Association of the ICAM:1(KILIFI) mutation with protection against severe malaria in lambarene, gabon

American Journal of Tropical Medicine and Hygiene

Volumn 61, Issue 5, 1999, Pages 776-779

  Kun, Jürgen F J ^a   Klabunde, Jens ^a   Lell, Bertrand ^a   Luckner, Doris ^a   Alpers, Michael ^c   May, Jürgen ^b   Meyer, Christian ^b   Kremsner, Peter G ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA; INTERCELLULAR ADHESION MOLECULE 1; ANTIINFECTIVE AGENT; ANTIMALARIAL AGENT; CLINDAMYCIN; ENDODEOXYRIBONUCLEASE NLAIII; FANSIDAR; PRIMER DNA; PYRIMETHAMINE; QUININE; SULFADOXINE; SULFADOXINE-PYRIMETHAMINE; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE;

ARTICLE; CELL ADHESION; CHILD; DISEASE PREDISPOSITION; DNA SEQUENCE; ERYTHROCYTE; GABON; GENE MUTATION; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; AGAR GEL ELECTROPHORESIS; ANIMAL; CASE CONTROL STUDY; CHEMISTRY; DRUG COMBINATION; FEMALE; GENETICS; IMMUNOLOGY; MALARIA FALCIPARUM; MALE; NIGERIA; PAPUA NEW GUINEA; PARASITEMIA; PATHOGENICITY; POINT MUTATION; THAILAND; VIRULENCE;

PLASMODIUM FALCIPARUM; PROTOZOA; RHINOVIRUS;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMALARIALS; CASE-CONTROL STUDIES; CHILD; CLINDAMYCIN; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA; DNA PRIMERS; DRUG COMBINATIONS; ELECTROPHORESIS, AGAR GEL; FEMALE; GABON; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALARIA, FALCIPARUM; MALE; NIGERIA; PAPUA NEW GUINEA; PARASITEMIA; PLASMODIUM FALCIPARUM; POINT MUTATION; POLYMERASE CHAIN REACTION; PYRIMETHAMINE; QUININE; SULFADOXINE; THAILAND; VIRULENCE;

EID: 0032590033     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.1999.61.776     Document Type: Article

References (21)

1. Greenwood BM, Marsh K, Snow RW, 1991. Why do some African children develop severe malaria? Parasitol Today 7: 277-281.
2. Deitsch KW, Wellems TE, 1996. Membrane modifications in erythrocytes parasitized by Plasmodium falciparum. Mol Biochem Parasitol 76: 1-10.
3. Turner GD, Morrison H, Jones M, Davis TM, Looareesuwan S, Buley ID, Gatter KC, Newbold CI, Pukritayakamee S, Nagachinta B, White NJ, Berendt AR, 1994. An immunohistochemical study of the pathology of fatal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration. Am J Pathol 145: 1057-1069.
4. Newbold C, Warn P, Black G, Berendt A, Craig A, Snow B, Msobo M, Peshu N, Marsh K, 1997. Receptor-specific adhesion and clinical disease in Plasmodium falciparum. Am J Trop Med Hyg 57: 389-398.
5. Berendt AR, McDowall A, Craig AG, Bates PA, Sternberg MJ, Marsh K, Newbold CI, Hogg N, 1992. The binding site on ICAM-1 for Plasmodium falciparum-infected erythrocytes overlaps, but is distinct from, the LFA-1-binding site. Cell 68: 71-81.
6. Ockenhouse CF, Betageri R, Springer TA, Staunton DE, 1992. Plasmodium falciparum-infected erythrocytes bind ICAM-1 at a site distinct from LFA-1, Mac-1, and human rhinovirus. Cell 68: 63-69.
7. Zimmerman PA, Wieseman M, Spalding T, Boatin BA, Nutman TB, 1998. A new intercellular adhesion molecule-1 allele identified in West Africans is prevalent in African-Americans in contrast to other North American racial groups. Tissue Antigens 50: 654-656.
8. Fernandez-Reyes D, Craig AG, Kyes SA, Peshu N, Snow RW, Berendt AR, Marsh K, Newbold CI, 1997. A high frequency African coding polymorphism in the N-terminal domain of ICAM-1 predisposing to cerebral malaria in Kenya. Hum Mol Genet 6: 1357-1360.
9. Warrell DA, Molyneux ME, Beales PF, 1990. Severe and complicated malaria. Trans R Soc Trop Med Hyg 84: 1-65.
10. Kremsner PG, Radloff P, Metzger W, Wildling E, Mordmüller B, Philipps J, Jenne L, Nkeyi M, Prada J, Bienzle U, Graninger W, 1995. Quinine plus clindamycin improves chemotherapy of severe malaria in children. Antimicrob Agents Chemother 39: 1603-1605.
11. Schmidt-Ott R, Luckner D, Lehman LG, Lell B, Matousek P, Greve B, Kremsner PG, 1997. Pyrimethamine/sulfadoxine for treating uncomplicated Plasmodium falciparum malaria in young children in Gabon. Trans R Soc Trop Med Hyg 91: 578-579.
12. Kremsner PG, Zotter GM, Feldmeier H, Graninger W, Rocha RM, Wiedermann G, 1988. A comparative trial of three regimens for treating uncomplicated falciparum malaria in Acre, Brazil. J Infect Dis 158: 1368-1371.
13. Metzger WG, Mordmüller BG, Kremsner PG, 1995. Malaria pigment in leucocytes. Trans R Soc Trop Med Hyg 89: 637-638.
14. Saiki RK, Gelfand DH, Stoffel S, Scharf SJ, Higuchi R, Horn GT, Mullis KB, Erlich HA, 1988. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239: 487-491.
15. Sambrook J, Fritsch EF, Maniatis T, 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
16. Bellamy R, Kwiatkowski D, Hill AVS, 1998. Absence of an association between intercellular adhesion molecule 1, complement receptor 1 and interleukin 1 receptor antagonist gene polymorphisms and severe malaria in a West African population. Trans R Soc Trop Med Hyg 92: 312-316.
17. Kun JFJ, Mordmüller B, Lell B, Lehman LG, Luckner D, Kremsner PG, 1998. Polymorphism in the promoter region of the inducible nitric oxide synthase gene and protection against malaria. Lancet 351: 265-266.
18. Kun JFJ, Schmidt-Ott R, Lehman LG, Lell B, Luckner D, Greve B, Matousek P, Kremsner PG, 1998. Merozoite surface antigen 1 and 2 genotyping and resetting of Plasmodium falciparum in severe versus mild malaria in Lambaréné, Gabon. Trans R Soc Trop Med Hyg 92: 110-114.
19. Lell B, May J, Schmidt-Ott RJ, Lehman LG, Luckner D, Greve B, Matouse Schmid D, Merbich K, Mockenhaupt FP, Meyer CG, Bienzle U, Kremsner PG, 1999. The role of red blood cell polymorphisms in resistance and susceptibility to malaria. Clin Infect Dis 28: 794-799.
20. Engelbrecht F, Felger I, Genton B, Alpers M, Beck HP, 1995. Plasmodium falciparum: malaria morbidity is associated with specific merozoite surface antigen 2 genotypes. Exp Parasitol 81: 90-96.
21. Robert F, Ntoumi F, Angel G, Candito D, Rogier C, Fandeur T, Sarthou JL, Mercereau-Puijalon O, 1996. Extensive genetic diversity of Plasmodium falciparum isolates collected from patients with severe malaria in Dakar, Senegal. Trans R Soc Trop Med Hyg 90: 704-711.