The development of awareness of the carcinogenic hazard of inhaled iron

Oncology Research

Volumn 11, Issue 3, 1999, Pages 109-113

  Weinberg, Eugene D ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

Asbestos; Inhaled iron withholding; Lung cancer; Tobacco smoking

Indexed keywords

ASBESTOS; CARCINOGEN; IRON;

ANIMAL; DISEASE MODEL; EXPOSURE; HUMAN; INDOOR AIR POLLUTION; LUNG TUMOR; OCCUPATIONAL EXPOSURE; REVIEW; SMOKING;

ANIMALS; ASBESTOS; CARCINOGENS; DISEASE MODELS, ANIMAL; HUMANS; INHALATION EXPOSURE; IRON; LUNG NEOPLASMS; OCCUPATIONAL EXPOSURE; SMOKING; TOBACCO SMOKE POLLUTION;

EID: 0032613201     PISSN: 09650407     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Weinberg, E. D. The role of iron in cancer. Eur. J. Cancer Prev. 5:19-36; 1996.
2. Dreyfus, J. R. Lungencarcinom bei Geschwistern nach Inhalation von eisenoxydhaltigem Staub in der Jugend. Zeit. Klin. Med. 130: 256-260; 1936.
3. Boyd, J. T.; Doll, R.; Faulds, J. S.; Leiper, J. Cancer of the lung in iron ore (haematite) miners. Br. J. Ind. Med. 27:275-280; 1970.
4. Icso, J.; Szollosova, M.; Sorahan, T. Lung cancer among iron ore miners in east Slovakia: A case control study. Occup. Environ. Med. 51:642-643; 1994.
5. Antoine, D.; Braun, P.; Cervoni, P.; Schwartz, P.; Lamy, P. Le cancer bronique des mineurs de fer de Lorraine peut-il etre considère comme une maladie professionelle? Rev. Fr. Mal. Respir. 7: 63-65; 1979.
6. Tumer, H. M.; Grace, H. G. An investigation into cancer mortality among males in certain Sheffield trades. J. Hyg. 38:90-103; 1938.
7. Blot, W. J.; Brown, L. M.; Pottern, L. M.; Stone, B. J.; Fraumeni, J. F., Jr. Lung cancer among steel workers. Am. J. Epidemiol. 117:706-715; 1983.
8. Sherson, D.; Svane, O.; Lynge, E. Cancer incidence among foundry workers in Denmark. Arch. Environ. Health 46:75-81; 1991.
9. Gibson, E. S.; Martin, R. H.; Lockington, J. N. Lung cancer mortality in a steel foundry. J. Occup. Med. 19:807-812; 1977.
10. Guest, L. The endogenous iron content, by Mossbauer spectroscopy, of human lungs-II. Lungs from various occupational groups. Ann. Occup. Hyg. 21:151-157; 1978.
11. Corhay, J. L.; Weber, G.; Bury, Th.; Mariz, S.; Roelandts, I.; Radermecker, M. F. Iron content in human alveolar macrophages. Eur. Respir. J. 5:804-809; 1992.
12. Campbell, J. A. Effects of precipitated silica and of iron oxide on the incidence of primary lung tumors in mice. Br. Med. J. 2:275-280; 1940.
13. Pott, F.; Ziem, U.; Reiffer, F-J.; Huth, F.; Ernst, H.; Mohr, U. Carcinogenicity studies on fibres, metal compounds, and some other dust in rats. Exp. Pathol. 32:129-152; 1987.
14. Steinhoff, D.; Mohr, U.; Hahnemann, S. Carcinogenesis studies with iron oxides. Exp. Pathol. 43:189-194; 1991.
15. Castranova, V.; Vallyathan, V.; Ramsey, D. M.; McLaurin, J. L.; Pack, D.; Leonard, S.; Barger, M. W.; Ma, J. Y. C.; Dalal, N. S.; Teass, A. Augmentation of pulmonary reactions to quartz inhalation by trace amounts of iron-containing particles. Environ. Health Perspect. 105(Suppl. 5):1319-1324; 1997.
16. Ghio, A. J.; Kennedy, T. P.; Whorton, A. R.; Crumbliss, A. L.; Hatch, G. E.; Holdal, J. R. Role of surface complexed iron in oxidant generation and lung inflammation induced by silicates. Am. J. Physiol. 263:L511-L518; 1992.
17. Goodglick, L. A.; Kane, A. B. Role of reactive oxygen metabolites in crocidolite asbestos toxicity to mouse macrophages. Cancer Res. 46:5558-5566; 1986.
18. Keeling, B.; Li, K. Y.; Churg, A. Iron enhances uptake of mineral particles and increases lipid peroxidation in trachéal epithelial cells. Am. J. Respir. Cell Mol. Biol. 10:683-688; 1994.
19. Stokinger, H. E. A review of world literature finds iron oxides noncarcinogenic. Am. Ind. Hyg. Assoc. J. 45:127-133; 1984.
20. Hardy, J. A.; Aust, A. E. Iron in asbestos chemistry and carcinogenicity. Chem. Rev. 95:97-118; 1995.
21. Fubini, B.; Mollo, L. Role of iron in the reactivity of mineral fibers. Toxicol. Lett. 83:951-960; 1995.
22. Churg, A. Chrysotile, tremolite, and malignant mesothelioma in man. Chest 93:621-628; 1988.
23. Pisani, R. J.; Colby, T. V.; Williams, D. E. Malignant mesothelioma of the pleura. Mayo Clin. Proc. 63:1234-1244; 1988.
24. Garcia, J. G. N.; Dodson, R. F.; Callahan, K. S. Effect of environmental participates on cultured human and bovine endothelium. Lab. Invest. 61:53-61; 1989.
25. Lund, L. G.; Aust, A. E. Iron mobilization from crocidolite asbestos greatly enhances crocidolite-dependent formation of DNA single-strand breaks in phi X174 RFI DNA. Carcinogenesis 13:637-642; 1992.
26. Chao, C-C; Lund, L. G.; Zinn, K. R.; Aust, A. E. Iron mobilization from crocidolite asbestos by human lung carcinoma cells. Arch. Biochem. Biophys. 314:384-391; 1994.
27. Eborn, S. K.; Aust, A. E. Effect of iron acquisition on induction of DNA single-strand breaks by erionite, a carcinogenic mineral fiber. Arch. Biochem. Biophys. 316:507-514; 1995.
28. + Chinese hamster cells. Cancer Res. 58:1144-1148; 1998.
29. Smith, K. R.; Aust, A. E. Mobilization of iron from urban particulates leads to the generation of reactive oxygen species in vitro and induction of ferritin synthesis in human lung epithelial cells. Chem. Res. Toxicol. 10:828-834; 1997.
30. Smith, K. R.; Veranth, J. M.; Lighty, J. S.; Aust, A. E. Mobilization of iron from coal fly ash was dependent upon the particle size and the source of coal. Chem. Res. Toxicol. 11:1494-1500; 1998.
31. Carbone, D. Smoking and cancer. Am. J. Med. 93(Suppl. 1A): 13S-17S; 1992.
32. Goto, F.; Yoshihara, T.; Saiki, H. Iron accumulation in tobacco plants expressing soyabean ferritin gene. Transgenic Res. 7:173-180; 1998.
33. Thompson, A. B.; Bohling, T.; Heires, A.; Linder, J.; Rcnnard, S. I. Lower respiratory tract iron burden is increased in association with cigarette smoking. J. Lab. Clin. Med. 117:493-499; 1991.
34. McGowan, S. E.; Murray, J. J.; Parrish, M. G. Iron binding, internalization, and fate in human alveolar macrophages. J. Lab. Clin. Med. 108:587-595; 1986.
35. Wesselius, L. J.; Flowers, C. H.; Skikne, B. S. Alveolar macrophage content of isoferritins and transferrin. Am. Rev. Respir. Dis. 145:311-316; 1992.
36. Green, R.; Esparza, I.; Schreiber, R. Iron inhibits the non-specific tumoricidal activity of macrophages. Ann. NY Acad. Sci. 526: 301-309; 1988.
37. McGowan, S. E.; Henley, S. A. Iron and ferritin contents and distribution in human alveolar macrophages. J. Lab. Clin. Med. 111:611-617; 1988.
38. Wesselius, L. J.; Nelson, M. E.; Skikne, B. S. Increased release of ferrilin and iron by iron-loaded alveolar macrophages in cigarette smoking. Am. J. Respir. Crit. Care Med. 150:690-695; 1994.
39. Lapenna, D.; de Gioia, S.; Mezzetti, A.; Ciofani, G.; Consoli, A.; Marzio, L.; Cuccurullo, F. Cigarette smoke, ferritin, and lipid peroxidation. Am. J. Respir. Crit. Care Med. 151:431-435; 1995.
40. Nelson, M. E.; O'Brien-Ladner, A. R.; Wesselius, L. J. Regional variation in iron and iron-binding proteins within the lungs of smokers. Am. J. Respir. Crit. Care Med. 153:1353-1358; 1996.
41. Breuer, W.; Greenberg, E.; Cabantchik, Z. 1. Newly delivered transferrin iron and oxidative cell injury. FEBS Lett. 40:213-219; 1997.
42. Wesselius, L. J.; Williams, W. L.; Bailey, K.; Vamos, S.; O'Brien-Ladner, A. R.; Wiegmann, T. Iron uptake promotes hyperoxic injury to alveolar macrophages. Am. J. Respir. Crit. Care Med. 159: 100-106; 1999
43. Fang, R.; Aust, A. E. Induction of ferritin synthesis in human lung epithelial cells treated with crocidolite asbestos. Arch. Biochem. Biophys. 340:369-375; 1997.
44. Weinberg, E. D. Monitor iron loading in disease surveillance. Emerging Infec. Dis. 5:346-352; 1999.
45. Pacht, E. R.; Davis, W. B. Role of transferrin and ccruloplasmin in antioxidant activity of lung epithelial lining fluid. J. Appl. Physiol. 64:2092-2099; 1988.
46. Wesselius, L. J.; Smimov, I. M.; Nelson, M. E.; O'Brien-Ladner, A. R.; Flowers, C. H.; Skikne, B. S. Alveolar macrophages accumulate iron and ferritin after in vivo exposure to iron or tungsten dusts. J. Lab. Clin. Med. 127:401-409; 1996.
47. Lay, J. C.; Bennett, W. D.; Kim, C. S.; Devlin, R. B.; Bromberg, P. A. Retention and intraccllular distribution of instilled iron oxide particles in human alveolar macrophages. Am. J. Respir. Cell Mol. Biol. 18:687-695; 1998.
48. Ghio, A. J.; Jaskot, R. H.; Hatch, G. E. Lung injury after silica instillation is associated with an accumulation of iron in rats. Am. J. Physiol. 267:L686-L692; 1994.
49. Kamp, D. W.; Israbian, V. A.; Yeldandi, A. V.; Panos, R. J.; Graceffa, P.; Weitzman, S. A. Phytic acid, an iron chelator, attenuates pulmonary inflammation and fibrosis in rats after intratracheal instillation of asbestos. Toxicol. Pathol. 23:689-695; 1995.
50. LaLonde, C.; Ikegami, K.; Demling, R. Aerosolized deferoxamine prevents lung and systemic injury caused by smoke inhalation. J. Appl. Physiol. 77:2057-2064; 1994.
51. Mateos, F.; Gonzalez, C.; Dominguez, C.; Losa, J-E.; Jiminez, A.; Perez-Arellano, J-L. Elevated non-transfcrrin bound iron in the lungs of patients with Pneumocystis carinii pneumonia. J. Infect. 38:18-21; 1999.
52. Weinberg, E. D. Host range and tissue colonization of pathogens: Role of iron acquisition. Proc. Int. Soc. Microb. Ecol. (in press).
53. Frcidank, H. M.; Billing, H. Influence of iron restriction on the growth of Chlamydia pneumoniae TWAR and Chlamydia irachomatis. Clin. Microbiol. Infect. 3(Suppl. 2):193; 1997.