Enzyme polarization of substrates of dihydrofolate reductase by different theoretical methods

Proteins: Structure, Function and Genetics

Volumn 37, Issue 2, 1999, Pages 157-165

  Greatbanks, Stephen P ^a   Gready, Jill E ^a   Limaye, Ajay C ^b   Rendell, Alistair P ^b  

^a Australian National University   (Australia)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

Atomic charges; Density functional methods; Dihydrofolate; Electron density differences; Enzyme mechanism; Folate; NADPH; Quantum chemical methods; Reductase; Substrate polarization

Indexed keywords

DIHYDROFOLATE REDUCTASE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; MATHEMATICAL ANALYSIS; POLARIZATION; PRIORITY JOURNAL; QUANTUM MECHANICS;

EID: 0032693616     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0134(19991101)37:2<157::aid-prot2>3.0.co;2-j     Document Type: Article

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