Light dose fractionation to enhance photodynamic therapy using 5-aminolevulinic acid in the normal rat colon

Photochemistry and Photobiology

Volumn 69, Issue 1, 1999, Pages 71-76

  Curnow, Alison ^a,b   McIlroy, Brian W ^a   Postle Hacon, Matthew J ^a   MacRobert, Alexander J ^a   Bown, Stephen G ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b National Medical Laser Centre   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

AMINOLEVULINIC ACID; PHOTOSENSITIZING AGENT;

ANIMAL; ARTICLE; BIOLOGY; COLON; DRUG EFFECT; FEMALE; METHODOLOGY; NECROSIS; PATHOLOGY; PHOTOCHEMOTHERAPY; RADIATION EXPOSURE; RAT; WISTAR RAT;

AMINOLEVULINIC ACID; ANIMALS; COLON; FEMALE; NECROSIS; PHOTOBIOLOGY; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; RATS; RATS, WISTAR;

EID: 0032601444     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.1999.tb05308.x     Document Type: Article

References (32)

1. Henderson, B. W. and T. J. Dougherty (1992) How does photodynamic therapy work? Photochem. and Photobiol. 55, 145-157.
2. Bonnett, R. (1995) Photosensitizers of the porphyrin and phthalocyanine series for photodynamic therapy. Chem. Soc. Rev. 24, 19-33.
3. Stryer, L. (1988) Biochemistry, 3rd ed., pp. 594-597. W. H. Freeman and Company, New York.
4. Kennedy, J. C. and R. H. Pottier (1992) Endogenous protoporphyrin IX, a clinical useful photosensitizer for photodynamic therapy. J. Photochem. Photobiol. B Biol. 14, 275-292.
5. Bedwell, J., A. J. MacRobert, D. Philips and S. G. Bown (1992) Fluorescence distribution and photodynamic effect of ALA-induced PPIX in the DMH rat colonic tumour model. Br. J. Cancer 65, 818-824.
6. Regula, J., A. J. MacRobert, A. Gorchein, G. A. Buonaccorsi, S. M. Thorpe, G. M. Spencer, A. R. W. Hatfield and S. G. Bown (1995) Photosensitisation and photodynamic therapy of oesophageal, duodenal and colorectal tumours using 5-aminolevulinic acid induced protoporphyrin IX. Gut 36, 67-75.
7. Barr, H., N. A. Shepherd, A. Dix, D. J. H. Roberts, W. C. Tan and N. Krasner (1996) Eradication of high-grade dysplasia in columnar-lined (Barrettís) oesophagus by photodynamic therapy with endogenously generated protoporphyrin IX. Lancet 348, 584-585.
8. Gossner, L., M. Stolte, R. Sroka, K. Rick, A. May, E. G. Hahn and C. Ell (1998) Photodynamic ablation of high-grade dysplasia and early cancer in Barrettís esophagus by means of 5-aminolaevulinic acid. Gastroenterology 114, 448-455.
9. Loh, C. S., D. Vernon, A. J. MacRobert, J. Bedwell, S. G. Bown and S. B. Brown (1993) Endogenous porphyrin distribution induced by 5-aminolevulinic acid in the tissue layers of the gastrointestinal tract. J. Photochem. Photobiol. B Biol. 20, 47-54.
10. Overholt, B. F. and M. Panjehpour (1997) Photodynamic therapy for Barrettís oesophagus. Gastrointest. Endosc. Clin. North Am. 7, 202-220.
11. Marijnissen, J. P. A. and W. M. Star (1987) Quantitative light dosimetry in vitro and in vivo. Lasers Med. Sci. 2, 235-242.
12. Messmann, H., P. Mlkvy, G. Buonaccorsi, C. L. Davies, A. J. MacRobert and S. G. Bown (1995) Enhancement of photodynamic therapy with 5-aminolevulinic acid-induced porphyrin photosensitisation in normal rat colon by threshold and light fractionation studies. Br. J. Cancer 72, 589-594.
13. Robinson, D. J., H. S. de Bruijn, N. van der Veen, M. R. Stringer, S. B. Brown and W. M. Star (1998) Fluorescence photobleaching of ALA-induced protoporphyrin IX during photodynamic therapy of normal hairless mouse skin: the effect of light dose and irradiance and the resulting biological effect. Photochem. Photobiol. 67, 140-149.
14. Peng, Q., J. Moan, T. Warloe, I. Vladimir, H. B. Steen, A. Bjorseth and J. M. Nesland (1996) Build-up of esterified aminolevulinic-acid-derivative-induced porphyrin fluorescence in normal mouse skin. J. Photochem. Photobiol. B Biol. 34, 95-96.
15. Curnow, A., B. W. McIlroy, M. J. Postle-Hacon, J. B. Porter, A. J. MacRobert and S. G. Bown (1998) Enhancement of 5-aminolevulinic acid induced photodynamic therapy in normal rat colon using hydroxpyridinone iron chelating agents. Br. J. Cancer. 78, 1113-1118.
16. Bourletias, L., P. Lenz and J. Margonari (1994) Characteristics of PDT performed very shortly after sensitizer injection. J. Phys. IV 4, C4-241-C4-244.
17. Pe, M. B., H. Ikeda and T. Inokuchi (1994) Tumour destruction and proliferation kinetics following periodic, low power light, hemeatoporphyrin oligomers mediated photodynamic therapy in the mouse tongue. Oral Oncol. Eur. J. Cancer 30, 174-178.
18. Anholt, H. and J. Moan (1991) Fractionated treatment of CaD2 tumours in mice sensitized with aluminium phthalocyanine tetrasulfonate. Cancer Lett. 61, 263-267.
19. Muller, S., H. Walt, D. Dolber-Girdziunaite, D. Fiedler and U. Haller (1998) Enhanced photodynamic effects using fractionated laser light. J. Photochem. Photobiol. B Biol. 42, 67-70.
20. Mlkvy, P., H. Messmann, M. Pauer, J. C. M. Stewart, C. E. Millson, A. J. MacRobert and S. G. Bown (1996) Distribution and photodynamic effects of meso-tetrahydroxyphenylchlorin (mTHPc) in the pancreas and adjacent tissues in the Syrian golden hamster. Br. J. Cancer 73, 1473-1479.
21. van der Veen, N., H. L. L. M. van Leengoed and W. M. Star (1994) In vivo fluorescence kinetics and photodynamic therapy using 5-aminolevulinic acid-induced porphyrin: increased damage after multiple irradiations. Br. J. Cancer 70, 867-872.
22. Hua, Z., S. L. Gibson, T. H. Foster and R. Hilf (1995) Effectiveness of δ-aminolevulinic acid-induced protoporphyrin as a photosensitizer for photodynamic therapy in vivo. Cancer Res. 55, 1723-1731.
23. Iinuma, S., G. Wagnieres, K. T. Schomacker, M. Bamberg and T. Hassan (1995) The importance of fluence rate in photodynamic therapy with ALA-induced PPIX and BPD-MA in a rat bladder tumor model. SPIE 2392, 136-140.
24. Barr, H., C. J. Tralau, A. J. MacRobert, N. Krasner, P. B. Boulos, C. G. Clark and S. G. Bown (1987) Photodynamic therapy in the normal rat colon with phthalocyanine sensitisation. Br. J. Cancer 56, 111-118.
25. Dietel, W., C. Fritsch, R. H. Pottier and R. Wendenburg (1997) 5-Aminolevulinic-acid-induced formation of different porphyrins and their photomodifications. Lasers Med. Sci. 12, 226-236.
26. Sailer, R., W. S. L. Strauss, K. Konig, A. Ruck and R. Steiner (1997) Correlation between porphyrin biosynthesis and photodynamic inactivation of Pseudomonas aeruginosa after incubation with 5-aminolevulinic acid. J. Photochem. Photobiol. B Biol. 39, 236-242.
27. van Geel, I. P. J., H. Oppelaar, J. P. A. Marijnissen and F. A. Stewart (1996) Influence of fractionation and fluence rate in photodynamic therapy with photofrin or mTHPc. Radiat. Res. 145, 602-609.
28. Foster, T. H., R. S. Murant, R. G. Bryant, R. S. Knox, S. L. Gibson and R. Hilf (1991) Oxygen consumption and diffusion effects in photodynamic therapy. Radiat. Res. 126, 296-303.
29. Leveckis, J., N. J. Brown and M. W. R. Reed (1995) The effect of aminolevulinic acid-induced, protoporphyrin IX-mediated photodynamic therapy on the cremaster muscle microcirculation in vivo. Br. J. Cancer 72, 1113-1119.
30. Roberts, D. J. H., F. Cairnduff, I. Driver, B. Dixon and S. B. Brown (1994) Tumour vascular shutdown following photodynamic therapy based on polyhaematoporphyrin or 5-aminolevulinic acid. Int. J. Oncol. 5, 763-768.
31. McIlroy, B. W., A. Curnow, G. Buonaccorsi, M. A. Scott, S. G. Bown and A. J. MacRobert (1998) Spatial measurement of oxygen levels during photodynamic therapy using time-resolved optical spectroscopy. J. Photochem. Photobiol. B Biol. 43, 47-55.
32. McCord, J. M. (1987) Oxygen-derived radicals: a link between reperfusion injury and inflammation. Fed. Proc. 46, 2402-2405.