-
1
-
-
0027332995
-
Cloning of a TGFβ type I receptor that forms a heteromeric complex with the TGFβ type II receptor
-
Franzén P, ten Dijke P, Ichijo H, Yamashita H, Schools P, Heldin C-H, et al. Cloning of a TGFβ type I receptor that forms a heteromeric complex with the TGFβ type II receptor. Cell 1993;75:681-92.
-
(1993)
Cell
, vol.75
, pp. 681-692
-
-
Franzén, P.1
Ten Dijke, P.2
Ichijo, H.3
Yamashita, H.4
Schools, P.5
Heldin, C.-H.6
-
2
-
-
0027930903
-
Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-β
-
Yamashita H, ten Dijke P, Franzén P, Miyazono K, Heldin C-H. Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-β. J Biol Chem 1994;269:20172-8.
-
(1994)
J Biol Chem
, vol.269
, pp. 20172-20178
-
-
Yamashita, H.1
Ten Dijke, P.2
Franzén, P.3
Miyazono, K.4
Heldin, C.-H.5
-
3
-
-
0028170226
-
Mechanism of activation of TGFβ receptor
-
Wrana JL, Attisano L, Wieser R, Ventura F, Massagué J. Mechanism of activation of TGFβ receptor. Nature 1994;370:341-7.
-
(1994)
Nature
, vol.370
, pp. 341-347
-
-
Wrana, J.L.1
Attisano, L.2
Wieser, R.3
Ventura, F.4
Massagué, J.5
-
4
-
-
0030300115
-
MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signaling
-
Macías-Silva M, Abdollah S, Hoodless PA, Pirone R, Attisano L, Wrana JL. MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signaling. Cell 1996;87:1215-24.
-
(1996)
Cell
, vol.87
, pp. 1215-1224
-
-
Macías-Silva, M.1
Abdollah, S.2
Hoodless, P.A.3
Pirone, R.4
Attisano, L.5
Wrana, J.L.6
-
5
-
-
16144366751
-
Nomenclature: Vertebrate mediators of TGF-β family signals
-
Derynck R, Gelbart WM, Harland RM, Heldin C-H, Kem SE, Massagué J, et al. Nomenclature: Vertebrate mediators of TGF-β family signals. Cell 1996;87:173.
-
(1996)
Cell
, vol.87
, pp. 173
-
-
Derynck, R.1
Gelbart, W.M.2
Harland, R.M.3
Heldin, C.-H.4
Kem, S.E.5
Massagué, J.6
-
6
-
-
0028940853
-
Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster
-
Sekelski JJ, Newfeld SJ, Raffery LA, Chartoff EH, Gelbart WM. Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 1995;139:1347-58.
-
(1995)
Genetics
, vol.139
, pp. 1347-1358
-
-
Sekelski, J.J.1
Newfeld, S.J.2
Raffery, L.A.3
Chartoff, E.H.4
Gelbart, W.M.5
-
7
-
-
0030058914
-
Caenorhabditis elegans genes sma-2, sma-3 and sma-4 define a conserved family of transforming growth factor β pathway components
-
Savage C, Das P, Finelli AL, Townsend SR, Sun CY, Baird SE, et al. Caenorhabditis elegans genes sma-2, sma-3 and sma-4 define a conserved family of transforming growth factor β pathway components. Proc Natl Acad Sci USA 1996;93:790-4.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 790-794
-
-
Savage, C.1
Das, P.2
Finelli, A.L.3
Townsend, S.R.4
Sun, C.Y.5
Baird, S.E.6
-
8
-
-
0029786212
-
Receptor-associated Mad homologues synergize as effectors of the TGF-β response
-
Zhang Y, Feng X-H, Wu R-Y, Derynck R. Receptor-associated Mad homologues synergize as effectors of the TGF-β response. Nature 1996;383:168-72.
-
(1996)
Nature
, vol.383
, pp. 168-172
-
-
Zhang, Y.1
Feng, X.-H.2
Wu, R.-Y.3
Derynck, R.4
-
9
-
-
0030768644
-
TGF-β receptor-mediated signalling through Smad2, Smad3 and Smad4
-
Nakao A, Imamura T, Souchelnytskyi S, Kawabata M, Ishisaki A, Oeda E, et al. TGF-β receptor-mediated signalling through Smad2, Smad3 and Smad4. EMBO J 1997;16:5353-62.
-
(1997)
EMBO J
, vol.16
, pp. 5353-5362
-
-
Nakao, A.1
Imamura, T.2
Souchelnytskyi, S.3
Kawabata, M.4
Ishisaki, A.5
Oeda, E.6
-
10
-
-
0030613262
-
Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-β signaling
-
Souchelnytskyi S, Tamaki K, Engström U, Wernstedt C, ten Dijke P, Heldin C-H. Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-β signaling. J Biol Chem 1997;272:28107-15.
-
(1997)
J Biol Chem
, vol.272
, pp. 28107-28115
-
-
Souchelnytskyi, S.1
Tamaki, K.2
Engström, U.3
Wernstedt, C.4
Ten Dijke, P.5
Heldin, C.-H.6
-
11
-
-
0030613249
-
TβRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling
-
Abdollah S, Macías-Silva M, Tsukazaki T, Hayashi H, Attisano, L Wrana JL. TβRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling. J Biol Chem 1997;272:27678-85.
-
(1997)
J Biol Chem
, vol.272
, pp. 27678-27685
-
-
Abdollah, S.1
Macías-Silva, M.2
Tsukazaki, T.3
Hayashi, H.4
Attisano, L.5
Wrana, J.L.6
-
12
-
-
0029834067
-
Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways
-
Lagna G, Hata A, Hemmati-Brivanlou A, Massagué J. Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways. Nature 1996;383:832-6.
-
(1996)
Nature
, vol.383
, pp. 832-836
-
-
Lagna, G.1
Hata, A.2
Hemmati-Brivanlou, A.3
Massagué, J.4
-
13
-
-
0029802485
-
A transcriptional partner for MAD proteins in TGF-β signalling
-
Chen X, Rubock MJ, Whitman M. A transcriptional partner for MAD proteins in TGF-β signalling. Nature 1996;383:691-6.
-
(1996)
Nature
, vol.383
, pp. 691-696
-
-
Chen, X.1
Rubock, M.J.2
Whitman, M.3
-
14
-
-
16044369574
-
MADR2 maps to 18q21 and encodes TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
-
Eppert K, Scherer SW, Ozcelik H, Pirone R, Hoodless P, Kim H, et al. MADR2 maps to 18q21 and encodes TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 1996;86:543-52.
-
(1996)
Cell
, vol.86
, pp. 543-552
-
-
Eppert, K.1
Scherer, S.W.2
Ozcelik, H.3
Pirone, R.4
Hoodless, P.5
Kim, H.6
-
15
-
-
0025056930
-
Identification of chromosome 18q gene that is altered in colorectal cancers
-
Fearon ER, Cho KR, Nigro JM, Kern SE, Simons JW, Ruppert JM, et al. Identification of chromosome 18q gene that is altered in colorectal cancers. Science 1990;247:49-56.
-
(1990)
Science
, vol.247
, pp. 49-56
-
-
Fearon, E.R.1
Cho, K.R.2
Nigro, J.M.3
Kern, S.E.4
Simons, J.W.5
Ruppert, J.M.6
-
16
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn SA, Schutte M, Hoque ATMS, Moskaluk CA, da Costa LT, Rozenblum E, et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 1996;271:350-3.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.M.S.3
Moskaluk, C.A.4
Da Costa, L.T.5
Rozenblum, E.6
-
17
-
-
0028340088
-
Point mutations and allelic deletion of tumor suppressor gene DCC in human esophageal squamous cell carcinomas and their relation to metastasis
-
Miyake S, Nagai K, Yoshino K, Oto M, Endo M, Yuasa Y. Point mutations and allelic deletion of tumor suppressor gene DCC in human esophageal squamous cell carcinomas and their relation to metastasis. Cancer Res 1994;54:3007-10.
-
(1994)
Cancer Res
, vol.54
, pp. 3007-3010
-
-
Miyake, S.1
Nagai, K.2
Yoshino, K.3
Oto, M.4
Endo, M.5
Yuasa, Y.6
-
18
-
-
9044243025
-
Homozygous deletion map at 18q21.1 in pancreatic cancer
-
Hahn SA, Hoque ATMS, Moskaluk CA, da Costa LT, Schutte M, Rozenblum E, et al. Homozygous deletion map at 18q21.1 in pancreatic cancer. Cancer Res 1996;56:490-4.
-
(1996)
Cancer Res
, vol.56
, pp. 490-494
-
-
Hahn, S.A.1
Hoque, A.T.M.S.2
Moskaluk, C.A.3
Da Costa, L.T.4
Schutte, M.5
Rozenblum, E.6
-
19
-
-
0029759540
-
Allelic loss and mutational analysis of the DPC4 gene in esophageal adenocarcinoma
-
Barrett MT, Schutte M, Kern SE, Reid BJ. Allelic loss and mutational analysis of the DPC4 gene in esophageal adenocarcinoma. Cancer Res 1996;56:4351-3.
-
(1996)
Cancer Res
, vol.56
, pp. 4351-4353
-
-
Barrett, M.T.1
Schutte, M.2
Kern, S.E.3
Reid, B.J.4
-
20
-
-
15844387270
-
MAD-related genes in the human
-
Riggins GJ, Thiagalingam S, Rozenblum E, Weinstein CL, Kern SE, Hamilton SR, et al. MAD-related genes in the human. Nature Genet 1996;13:347-9.
-
(1996)
Nature Genet
, vol.13
, pp. 347-349
-
-
Riggins, G.J.1
Thiagalingam, S.2
Rozenblum, E.3
Weinstein, C.L.4
Kern, S.E.5
Hamilton, S.R.6
-
21
-
-
0029731630
-
Somatic in vivo alterations of the JV18-1 gene at 18q21 in human lung cancers
-
Uchida K, Nagatake M, Osada H, Yatabe Y, Kondo M, Mitsudomi T, et al. Somatic in vivo alterations of the JV18-1 gene at 18q21 in human lung cancers. Cancer Res 1996;56:5583-5.
-
(1996)
Cancer Res
, vol.56
, pp. 5583-5585
-
-
Uchida, K.1
Nagatake, M.2
Osada, H.3
Yatabe, Y.4
Kondo, M.5
Mitsudomi, T.6
-
22
-
-
0031889595
-
Characterization of the MADH2/Smad2 gene, a human Mad homolog responsible for the transforming growth factor-β and activin signal transduction pathway
-
Takenoshita S, Mogi A, Nagashima M, Yang K, Yagi K, Hanyu A, et al. Characterization of the MADH2/Smad2 gene, a human Mad homolog responsible for the transforming growth factor-β and activin signal transduction pathway. Genomics 1998;48:1-11.
-
(1998)
Genomics
, vol.48
, pp. 1-11
-
-
Takenoshita, S.1
Mogi, A.2
Nagashima, M.3
Yang, K.4
Yagi, K.5
Hanyu, A.6
-
23
-
-
0022361168
-
Growth-promoting effect of gastrin on human gastric carcinoma cell line TMK-1
-
Ochiai A, Yasui W, Tahara E. Growth-promoting effect of gastrin on human gastric carcinoma cell line TMK-1. Jpn J Cancer Res 1985;76:1064-71.
-
(1985)
Jpn J Cancer Res
, vol.76
, pp. 1064-1071
-
-
Ochiai, A.1
Yasui, W.2
Tahara, E.3
-
24
-
-
0025966694
-
Establishment and characterization of human signet ring cell gastric carcinoma cell lines with amplification of the c-myc oncogene
-
Yanagihara K, Seyama T, Tsumuraya M, Kamada N, Yokoro K. Establishment and characterization of human signet ring cell gastric carcinoma cell lines with amplification of the c-myc oncogene. Cancer Res 1991;51:381-6.
-
(1991)
Cancer Res
, vol.51
, pp. 381-386
-
-
Yanagihara, K.1
Seyama, T.2
Tsumuraya, M.3
Kamada, N.4
Yokoro, K.5
-
25
-
-
0025807514
-
Frequent loss of heterozygosity on chromosome 1q, 5q and 17p
-
Sano T, Tsujino T, Yoshida K, Nakayama H, Haruma K, Ito H, et al. Frequent loss of heterozygosity on chromosome 1q, 5q and 17p. Cancer Res 1991;51:2926-31.
-
(1991)
Cancer Res
, vol.51
, pp. 2926-2931
-
-
Sano, T.1
Tsujino, T.2
Yoshida, K.3
Nakayama, H.4
Haruma, K.5
Ito, H.6
-
26
-
-
0031006336
-
MAD-related genes on 18q21.1, Smad2 and Smad4, are altered infrequently in esophageal squamous cell carcinoma
-
Maesawa C, Tamura G, Nishizuka S, Iwaya T, Ogasawara S, Ishida K, et al. MAD-related genes on 18q21.1, Smad2 and Smad4, are altered infrequently in esophageal squamous cell carcinoma. Jpn J Cancer Res 1997;88:340-3.
-
(1997)
Jpn J Cancer Res
, vol.88
, pp. 340-343
-
-
Maesawa, C.1
Tamura, G.2
Nishizuka, S.3
Iwaya, T.4
Ogasawara, S.5
Ishida, K.6
-
27
-
-
14444275781
-
Expression and mutational analysis of the DCC, DPC4 and MADR2/JV18-1 genes in neuroblastoma
-
Kong X-T, Choi SH, Inoue A, Xu F, Chen T, Takita J, et al. Expression and mutational analysis of the DCC, DPC4 and MADR2/JV18-1 genes in neuroblastoma. Cancer Res 1997;57:3772-8.
-
(1997)
Cancer Res
, vol.57
, pp. 3772-3778
-
-
Kong, X.-T.1
Choi, S.H.2
Inoue, A.3
Xu, F.4
Chen, T.5
Takita, J.6
-
28
-
-
0031976330
-
Mutation of the transforming growth factor-β type II receptor gene is rare event in human sporadic gastric carcinomas
-
Shitara Y, Yokozaki H, Yasui W, Takenoshita S, Nagamachi Y, Tahara E. Mutation of the transforming growth factor-β type II receptor gene is rare event in human sporadic gastric carcinomas. Int J Oncol 1998;12:1061-5.
-
(1998)
Int J Oncol
, vol.12
, pp. 1061-1065
-
-
Shitara, Y.1
Yokozaki, H.2
Yasui, W.3
Takenoshita, S.4
Nagamachi, Y.5
Tahara, E.6
-
29
-
-
0031843618
-
Mutation analysis of the Smad2 gene in human colon cancers using genomic DNA and intron primers
-
Takenoshita S, Tani M, Mogi A, Nagashima M, Nagamachi Y, Bennet WP, et al. Mutation analysis of the Smad2 gene in human colon cancers using genomic DNA and intron primers. Carcinogenesis 1998;19:803-7.
-
(1998)
Carcinogenesis
, vol.19
, pp. 803-807
-
-
Takenoshita, S.1
Tani, M.2
Mogi, A.3
Nagashima, M.4
Nagamachi, Y.5
Bennet, W.P.6
-
30
-
-
0028785603
-
Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer
-
Parsons R, Myeroff LL, Liu B, Willson JKV, Markowitz S, Kinzler KW, et al. Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer. Cancer Res 1995;55:5548-50.
-
(1995)
Cancer Res
, vol.55
, pp. 5548-5550
-
-
Parsons, R.1
Myeroff, L.L.2
Liu, B.3
Willson, J.K.V.4
Markowitz, S.5
Kinzler, K.W.6
-
31
-
-
0029066689
-
Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability
-
Markowitz S, Wang J, Myeroff LL, Parsons R, Sun L, Lutterbaugh J, et al. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science 1995;268:1336-8.
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
Wang, J.2
Myeroff, L.L.3
Parsons, R.4
Sun, L.5
Lutterbaugh, J.6
-
32
-
-
0028785602
-
A Transforming growth factor β receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability
-
Myeroff LL, Parsons R, Kim S-J, Hedrick L, Cho KR, Orth K, et al. A Transforming growth factor β receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability. Cancer Res 1995;55:5545-7.
-
(1995)
Cancer Res
, vol.55
, pp. 5545-5547
-
-
Myeroff, L.L.1
Parsons, R.2
Kim, S.-J.3
Hedrick, L.4
Cho, K.R.5
Orth, K.6
-
33
-
-
0030849060
-
Mutation analysis of the transforming growth factor-β type II receptor in human cell lines resistant to growth inhibition by transforming growth factor-β
-
Vincent F, Nagashima M, Takenoshita S, Khan MA, Gemma A, Hagiwara K, et al. Mutation analysis of the transforming growth factor-β type II receptor in human cell lines resistant to growth inhibition by transforming growth factor-β. Oncogene 1997;15:117-22.
-
(1997)
Oncogene
, vol.15
, pp. 117-122
-
-
Vincent, F.1
Nagashima, M.2
Takenoshita, S.3
Khan, M.A.4
Gemma, A.5
Hagiwara, K.6
-
34
-
-
0029114477
-
Missense mutations of the transforming growth factor β type II receptor in human head and neck squamous carcinoma cells
-
Garrigue-Antar L, Muñoz-Antonia T, Antonia SJ, Gesmonde J, Vellucci VF. Reiss M. Missense mutations of the transforming growth factor β type II receptor in human head and neck squamous carcinoma cells. Cancer Res 1995;55:3982-7.
-
(1995)
Cancer Res
, vol.55
, pp. 3982-3987
-
-
Garrigue-Antar, L.1
Muñoz-Antonia, T.2
Antonia, S.J.3
Gesmonde, J.4
Vellucci, V.F.5
Reiss, M.6
-
35
-
-
0030048263
-
Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β1 in human prostate cancer cells
-
Kim IY, Ahn H-J, Zelner DJ, Shaw JW, Sensibar JA, Kim J-H, et al. Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β1 in human prostate cancer cells. Cancer Res 1996;56:44-8.
-
(1996)
Cancer Res
, vol.56
, pp. 44-48
-
-
Kim, I.Y.1
Ahn, H.-J.2
Zelner, D.J.3
Shaw, J.W.4
Sensibar, J.A.5
Kim, J.-H.6
-
36
-
-
0030775491
-
Inactivation of Smad4 in gastric carcinomas
-
Powell SM, Harper JC, Hamilton SR, Robinson CR, Cummings OW. Inactivation of Smad4 in gastric carcinomas. Cancer Res 1997;57:4221-4.
-
(1997)
Cancer Res
, vol.57
, pp. 4221-4224
-
-
Powell, S.M.1
Harper, J.C.2
Hamilton, S.R.3
Robinson, C.R.4
Cummings, O.W.5
-
37
-
-
0032498328
-
Genetic structure of the human Smad3 gene and its infrequent alterations in colorectal cancers
-
Arai T, Akiyama Y, Okabe S, Ando M, Endo M, Yuasa Y. Genetic structure of the human Smad3 gene and its infrequent alterations in colorectal cancers. Cancer Lett 1998;122:157-63.
-
(1998)
Cancer Lett
, vol.122
, pp. 157-163
-
-
Arai, T.1
Akiyama, Y.2
Okabe, S.3
Ando, M.4
Endo, M.5
Yuasa, Y.6
-
38
-
-
0031587828
-
The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling
-
Hayashi H, Abdollah S, Qiu Y; Cai J, Xu Y-Y, Grinnell BW, et al. The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling. Cell 1997;89:1165-73.
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qiu, Y.3
Cai, J.4
Xu, Y.-Y.5
Grinnell, B.W.6
-
39
-
-
0030611757
-
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
-
Nakao A, Afrakhte M, Morén A, Nakayama T, Christian JL, Heuchel R, et al. Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling. Nature 1997;389:631-5.
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Morén, A.3
Nakayama, T.4
Christian, J.L.5
Heuchel, R.6
-
40
-
-
0030765945
-
Smad6 inhibits signalling by the TGF-β superfamily
-
Imamura T, Takase M, Nishihara A, Oeda E, Hanai J, Kawabata M, et al. Smad6 inhibits signalling by the TGF-β superfamily. Nature 1997;389:622-6.
-
(1997)
Nature
, vol.389
, pp. 622-626
-
-
Imamura, T.1
Takase, M.2
Nishihara, A.3
Oeda, E.4
Hanai, J.5
Kawabata, M.6
|