Antigen-induced TCR-CD3 down-modulation does not require CD3δ or CD3γ cytoplasmic domains, necessary in response to anti-CD3 antibody

International Immunology

Volumn 11, Issue 11, 1999, Pages 1731-1738

  Legendre, Valérie ^a   Guimezanes, Annick ^a   Buferne, Michel ^a   Barad, Marc ^a   Schmitt Verhulst, Anne Marie ^a   Boyer, Claude ^a  

^a INSERM   (France)

Author keywords

Cell cell interactions; Cytotoxic T lymphocyte; Protein kinases; Rodent; TCR

Indexed keywords

CD3 ANTIGEN; CELL RECEPTOR; MONOCLONAL ANTIBODY; PHORBOL ESTER; PROTEIN TYROSINE KINASE INHIBITOR; T LYMPHOCYTE RECEPTOR; TYROSINE;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; CELL CLONE; CELL INTERACTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; ENDOCYTOSIS; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD3; CELL LINE; MICE; PEPTIDES; PROTEIN-TYROSINE KINASES; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0032692379     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/11.11.1731     Document Type: Article

References (46)

1. Klausner, R. D., Lippincott-Schwartz, J. and Bonifacino, J. S. 1990. The T cell antigen receptor: insights into organelle biology. Annu. Rev. Cell Biol. 6:403.
2. Zanders, E. D., Lamb, J. R., Feldmann, M., Green, N. and Beverley, P. C. L. 1983. Tolerance of T-cell clones is associated with membrane antigen changes. Nature 303:625.
3. Valitutti, S., Müller, S., Calla, M., Padovana, E. and Lanzavecchia, A. 1995. Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 375:148.
4. Schönrich, G., Kalinke, U., Momburg, F., Malissen, M., Schmitt-Verhulst, A.-M., Malissen, B., Hämmerling, G. J. and Arnold, B. 1991. Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction. Cell 65:293.
5. Huang, L. and Crispe, I. N. 1993. Superantigen-driven peripheral deletion of T cells. Apoptosis occurs in cells that have lost the alpha/beta T cell receptor. J. Immunol. 151:1844.
6. Valitutti, S., Müller, S., Dessing, M. and Lanzavecchia, A. 1996. Signal extinction and T cell repolarization in T helper cell-antigen presenting cell conjugates. Eur. J. Immunol. 26:2012.
7. Kirchhausen, T., Bonifacino, J. S. and Riezman, H. 1997. Linking cargo to vesicle formation: receptor tail interactions with coat proteins. Curr. Opin. Cell Biol. 9:488.
8. Letourneur, F. and Klausner, R. D. 1992. A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains. Cell 69:1143.
9. Dietrich, J., Kastrup, J., Nielsen, B., Odum, N. and Geisler, C. 1997. Regulation and function of the CD3γDxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro. J. Cell Biol. 138:271.
10. Malissen, B. and Schmitt-Verhulst, A.-M. 1993. Transmembrane signaling through the T cell receptor/CD3 complex. Curr. Opin. Immunol. 5:324.
11. Krangel, M. S. 1987. Endocytosis and recycling of the T3-T cell receptor complex: the role of the T3 phosphorylation. J. Exp. Med. 165:1141.
12. Cantrell, D. A., Davies, A. A. and Crumpton, M. J. 1985. Activators of protein kinase C down-regulate and phosphorylate the T3/T cell antigen receptor complex of human T lymphocytes. Proc. Natl Acad. Sci. USA 82:8158.
13. Boyer, C., Auphan, N., Luton, F., Malburet, J.-M., Barad, M., Bizozzero, J.-P., Reggio, H. and Schmitt-Verhulst, A.-M. 1991. TcR-CD3 complex internalization following activation of a cytolytic T cell clone: evidence for a PKC-independent staurosporine sensitive step. Eur. J. Immunol. 21:1623.
14. Dietrich, J., Hou, X., Wegener, A.-M. K. and Geisler, C. 1994. CD3γ contains a phosphoserine-dependent di-leucine motif involved in down-regulation of the T cell receptor. EMBO J. 13:2156.
15. DeBell, K. E., Conti, A., Alava, M., Hoffman, T. and Bonvini, E. 1992. Microfilament assembly modulates phospholipase C-mediated signal transduction by the TCR-CD3 in murine T helper lymphocytes. J. Immunol. 149:2271.
16. Luton, F., Buferne, M., Davoust, J., Schmitt-Verhulst, A. M. and Boyer, C. 1994. Evidence for protein tyrosine kinase involvement in ligand-induced TCR-CD3 internalization and surface redistribution. J. Immunol. 153:63.
17. Luton, F., Legendre, V., Buferne, M., Gorvel, J.-P., Schmitt-Verhulst, A.-M. and Boyer, C. 1997. Tyrosine and serine protein kinase activities associated with ligand-induced internalized TCR-CD3 complexes. J. Immunol. 158:3140.
18. + T cells. J. Exp. Med. 185:641.
19. Niedergang, F., Hémar, A., Hewitt, C. R. A., Owen, M. J., Dautry-Varsat, A. and Alcover, A. 1995. The Staphylococcus aureus enterotoxin B superantigen induces specific T cell receptor down-regulation by increasing its internalization. J. Biol. Chem. 21:12839.
20. Salio, M., Valitutti, S. and Lanzavecchia, A. 1997. Agonist-induced T cell receptor down-modulation: molecular requirements and dissociation from T cell activation. Eur. J. Immunol. 27:1769.
21. Valitutti, S., Müller, S., Salio, M. and Lanzavecchia, A. 1997. Degradation of T cell receptor (TCR)-CD3-ζ complexes after antigenic stimulation. J. Exp. Med. 185:1859.
22. Luton, F., Buferne, M., Legendre, V., Boyer, C. and Schmitt-Verhulst, A.-M. 1997. Role of CD3γ and CD3δ cytoplasmic domains in cytolytic T lymphocyte functions and TCR-CD3 down-modulation. J. Immunol. 158:4162.
23. Buferne, M., Luton, F., Letourneur, F., Hoeveler, A., Couez, D., Barad, M., Malissen, B., Schmitt-Verhuslt, A.-M. and Boyer, C. 1992. Role of CD3δ in surface expression of the T cell antigen receptor/CD3 complex and in activation for killing analyzed with CD3δ negative cytolytic T lymphocyte variant. J. Immunol. 148:657.
24. Guimezanes, A., Schumacher, T. N. M., Ploegh, H. L. and Schmitt-Verhulst, A.-M. 1992. A viral peptide can mimic an endogenous peptide for allorecognition of a major histocompatibility complex class I product. Eur. J. Immunol. 22:1651.
25. Leo, O., Foo, M., Sachs, D., Samelson, L. and Bluestone, J. 1987. Identification of a monoclonal antibody specific for murine T3. Proc. Natl Acad. Sci. USA 84:1374.
26. Kubo, R. T., Born, W., Kappler, J. W., Marrack, P. and Pigeon, M. 1989. Characterization of a monoclonal antibody which detects all murine ab T cell receptors. J. Immunol. 142:2736.
27. Valitutti, S., Müller, S., Dessing, M. and Lanzavecchia, A. 1996. Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy. J. Exp. Med. 183:1917.
28. + cytotoxic T cell clones. Eur. J. Immunol. 25:3381.
29. Auphan, N., Curnow, J., Guimezanes, A., Langlet, C., Malissen, B., Mellor, A. and Schmitt-Verhulst, A.-M. 1994. The degree of CD8 dependence of cytolytic T cell precursors is determined by the nature of the TCR and influences negative selection in TCR-transgenic mice. Eur. J. Immunol. 24:1572.
30. Viola, A. and Lanzavecchia, A. 1996. T cell activation determined by T cell receptor number and tunable thresholds. Science 273:104.
31. Kishimoto, H., Kubo, R. T., Yorifuji, H., Nakayama, T., Asano, Y. and Tada, T. 1995. Physical dissociation of the TCR-CD3 complex accompanies receptor ligation. J. Exp. Med. 182:1997.
32. Hamer, I., Haft, C. R., Paccaud, J. P., Maeder, C., Taylor, S. and Carpentier, J. L. 1997, Dual role of a dileucine motif in insulin receptor endocytosis. J. Biol. Chem. 272:21685.
33. Felder, S., Miller, K., G., M., Ullrich, A., Schlessinger, J. and Hopkins, C. R. 1990. Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body. Cell 61:623.
34. Waterman, H., Sabanai, I., Geiger, B. and Yarden, Y. 1998. Alternative intracellular routing of ErbB receptors may determine signaling potency. J. Biol. Chem. 273:13819.
35. Goldsmith, M. A. and Weiss, A. 1988. Early signal transduction by the antigen receptor without commitment to T cell activation. Science 240:1029.
36. D'Oro, U., Vacchio, M. S., Weissman, A. M. and Ashwell, J. D. 1997. Activation of the lck tyrosine kinase targets cell surface T cell antigen receptors for lysosomal degradation. Immunity 7:619.
37. Hanke, J. H., Gardner, J. P., Dow, R. L., Changelian, P. S., Brissette, W. H., Weringer, E. J., Pollok, B. A. and Connelly, P. A. 1996. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J. Biol. Chem. 271:695.
38. Berg, N. N. and Ostergaard, H. L. 1997. T cell receptor engagement induces tyrosine phosphorylation of FAK and Pyk2 and their association with Lck. J. Immunol. 159:1753.
39. + T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response. Eur. J. Immunol. 28:716.
40. Marks, M. S., Woodruff, L., Ohno, H. and Bonifacino, J. S. 1996. Protein targeting by tyrosine- and di-leucine-based signals: evidence for distinct saturable components. J. Cell Biol. 135:341.
41. Shiratori, T., Miyatake, S., Ohno, H., Nakaseko, C., Isono, K., Bonifacino, J. S. and Saito, T. 1997. Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP- 2. Immunity 6:583.
42. Wang, X. and Moran, M. F. 1996. Requirement for the adapter protein GRB2 in EGF receptor endocytosis. Science 272:1935.
43. Cenciarelli, C., Wilhelm, K. G., Guo, A. and Weissman, A. M. 1996. T cell antigen ubiquitination is a consequence of receptor-mediated tyrosine kinase activation. J. Biol. Chem. 271:8709.
44. Wulfing, C., Sjaastad, M. D. and Davis, M. M. 1998. Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels. Proc. Natl Acad. Sci. USA 95:6302.
45. Kupfer, A. and Singer, S. J. 1989. Cell biology of cytotoxic and helper T cell functions: immunefluorescence microscopic studies of single cells and cell couples. Annu. Rev. Immunol. 7:309.
46. Dustin, M. L., Miller, J. M., Ranganath, S., Vignali, D. A., Viner, N. J., Nelson, C. A. and Unanue, E. R. 1996. TCP-mediated adhesion of T cell hybridomas to planar bilayers containing purified MHC class II/peptide complexes and receptor shedding during detachment. J. Immunol. 157:2014.