Xu, and T. D. Petes. 1995. Meiosis-specific double-strand DNA breaks at the HIS4 recombination hot spot in the yeast Saccharomyces cerevisiae: control in cis and trans. Mol. Cell. Biol. 15:1679-1688.
9. Fan, Q.-Q., and T. D. Petes. 1996. Relationship between nuclease-hypersensitive sites and meiotic recombination hot spot activity at the HIS4 locus of Saccharomyces cerevisiae. Mol. Cell. Biol. 16:2037-2043.
10. Fan, Q.-Q., F. Xu, M. A. White, and T. D. Petes. 1997. Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae. Genetics 145:661-670.
11. Goyon, C., and M. Lichten. 1993. Timing of molecular events in meiosis in Saccharomyces cerevisiae: stable heteroduplex DNA is formed late in meiotic prophase. Mol. Cell. Biol. 13:373-382.
12. Griffith, J. 1975. Chromatin structure: deduced from a mini-chromosome. Science 187:1202-1203.
13. Guthrie, C., and G. R. Fink (ed.). 1991. Guide to yeast genetics and molecular biology. Academic Press, Inc., San Diego, Calif.
14. Hartzog, G. A., and F. Winston. 1997. Nucleosomes and transcription: recent lessons from genetics. Curr. Opin. Genet. Dev. 7:192-198.
15. Iyer, V., and K. Struhl. 1995. Poly(dA:dT), a ubiquitous promoter element that stimulates transcription via its intrinsic DNA structure. EMBO J. 14: 2570-2579.
16. Jayasena, S. D., and M. J. Behe. 1989. Competitive nucleosome reconstitution of polydeoxynucleotides containing oligoguanosine tracts. J. Mol. Biol. 208:297-306.
17. Kirkpatrick, D. T., Q.-Q. Fan, and T. D. Petes. 1999. Maximal stimulation of meiotic recombination by a yeast transcription factor requires the transcription activation domain and a DNA binding domain. Genetics 152:101-115.
18. Klar, A. J. S. 1992. Molecular genetics of fission yeast cell type: mating type and mating-type interconversion, p. 745-777. In E. W. Jones, J. R. Pringle, and J. R. Broach (ed.), The molecular and cellular biology of the yeast Saccharomyces, vol. 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
19. Kon, N., M. D. Krawchuk, B. G. Warren, G. R. Smith, and W. P. Wahls. 1997. Transcription factor Mts1/Mts2 (Atf1/Pcr1, Gad7/Pcr1) activates the M26 meiotic recombination hotspot in Schizosaccharomyces pombe. Proc. Natl. Acad. Sci. USA 94:13765-13770.
20. Kornberg, R. D. 1977. Structure of chromatin. Annu. Rev. Biochem. 46:931-954.
21. Kornberg, R. D., and Y. Lorch. 1992. Chromatin structure and transcription. Annu. Rev. Cell Biol. 8:563-589.
22. Lambie, E., and G. S. Roeder. 1986. Repression of meiotic crossing-over by a centromere (CEN3) in Saccharomyces cerevisiae. Genetics 114:769-789.
23. Lambie, E. J., and G. S. Roeder. 1988. A yeast centromere acts in cis to inhibit meiotic gene conversion of adjacent sequences. Cell 52:863-873.
24. Lichten, M., and A. S. H. Goldman. 1995. Meiotic recombination hotspots. Annu. Rev. Genet. 29:423-444.
25. Mavrothalassitis, G. J., D. K. Watson, and T. S. Papas. 1990. The human ETS-2 gene promoter: molecular dissection and nuclease hypersensitivity. Oncogene 5:1337-1342.
26. Nag, D. K., M. A. White, and T. D. Petes. 1989. Palindromic sequences in heteroduplex DNA inhibit mismatch repair in yeast. Nature 340:318-320.
27. Nagawa, F., and G. R. Fink. 1985. The relationship between the "TATA" sequence and transcription initiation sites at the HIS4 gene of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 82:8557-8561.
28. Ohta, K., T. Shibata, and A. Nicolas. 1994. Changes in chromatin structure at recombination initiation sites during yeast meiosis. EMBO J. 13:5754-5763.
29. Perkins, D. 1949. Biochemical mutants in the smut fungus Ustilago maydis. Genetics 34:607-626.
30. Petes, T. D., R. E. Malone, and L. S. Symington. 1991. Recombination in yeast, p. 407-521. In J. R. Broach, E. W. Jones, and J. R. Pringle (ed.), The molecular and cellular biology of the yeast Saccharomyces, vol. 1. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
31. Rhodes, D. 1979. Nucleosome cores reconstituted from poly(dA-dT) and the octamer of histones. Nucleic Acids Res. 6:1805-1816.
32. Roeder, G. S. 1997. Meiotic chromosomes: it takes two to tango. Genes Dev. 11:2600-2621.
33. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
34. Schultes, N. P., and J. W. Szostak. 1991. A poly(dA-dT) tract is a component of the recombination initiation site at the ARG4 locus in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:322-328.
35. Shimada, T., K. Inokuchi, and A. W. Nienhuis. 1986. Chromatin structure of the human dihydrofolate reductase gene promoter. J. Biol. Chem. 261:1445-1452.
36. Shrader, T. E., and D. M. Crothers. 1989. Artificial nucleosome positioning sequences. Proc. Natl. Acad. Sci. USA 86:7418-7422.
37. Solomon, F., L. Connell, D. Kirkpatrick, V. Praitis, and B. Weinstein. 1992. Methods for studying the cytoskeleton in yeast, p. 197-221. In K. L. Carraway and C. A. C. Carraway (ed.), The cytoskeleton: a practical approach. IRL Press, New York, N.Y.
38. Stapleton, A., and T. D. Petes. 1991. The Tn3 β-lactamase gene acts as a hotspot for meiotic recombination in yeast. Genetics 127:39-51.
39. Struhl, K. 1995. Yeast transcriptional regulatory mechanisms. Annu. Rev. Genet. 29:651-674.
40. Sun, H., D. Treco, N. P. Schultes, and J. W. Szostak. 1989. Double-strand breaks at an initiation site for meiotic gene conversion. Nature 338:87-90.
41. Symington, L. S., and T. D. Petes. 1988. Meiotic recombination within the centromere of a yeast chromosome. Cell 52:237-240.
42. Szostak, J. W., T. L. Orr-Weaver, R. J. Rothstein, and F. W. Stahl. 1983. The double-strand-break-repair model for recombination. Cell 33:25-35.
43. Thon, G., A. Cohen, and A. J. S. Klar. 1994. Three additional linkage groups that repress transcription and meiotic recombination in the mating-type region of Schizosaccharomyces pombe. Genetics 138:29-38.
44. Tice-Baldwin, K., G. R. Fink, and K. T. Arndt 1989. BAS1 has a Myb motif and activates HIS4 transcription only in combination with BAS2. Science 246:931-935.
45. Tsukiyama, T., and C. Wu. 1997. Chromatin remodeling and transcription. Curr. Opin. Genet. Dev. 7:182-191.
46. n motif: a common DNA repeat that excludes nucleosomes. Proc. Natl. Acad. Sci. USA 93: 8863-8867.
47. Wang, Y.-H., R. Gellibolian, M. Shimizu, R. D. Wells, and J. D. Griffith. 1996. Long CCG triplet repeats exclude nucleosomes: a possible mechanism for the nature of fragile sites in chromosomes. J. Mol. Biol. 263:511-516.
48. White, M. A., P. Detloff, M. Strand, and T. D. Petes. 1992. A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast. Curr. Genet. 21:109-116.
49. White, M. A., M. Dominska, and T. D. Petes. 1993. Transcription factors are required for the meiotic recombination hotspot at the HIS4 locus in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 90:6621-6625.
50. While, M. A., M. Wierdl, P. Detloff, and T. D. Petes. 1991. DNA-binding protein RAP1 stimulates meiotic recombination at the HIS4 locus in yeast. Proc. Natl. Acad. Sci. USA 88:9755-9759.
51. Wijgerde, M., F. Grosveld, and P. Fraser. 1995. Transcription complex stability and chromatin dynamics in vivo. Nature 377:209-213.
52. Wu, T.-C., and M. Lichten. 1995. Factors that affect the location and frequency of meiosis-induced double-strand breaks in Saccharomyces cerevisiae. Genetics 140:55-66.
53. Xu, L., and N. Kleckner. 1995. Sequence non-specific double-strand breaks and interhomology interactions prior to double-strand break formation at a meiotic recombination hotspot in yeast. EMBO J. 16:5115-5128.