Binding of phenol to R6 insulin hexamers

Biopolymers - Peptide Science Section

Volumn 51, Issue 2, 1999, Pages 165-172

  Berchtold, Harald ^a   Hilgenfeld, Rolf ^b  

^a SANOFI   (France)

^b FRITZ LIPMANN INSTITUTE   (Germany)

Author keywords

Allosteric transformation; HOE 901; Insulin; Phenol; Protraction of activity; R6 insulin

Indexed keywords

CHEMICAL BONDS; CONFORMATIONS; CRYSTAL STRUCTURE; MOLECULAR STRUCTURE; PHENOLS;

ALLOSTERIC TRANSFORMATION;

INSULIN;

INSULIN DERIVATIVE; INSULIN GLARGINE; PHENOL; PRESERVATIVE; DRUG; DRUG DERIVATIVE; INSULIN;

ALLOSTERISM; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG CONFORMATION; DRUG FORMULATION; DRUG STRUCTURE; PROTEIN CONFORMATION; X RAY ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; PROTEIN BINDING; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; INSULIN; MODELS, MOLECULAR; PHARMACEUTICAL PREPARATIONS; PHENOL; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 0032613186     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0282(1999)51:2<165::AID-BIP6>3.0.CO;2-X     Document Type: Article

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