Absence of an association between intercellular adhesion molecule 1, complement receptor 1 and interleukin 1 receptor antagonist gene polymorphisms and severe malaria in a West African population

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 92, Issue 3, 1998, Pages 312-316

  Bellamy, Richard ^a   Kwiatkowski, Dominic ^b,c   Hill, Adrian V S ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

Complement receptor 1 gene; Gene polymorphisms; Intercellular adhesion molecule 1 gene; Interleukin 1 receptor antagonist gene; Malaria; Pathogenesis; Plasmodium falciparum; The Gambia

Indexed keywords

COMPLEMENT COMPONENT C3B RECEPTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ANEMIA; ARTICLE; BRAIN MALARIA; CHILD; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; DNA POLYMORPHISM; GAMBIA; GENETIC SUSCEPTIBILITY; HOST SUSCEPTIBILITY; HUMAN; KENYA; MAJOR CLINICAL STUDY; MALARIA; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 0031832778     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(98)91026-4     Document Type: Article

References (38)

1. Berendt, A. R., Simmons, D. L., Tansey, J., Newbold, C. I. & Marsh, K. (1989). Intercellular adhesion molecule 1 is an endothelial cell adhesion receptor for Plasmodium falciparum. Nature, 341, 57-59.
2. Berendt, A. R., McDowell, A., Craig, A. G., Snow, R., Msobo, M., Peshu, N. & Marsh, K. (1992). The binding site on ICAM1 for Plasmodium falciparum-infected erythrocytes overlaps, but is distinct from, the LFA-1 binding site. Cell, 68, 71-81.
3. Berendt, A. R., Ferguson, D. J. P., Gardner, J., Turner, G., Rowe, A., McCormick, C., Roberts, D., Craig, A., Pinches, R., Elford, B. C. & Newbold, C. I. (1994). Molecular mechanisms of sequestration in malaria. Parasitology, 108, S19-S28.
4. Blakemore, A. I., Tarlow, J. K., Cork, M. J., Gordon, C., Emery, P. & Duff, G. W. (1994). Interleukin 1 receptor gene polymorphism as a disease factor in systemic lupus erythematosus. Arthritis and Rheumatism, 37, 1380-1385.
5. Blakemore, A. I., Watson, P. F., Weetman, A. P. & Duff, G. W. (1995). Association of Graves' disease with an allele of the interleukin-1 receptor antagonist gene. Journal of Clinical Endocrinology and Metabolism, 80, 111-115.
6. Brewster, C. A., Kwiatkowski, D. & White, N. J. (1990). Neurological sequelae of cerebral malaria in children. Lancet, 336, 1039-1043.
7. Carlson, J., Helmby, H., Hill, A. V. S., Brewster, D., Greenwood, B. M. & Wahlgren, M. (1990). Human cerebral malaria: association with erythrocyte rosetting and lack of anti-rosetting antibodies. Lancet, 336, 1457-1460.
8. Clay, F. E., Cork, M. J., Tarlow, J. K., Blakemore, A. I. F., Harrington, C. I., Lewis, F. & Duff, G. W. (1994). Interleukin 1 receptor antagonist polymorphism association with lichen sclerosus. Human Genetics, 94, 407-410.
9. Cornillet, P., Philbert, K., Kazatchkine, M. D. & Cohen, J. H. M. (1991). Genomic determination of the CR1 (CD35) density polymorphism on erythrocytes using polymerase chain reaction amplification and HindIII restriction enzyme digestion. Journal of Immunological Methods, 136, 193-197.
10. Crusius, J. B. A., Pena, A. S., van Oosten, B. W., Bioque, G., Garcia, A., Dijkstra, C. D. & Polman, C. H. (1995). Interleukin-1 receptor antagonist gene polymorphism and multiple sclerosis. Lancet, 346, 979-980.
11. Danis, V. A., Millington, M., Hyland, V. J. & Grennan, D. (1995). Cytokine production by normal human monocytes: inter-subject variation and relationship to an IL-1 receptor antagonist (IL1-RA) gene polymorphism. Clinical and Experimental Immunology, 99, 303-310.
12. Dinarello, C. A. (1992). Role of interleukin-1 and tumour necrosis factor in systemic responses to infection and inflammation. In: Immunology: Basic Principles and Clinical Correlates, 2nd edition, Gallin, J. I., Goldstein, I. M. & Snyderman, R. (editors). New York: Raven Press, pp. 211-232.
13. Fearon, D. T. (1980). Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte. Journal of Experimental Medicine, 152, 20-30.
14. Fernandez-Reyes, D., Craig, A. G., Kyes, S. A., Peshu, N., Snow, R. W., Berendt, A. R., Marsh, K. & Newbold, C. I. (1997). A high frequency African coding polymorphism in the N-terminal domain of ICAM-1 predisposing to cerebral malaria in Kenya. Human Molecular Genetics, 6, 1357-1360.
15. Greenwood, B. M., Bradley, A. K., Greenwood, A. M., Byass, P., Jammeh, K., Marsh, K., Tulloch, S., Oldfield, F. S. J. & Hayes, R. (1987a). Mortality and morbidity from malaria among children in a rural area of The Gambia, West Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene, 81, 478-486.
16. Greenwood, B. M., Greenwood, A. M., Bradley, A. K., Tulloch, S., Hayes, R. & Oldfield, F. S. (1987b). Deaths in infancy and early childhood in a well-nourished, rural, West African population. Annals of Tropical Paediatrics, 7, 91-99.
17. Greenwood, B., Marsh, K. & Snow, R. (1991). Why do some African children develop severe malaria? Parasitology Today, 7, 277-281.
18. Hill, A. V. S. (1992). Malaria resistance genes: a natural selection. Transactions of the Royal Society of Tropical Medicine and Hygiene, 86, 225-226.
19. Hill, A. V. S. (1996). Genetics of infectious disease resistance. Current Opinions in Genetics and Development, 6, 271-274.
20. Hill, A. V. S., Allsopp, C. E. M., Kwiatkowski, D., Anstey, N. M.,Twumasi, P., Rowe, P. A., Bennett, S., Brewster, D., McMichael, A. J. & Greenwood, B. M. (1991). Common West African HLA antigens are associated with protection from severe malaria. Nature, 352, 595-560.
21. Kwiatkowski, D., Hill, A. V. S., Sambon, I., Twumasi, P., Castracan, J., Manogue, K. R., Cerami, A., Brewster, D. R. & Greenwood, B. M. (1990). TNF concentration in fatal cerebral, non-fatal cerebral and uncomplicated Plasmodium falciparum malaria. Lancet, 336, 1201-1204.
22. Mansfield, J. C., Holden, H., Tarlow, J. K., Di Giovine, F. S., McDowell, T. L., Wilson, A. G., Holdsworth, C. D. & Duff, G. W. (1994). Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist. Gastroenterology, 106, 637-642.
23. Marsh, K. (1992). Malaria - a neglected disease? Parasitology Today, 104, S53-S69.
24. McGuire,W., Hill, A. V. S., Allsopp, C. E. M., Greenwood, B. M. & Kwiatkowski, D. (1994). Variation in theTNF-α promoter region associated with susceptibility to cerebral malaria. Nature, 371, 508-511.
25. Murray, C. J. L. & Lopez, A. D. (1997). Mortality by cause for eight regions of the world: Global Burden of Disease Study. Lancet, 349, 1269-1276.
26. Newbold, C., Warn, P., Black, G., Berendt, A., Craig, A., Snow, B., Msobo, M., Peshu, N. & Marsh, K. (1997). Receptor-specific adhesion and clinical disease in Plasmodium falciparum. American Journal of Tropical Medicine and Hygiene, 57, 389-398.
27. Ockenhouse, C. F., Betageri, R., Springer, T. A. & Staunton, D. E. (1992). Plasmodium falciparum-infected erythrocytes bind ICAM1 at a site distinct from LFA-1, MAC-1 and human rhinovirus. Cell, 68, 63-69.
28. Ringwald, P., Peyron, F., Lepers, J. P., Rabarison, P., Rakotomalala, C., Razanamparany, M., Rabodonirina, M., Roux, J. & Le Bras, J. (1993). Parasite virulence factors during falciparum malaria rosetting, cytoadherence by cytokines. Infection and Immunity, 61, 5198-5204.
29. Rowe, J. A., Moulds, J. M., Newbold, C. I. & Miller, L. H. (1997). P. falciparum rosetting mediated by a parasite-variant erythrocyte membrane protein and complement-receptor 1. Nature, 388, 292-295.
30. Ruwende, C., Khoo, S. C., Snow, R., Yates, N. R., Kwiatkowski, D., Gupta, S., Warn, P., Allsopp, C. E. M., Gilbert, S. C., Peschu, N., Newbold, C. I., Greenwood, B. M., Marsh, K. & Hill, A. V. S. (1995). Natural selection of hemi- and heterozygotes for G6PD deficiency in Africa by resistance to severe malaria. Nature, 376, 246-249.
31. Tarlow, J. K., Blakemore, I. F., Lennard, A., Solari, R., Hughes, H. N., Steinkasserer, A. & Duff, G. W. (1993). Polymorphism in the human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat. Human Genetics, 91, 403-404.
32. Thursz, M., Kwiatkowski, D., Allsopp, C. E. M., Greenwood, B. M., Thomas, H. C. & Hill, A. V. S. (1995). Association between an MHC class II allele and clearance of hepatitis B virus in The Gambia. New England Journal of Medicine, 332, 1065-1069.
33. Treutiger, C. J., Hedlund, I., Helmby, H., Carlson, J., Jepson, A., Twumasi, P., Kwiatkowski, D., Greenwood, B. M. & Wahlgren, M. (1992). Rosette formation in Plasmodium falciparum isolates and anti-rosette activity of sera from Gambians with cerebral or uncomplicated malaria. American Journal of Tropical Medicine and Hygiene, 46, 503-510.
34. Turner, G. D., Morrison, H., Jones, M., Davis, T. M. E., Looareesuwan, S., Buley, I. D., Gatter, K. C., Newbold, C. I., Pukritayakamee, S., Nagachinta, B., White, N. J. & Berendt, A. R. (1997). An immunohistochemical study of the pathology of fatal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration. American Journal of Pathology, 145, 1057-1069.
35. Voraberger, G., Schafer, R. & Stratowa, C. (1991). Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region. Journal of Immunology, 147, 2777-2786.
36. Wilson, J. G., Tedder, T. F. & Fearon, D. T. (1983). Characterization of human T lymphocytes that express the C3b receptor. Journal of Immunology, 131, 684-689.
37. Wilson, J. G., Murphy, E. F., Wong, W. W., Klickstein, L. B., Weis, J. H. & Fearon, D. T. (1986). Identification of a restriction fragment length polymorphism by a CR1 cDNA that correlates with the number of CR1 on erythrocytes. Journal of Experimental Medicine, 164, 50-59.
38. Wong, W. W., Cahill, J. A., Rosen, M. D., Kennedy, C. A., Bonaccio, E. T., Morris, M. J., Wilson, J. G., Klickstein, L. B. & Fearon, D. T. (1989). Structure of the human CR1 gene. Molecular basis of the structural and quantitative polymorphisms and identification of a new CR1-like allele. Journal of Experimental Medicine, 169, 847-863.